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Diagnostics
Special Issues
Evaluation, Diagnosis and Prognosis in Orthopedic Disease
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Evaluation, Diagnosis and Prognosis in Orthopedic Disease

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 5770

Special Issue Editor

Dr. Chenkun Liaw

E-Mail Website
Guest Editor
1. Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
2. Graduate Institute of Biomedical Optomechatronics, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan
Interests: orthopaedics; computer science; robot surgery; hospital computer system; pooling PCR strategy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Orthopedics has seen great development in recent decades. The field has seen the development of new implants, such as the locking plate and trans-pedicle screw, and new prosthesis methods, including uni-compartment total knee prosthesis and reverse total shoulder prosthesis. Additionally, new, minimally invasive operational procedures, stem cells treatments including new treatments for cartilage regeneration and platelet-rich plasma treatment and computer operation methods like navigation, robot surgery, patient specific instrument (PSI), 3D printing implants and 3D printing prosthesis have been employed.

Questions remain as to the beneficial nature of these new methods to patients? Each new method requires academic evaluation before the procedure and close monitoring of the patient's prognosis after treatment has concluded. This issue focuses on a variety of novel and interesting methods of diagnosis and monitoring before and after treatment of orthopaedic diseases, including orthopedic imaging and pathology testing, such as:  X-ray imaging, arthrogram, magnetic resonance imaging (MRI), computed tomography (CT), electromyogram (EMG), ultrasound, arthroscopy, myelogram, radionuclide bone scans, blood tests and pathological analysis.

We intend to establish a collection of excellent publications around this theme and provide a venue for networking and communication between scholars in the field of subjects related to the evaluation, diagnosis and prognosis of orthopedic disease. We noticed that some current evaluations may not be sufficiently scientific or even contain mistakes. Thus, thorough analyses of these evaluation tools are also welcome. We look forward to receiving these manuscripts, hope to clarify related misunderstandings, and be the benchmark for other research in this field going forward. Original research articles, reviews, short communications, and interesting images are welcome, as well as either clinical or basic research.

Dr. Chenkun Liaw
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical evaluation
  • radiological evaluation
  • prognosis
  • diagnosis

Published Papers (3 papers)

