Special Issue "Imaging of Cartilage and Intervertebral Disks"

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 3140

Special Issue Editors

Institute for Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Düsseldorf, Germany
Interests: MRI; musculoskeletal diseases; hybrid imaging
Special Issues, Collections and Topics in MDPI journals
Dr. Ingrid Moller
Guest Editor
Instituto Poal, University of Barcelona, Barcelona, Spain
Interests: musculo skeletal ultrasound

Special Issue Information

Dear Colleagues,

This Special Issue, "Imaging of Cartilage and Intervertebral Disks", aims to attract high-quality research focusing on diverse and advanced imaging techniques. All submissions dealing with different magnetic resonance imaging (MRI) techniques are welcome. Among these, both advanced morphological and ultrastructural and compositional MRIs are of high relevance. Of special interest are studies on UTE, T1rho, gagCEST, and sodium MRI in degenerative, inflammatory, and traumatic diseases of joints and the spine. Additionally, manuscripts on advanced computed tomography (CT) techniques, such as micro-CT and dual-energy CT, are appreciated. However, studies focusing on image acquisition and image analysis and different pre- and post-processing algorithms are of significance. In this regard, deep- and machine-learning-based approaches will be considered for publication. Disease entities of relevance include but are not limited to osteoarthritis, degenerative disk disease, rheumatoid and psoriatic arthritis, and traumatic osteochondral lesions of joints.

Overall, basic and experimental research with proof of concept studies are of equal relevance as clinical trials and confirmation studies. We are eagerly looking for excellent research studies and are very much looking forward to your valuable contributions.

Dr. Daniel B. Abrar
Dr. Ingrid Moller
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • MRI
  • CT
  • T1rho
  • UTE
  • gagCEST
  • DECT
  • osteoarthritis
  • inflammatory joint disease

Published Papers (1 paper)

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14 pages, 1179 KiB  
Changes in T2 Relaxation Time Mapping of Intervertebral Discs Adjacent to Vertebrae after Kyphoplasty Correlate with the Physical Clinical Outcome of Patients
Diagnostics 2022, 12(3), 605; https://doi.org/10.3390/diagnostics12030605 - 27 Feb 2022
Cited by 1 | Viewed by 2683
(1) Background: To assess whether clinical outcomes correlate with tissue changes in the intervertebral discs (IVDs) after kyphoplasty as treatment for vertebral fractures, quantitative MRI was applied. (2) Methods: Quantitative T2 mapping acquired in a 3 T MRI scanner of the thoracolumbar spine [...] Read more.
(1) Background: To assess whether clinical outcomes correlate with tissue changes in the intervertebral discs (IVDs) after kyphoplasty as treatment for vertebral fractures, quantitative MRI was applied. (2) Methods: Quantitative T2 mapping acquired in a 3 T MRI scanner of the thoracolumbar spine was performed in 20 patients two years after kyphoplasty. The IVDs adjacent and nonadjacent to the treated vertebrae were divided into six regions of interest (ROI), which were further categorised into inner (ROI 2–5) and outer (ROI 1 and 6) parts of the IVDs, and the T2 values were analysed. T2 values of adjacent discs were correlated with the items of questionnaires evaluating the clinical outcome (i.e., 36-Item Short Form Survey). (3) Results: Lower T2 values in adjacent IVDs correlated with poorer physical outcome two years after kyphoplasty. The inner part of the IVDs adjacent to treated vertebrae showed statistically significant lower T2 values in segments L2/L3 and L3/L4 compared to nonadjacent ones. Patients with lower T2 values showed more pain and physical limitations in everyday life. (4) Conclusions: Quantitative T2 mapping can detect IVD degeneration in patients after kyphoplasty and correlates with the physical outcome. This technique could help to gain better insights into alterations in tissue composition following kyphoplasty and the consequences for the patients’ quality of life. Full article
(This article belongs to the Special Issue Imaging of Cartilage and Intervertebral Disks)
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