Image-Based Diagnostics and Radiometabolic Therapy of Differentiated Thyroid Cancer: 3rd Edition
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 1092
Special Issue Editors
Interests: nuclear medicine; image-based diagnostics; SPECT; SPECT/CT; PET/CT; molecular breast imaging; oncology (breast cancer, lung cancer, thyroid cancer, neuroendocrine tumors, prostate cancer); radiomics; neurodegenerative disorders; radiometabolic therapy
Special Issues, Collections and Topics in MDPI journals
Interests: nuclear medicine; imaging; integrated imaging; high resolution scintigraphic detectors; heart failure; radionuclide therapy; dosimetry; target alpha therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Well-differentiated thyroid cancer (DTC), which includes papillary carcinoma and follicular carcinoma, represents the vast majority of all thyroid cancers and the most frequent endocrine malignancy. The incidence of DTC is increasing worldwide due to the widespread use of thyroid ultrasound (US), but mortality is stable over the years as more cancers are diagnosed at a very early stage.
FNAC, in association with neck US, represents the method of choice for the pre-surgical diagnosis and loco-regional staging of DTC.
After surgery, neck US and 131I-Whole-Body scan, the latter preferably integrated with SPECT/CT, in combination with the serum assay of basal/stimulated Thyroglobulin (TG) and Ab-TG, are currently the diagnostic tools of preference.
18FDG-PET adds important prognostic information and is especially indicated in the presence of elevated serum levels of TG and a negative radioiodine scan.
Further diagnostic tools, such as computed tomography and MRI, may be considered in selected cases. Moreover, novel diagnostic techniques (e.g., 18FDG-PET/MRI) and radiotracers (e.g., Tetrafluoroborate) are ongoing in this field.
DTC is usually characterized by a favorable prognosis and maintains the ability to concentrate iodine, thus making radiometabolic treatment with 131Iodine (RAI) the most effective therapy after surgery. However, recurrent DTC may become poorly differentiated over time and lose the ability to concentrate iodine. Alternative therapies (e.g., molecular targeted therapy) should be considered in RAI refractory disease.
In this Special Issue, we encourage researchers to submit original papers, review articles, brief communications, or comments on current image-based diagnostics and radiometabolic therapy of DTC. Papers focused on novel diagnostic and therapeutic tools, radiomics, and personalized medicine are also welcome.
Prof. Dr. Angela Spanu
Dr. Giuseppe De Vincentis
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- differentiated thyroid cancer
- neck ultrasound
- diagnostic radioiodine scan
- 131I-SPECT/CT
- FDG-PET/CT
- computed tomography
- MRI
- PET/MRI
- tetrafluoroborate
- 131I-iodine therapy
- dosimetry
- theranostics
- thyroglobulin
- radiomics
- personalized medicine
