Genetics of Embryo Development and Reproduction Research

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: 20 August 2024 | Viewed by 80

Special Issue Editor

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Guest Editor
1. Laboratory Animal Center, Xi’an Jiaotong University, Xi’an, China
2. Translational Medicine Institute, Institute of Cardiovascular Science, Xi’an Jiaotong University, Xi’an, China
Interests: animal model; embryogenesis; transgenic; genetics; lipid metabolism
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Special Issue Information

Dear Colleagues,

The fertilization of oocyte and sperm to produce a new organism is the culmination of numerous intricately regulated cellular processes. After fertilization, gametes develop from a highly differentiated state to a pluripotent state, and then they undergo early embryogenesis, which is considered to be one of the most crucial lifespan phases. During this process, paternal and maternal chromatin structures and genomes undergo dramatic changes, with the latter experiencing genome-wide epigenetic modifications or reprogramming. The transcriptome, proteome, and metabolome of the early embryo also exhibit significant transformations, all of which can regulate the events of embryonic development and even the entire lifespan of offspring.

Until now, several important theories and mechanisms concerning the regulation of early animal embryogenesis have been elucidated, triggering the emergence of important technologies such as assisted reproduction, animal breeding, the creation of gene-editing animals, and so on. However, the early embryonic development process is complex, and its mechanisms are not fully understood.

This Special Issue will focus on valuable findings associated with the genetic programs of early animal embryogenesis by utilizing new research in this area.  

Prof. Dr. Enqi Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • animal
  • embryogenesis
  • fertilization
  • zygotic genome activation
  • reprogramming
  • chromatin structure
  • epigenetics

Published Papers

This special issue is now open for submission.
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