MicroRNAs and Mitochondrial Dynamics in Heart Regeneration
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: closed (25 January 2024) | Viewed by 215
Special Issue Editors
Interests: molecular cardiology; cardiovascular research; cardiac regeneration; cardiomyocyte survival; cardiomyocyte death
Special Issues, Collections and Topics in MDPI journals
Interests: cardiomyopathies; hematopoietic mesenchymal cells; adipose-derived mesenchymal stems; exosomes; miRNAs; cardiac regeneration; cardiac protection and cardiac remodeling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent decades, research has shown key roles for MicroRNAs (miRNAs) in the post-transcriptional regulation of gene expression in major cardiac physiological and pathological events. Indeed, there has been an exponential growth in studies reporting the contribution of microRNAs to various processes underlying the pathology of cardiac muscle and as well as to potential therapeutic targets.
On the other hand, cardiomyocyte mitochondria are known to be highly dynamic, continuously moving and undergoing fission and fusion, forming interconnected networks; however, the involvement of these processes in heart disease and health is not fully understood. Abnormal mitochondrial dynamics lead to dysfunctional mitochondria and thus disrupt energy production and increase oxidative stress, resulting in cardiomyocyte apoptosis and heart tissue damage.
In this Special Issue entitled “MicroRNAs and Mitochondrial Dynamics in Heart Regeneration”, we would like to present the current progress in the heart field regarding these two important topics. We welcome original research papers and updated reviews on new insights into the pathogenesis, regulatory pathways and beneficial roles of miRNAs and mitochondrial dynamics in heart regeneration.
Dr. Eltyeb Abdelwahid
Dr. Katherine Athayde Teixeira de Carvalho
Guest Editors
Manuscript Submission Information
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Keywords
- microRNAs
- cardiomyocyte mitochondria
- regulatory pathways
- mitochondrial dynamics
- heart regeneration
