Physiological Changes in Fish Exposed to Emerging Stressors

A special issue of Fishes (ISSN 2410-3888). This special issue belongs to the section "Environment and Climate Change".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 1629

Special Issue Editors


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Guest Editor
Laboratório de Patologia Experimental, UFMS, Campo Grande, Brazil
Interests: ecotoxicology; toxicology; fish; amphibians; pathology; histopathology; morphology

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Guest Editor
Instituto de Biociências, Federal University of Mato Grosso do Sul, Campo Grande, Brazil
Interests: ecotoxicology; toxicology; fish; amphibians; pathology; histopathology; morphology

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Guest Editor
INQUISAL-CONICET, Universidad Nacional de San Luis, San Luis, Argentina
Interests: ecotoxicology; toxicology; fish; amphibians; pathology; histopathology; morphology

Special Issue Information

Dear Colleagues,

Regardless of the various concepts and terminologies applied, stress and stressors have long been investigated in marine and freshwater ichthyology as part of our evolution. This multidisciplinary field involves researchers examining the effects of stress on aquatic organisms. However, in recent years, a range of compounds, such as phthalates, the bisphenol family, pharmaceuticals, nanomaterials, a new generation of pesticides, industrial pollutants, personal care products, etc., now known as "emerging" compounds, have taken precedent in the literature since their direct or indirect effects on the aquatic ecosystem and human health remain unknown. Furthermore, the toxicity of chemical, physical and biological agents increases in direct proportion to the development of science and technology, making an increasing number of natural or synthetic products available to the population in the form of food, pharmaceuticals, agrochemicals, and personal care compounds. On the other hand, fish constitute a class of organisms with the greatest taxonomic and habitat diversity on the planet. Moreover, they represent the impact of human activities on aquatic ecosystems and productive systems. Therefore, the complexity of this topic makes it a real challenge to update scientific knowledge on the range of emerging biotic and abiotic factors to which the environment and organisms are subjected. In this context, this Special Issue of Fishes offers its readers a broad approach to "Physiological Changes in Fish Exposed to Emerging Stressors" to support new debates and advance knowledge on this broad topic. We hope that you enjoy this great read!

Prof. Dr. Carlos Eurico S. Fernandes
Dr. Lilian Franco-Belussi
Dr. Juan Manuel Pérez-Iglesias
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fishes
  • ecotoxicology
  • pollutants
  • metabolism
  • biological cycles
  • physiopathology
  • environmental chemistry
  • endocrine disruptors
  • oxidative stress

Published Papers (1 paper)

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Research

15 pages, 3674 KiB  
Communication
Histopathological and Immunohistochemical Features and Expression Patterns of Cytochrome p450 1 Family Genes in Black Rockfish (Sebastes schlegelii): Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin and β-Naphthoflavone
by Soo-Ji Woo, Min-Soo Joo, So-Sun Kim, Hae-Kyun Yoo and Jung-Jun Park
Fishes 2023, 8(12), 583; https://doi.org/10.3390/fishes8120583 - 29 Nov 2023
Viewed by 1251
Abstract
The climate crisis and growing petroleum demand have put the health of aquatic animals in jeopardy. Fish are sensitive to chemical pollutants in aquatic environments, such as polycyclic aromatic hydrocarbons, dioxins, and dibenzofurans. This study investigated the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and β-naphthoflavone [...] Read more.
The climate crisis and growing petroleum demand have put the health of aquatic animals in jeopardy. Fish are sensitive to chemical pollutants in aquatic environments, such as polycyclic aromatic hydrocarbons, dioxins, and dibenzofurans. This study investigated the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and β-naphthoflavone (β-NF) exposure on histopathological and immunohistochemical features and expression patterns of cytochrome P450 1 (CYP1) family genes in black rockfish, Sebastes schlegelii. Histopathological alterations in the liver included congested central vein, sinusoidal dilatation, lymphocyte infiltration, and severe vacuolation within hepatocytes. The most prevalent alterations in TCDD-exposed kidneys were glomerular enlargement, narrowing of tubular lumen, melanomacrophage centers (MMCs), and necrosis. Moreover, CYP1A immunostaining was strong in renal tubules following TCDD exposure. All CYP1 family genes (CYP1A, CYP1B, CYP1C1, and CYP1C2) were significantly increased in the gills, liver, and kidney exposed to TCDD. Similarly, a significant increase of CYP1A mRNA expression in the kidney was observed upon exposure to TCDD (30.9-folds) and β-NF (25.5-folds) compared with that of the control group (p < 0.05). TCDD and β-NF exposure exerted more adverse effects on the kidney than the liver, and TCDD had a greater in vivo toxic effect than β-NF. The combined histopathological, immunohistochemical, and molecular alternations may be helpful for diagnosing chemical contaminant exposure in S. schlegelii. Full article
(This article belongs to the Special Issue Physiological Changes in Fish Exposed to Emerging Stressors)
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