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Research

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12 pages, 3173 KiB  
Article
Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
by Tea Duvančić, Andreja Vukasović Barišić, Ana Čizmić, Mihovil Plečko, Ivan Bohaček and Domagoj Delimar
Diagnostics 2024, 14(7), 779; https://doi.org/10.3390/diagnostics14070779 - 8 Apr 2024
Viewed by 727
Abstract
Developmental dysplasia of the hip (DDH) presents varying degrees of femoral head dislocation, with severe cases leading to the formation of a new articular surface on the external side of the iliac bone—the neoacetabulum. Despite conventional understanding suggesting otherwise, a tissue resembling hyaline [...] Read more.
Developmental dysplasia of the hip (DDH) presents varying degrees of femoral head dislocation, with severe cases leading to the formation of a new articular surface on the external side of the iliac bone—the neoacetabulum. Despite conventional understanding suggesting otherwise, a tissue resembling hyaline cartilage is found in the neoacetabulum and acetabulum of Crowe III and IV patients, indicating a potential for hyaline cartilage development without mechanical pressure. To test this theory, acetabular and femoral head cartilage obtained from patients with DDH was stained with hematoxylin–eosin and toluidine blue. The immunohistochemical analysis for collagen types II and VI and aggrecan was performed, as well as delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) analysis on a 7.0 T micro-MRI machine. The results obtained from DDH patients were compared to those of the control groups. Hyaline cartilage was found in the neoacetabulum and the acetabulum of patients with DDH. The nature of the tissue was confirmed with both the histological and the MRI analyses. The results of this study proved the presence of hyaline cartilage in patients with DDH at anatomical regions genetically predisposed to be bone tissue and at regions that are not subjected to mechanical stress. This is the first time that the neoacetabular cartilage of patients with advanced stages of DDH has been characterized in detail. Full article
(This article belongs to the Special Issue Evaluation, Diagnosis and Prognosis in Orthopedic Disease)
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5 pages, 1092 KiB  
Interesting Images
A Patient with Acute Necrotizing Fasciitis after a Total Knee Replacement: A Case Report
by Shu-Hao Chang, Ching-Chuan Jiang, Tom J. Liu, Yu-Feng Kuo and Ping-Chun Yeh
Diagnostics 2023, 13(6), 1125; https://doi.org/10.3390/diagnostics13061125 - 16 Mar 2023
Viewed by 2047
Abstract
Necrotizing fasciitis is a relatively rare and serious fatal soft-tissue infection that is characterized by a rapidly spreading bacterial infection located in the subcutaneous tissues. We report a 59-year-old man who was diagnosed with acute necrotizing fasciitis, following a primary total knee replacement. [...] Read more.
Necrotizing fasciitis is a relatively rare and serious fatal soft-tissue infection that is characterized by a rapidly spreading bacterial infection located in the subcutaneous tissues. We report a 59-year-old man who was diagnosed with acute necrotizing fasciitis, following a primary total knee replacement. He received primary total knee replacement that was uneventful and smooth intraoperatively. An immediate high fever was reported in the next few days, with several complications, confirming a diagnosis of necrotizing fasciitis. The most effective treatment for this disease is a rapid primary diagnosis and surgical debridement. Gold standard treatment includes intravenous therapy, such as antibiotics, surgical debridement, and intensive care. As a result of possible GI complications that triggered necrotizing fasciitis, the patient underwent flap reconstruction. This report’s aim is to review the comprehensive treatment, management, and experience of necrotizing fasciitis, highlighting the roles with a multidisciplinary care team for improving the condition of this patient. Full article
(This article belongs to the Special Issue Evaluation, Diagnosis and Prognosis in Orthopedic Disease)
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14 pages, 28548 KiB  
Systematic Review
Indications for and Outcomes of Three Unilateral Biportal Endoscopic Approaches for the Decompression of Degenerative Lumbar Spinal Stenosis: A Systematic Review
by Anh Tuan Bui, Giam Minh Trinh, Meng-Huang Wu, Tung Thanh Hoang, Ming-Hsiao Hu and Jwo-Luen Pao
Diagnostics 2023, 13(6), 1092; https://doi.org/10.3390/diagnostics13061092 - 14 Mar 2023
Cited by 4 | Viewed by 2149
Abstract
Objective: In this systematic review, we summarized the indications for and outcomes of three main unilateral biportal endoscopic (UBE) approaches for the decompression of degenerative lumbar spinal stenosis (DLSS). Methods: A comprehensive search of the literature was performed using Ovid Embase, PubMed, Web [...] Read more.
Objective: In this systematic review, we summarized the indications for and outcomes of three main unilateral biportal endoscopic (UBE) approaches for the decompression of degenerative lumbar spinal stenosis (DLSS). Methods: A comprehensive search of the literature was performed using Ovid Embase, PubMed, Web of Science, and Ovid’s Cochrane Library. The following information was collected: surgical data; patients’ scores on the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and Macnab criteria; and surgical complications. Results: In total, 23 articles comprising 7 retrospective comparative studies, 2 prospective comparative studies, 12 retrospectives case series, and 2 randomized controlled trials were selected for quantitative analysis. The interlaminar approach for central and bilateral lateral recess stenoses, contralateral approach for isolated lateral recess stenosis, and paraspinal approach for foraminal stenosis were used in 16, 2, and 4 studies, respectively. In one study, both interlaminar and contralateral approaches were used. L4-5 was the most common level decompressed using the interlaminar and contralateral approaches, whereas L5-S1 was the most common level decompressed using the paraspinal approach. All three approaches provided favorable clinical outcomes at the final follow-up, with considerable improvements in patients’ VAS scores for leg pain (63.6–73.5%) and ODI scores (67.2–71%). The overall complication rate was <6%. Conclusions: The three approaches of UBE surgery are effective and safe for the decompression of various types of DLSS. In the future, long-term prospective studies and randomized control trials are warranted to explore this new technique further and to compare it with conventional surgical techniques. Full article
(This article belongs to the Special Issue Evaluation, Diagnosis and Prognosis in Orthopedic Disease)
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