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Diagnostics
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Clinical Applications of Cardiac Magnetic Resonance in Adults and Children...
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Clinical Applications of Cardiac Magnetic Resonance in Adults and Children 2.0

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 5372

Special Issue Editors

Prof. Dr. Lukasz Malek

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Guest Editor
Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, National Institute of Cardiology, Niemodlińska str 33, 04-635 Warsaw, Poland
Interests: sports cardiology; cardiac magnetic resonance
Special Issues, Collections and Topics in MDPI journals
Dr. Łukasz Mazurkiewicz

E-Mail Website
Guest Editor
Departament of Cardiomyopathies, Cardiac Magnetic Resonance Unit, National Institute of Cardiology, Alpejska str 42, 04-682 Warsaw, Poland
Interests: heart failure; echocardiography; cardiac function; cardiomyopathies; chronic heart failure; cardiac imaging; acute heart failure; cardiac catheterization; cardiovascular imaging; heart transplantation
Special Issues, Collections and Topics in MDPI journals
Dr. Joanna Petryka-Mazurkiewicz

E-Mail Website
Guest Editor
Department of Coronary and Structural Heart Diseases, CMR Unit, National Institute of Cardiology, Alpejska 42, 04-682 Warsaw, Poland
Interests: ischemic heart disease; cardiomyopathies; heart failure; resynchronization therapy; cardiac imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Over the last two decades, cardiac magnetic resonance (CMR) has evolved from a promising noninvasive imaging method into a diagnostic cornerstone in cardiology for both adults and children. Increased scanner availability, decreased scanning times, and technical advancements, including parametric imaging, allowing detailed myocardial tissue characterisation, have opened the doors for the widespread clinical use of CMR. These recent advances necessitate a summarisation of recent findings to assess the clinical value of this method in various clinical cardiology scenarios, including its input in clinical decision making, prognosis and outcomes, and cost effectiveness. Therefore, we are seeking research submissions focused on the abovementioned areas, including systematic reviews and meta-analyses, original research, and short communications providing important clinical data, as well as comprehensive case reports. Translational or cross-disciplinary studies and emerging clinical applications in CMR are also welcome.

Prof. Dr. Lukasz Malek
Dr. Łukasz Mazurkiewicz
Dr. Joanna Petryka-Mazurkiewicz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • functional imaging
  • parametric imaging
  • late gadolinium enhancement
  • new imaging techniques
  • differential diagnosis
  • prognosis
  • outcomes
  • cost-effectiveness

Published Papers (3 papers)

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Research

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12 pages, 6687 KiB  
Article
Right Ventricular Strain by Magnetic Resonance Feature Tracking Is Largely Afterload-Dependent and Does Not Reflect Contractility: Validation by Combined Volumetry and Invasive Pressure Tracings
by Andreas Rolf, Till Keller, Jan Sebastian Wolter, Steffen Kriechbaum, Maren Weferling, Stefan Guth, Christoph Wiedenroth, Eckhard Mayer, Christian W. Hamm, Ulrich Fischer-Rasokat and Julia Treiber
Diagnostics 2022, 12(12), 3183; https://doi.org/10.3390/diagnostics12123183 - 16 Dec 2022
Cited by 2 | Viewed by 1457
Abstract
Cardiac magnetic resonance (CMR) is currently the gold standard for evaluating right ventricular (RV) function, which is critical in patients with pulmonary hypertension. CMR feature-tracking (FT) strain analysis has emerged as a technique to detect subtle changes. However, the dependence of RV strain [...] Read more.
Cardiac magnetic resonance (CMR) is currently the gold standard for evaluating right ventricular (RV) function, which is critical in patients with pulmonary hypertension. CMR feature-tracking (FT) strain analysis has emerged as a technique to detect subtle changes. However, the dependence of RV strain on load is still a matter of debate. The aim of this study was to measure the afterload dependence of RV strain and to correlate it with surrogate markers of contractility in a cohort of patients with chronic thromboembolic pulmonary hypertension (CTEPH) under two different loading conditions before and after pulmonary endarterectomy (PEA). Between 2009 and 2022, 496 patients with 601 CMR examinations were retrospectively identified from our CTEPH cohort, and the results of 194 examinations with right heart catheterization within 24 h were available. The CMR FT strain (longitudinal (GLS) and circumferential (GCS)) was computed on steady-state free precession (SSFP) cine CMR sequences. The effective pulmonary arterial elastance (Ea) and RV chamber elastance (Ees) were approximated by dividing mean pulmonary arterial pressure by the indexed stroke volume or end-systolic volume, respectively. GLS and GCS correlated significantly with Ea and Ees/Ea in the overall cohort and individually before and after PEA. There was no general correlation with Ees; however, under high afterload, before PEA, Ees correlated significantly. The results show that RV GLS and GCS are highly afterload-dependent and reflect ventriculoarterial coupling. Ees was significantly correlated with strain only under high loading conditions, which probably reflects contractile adaptation to pulsatile load rather than contractility in general. Full article
(This article belongs to the Special Issue Clinical Applications of Cardiac Magnetic Resonance in Adults and Children 2.0)
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10 pages, 1709 KiB  
Article
T1 Mapping MOLLI 5(3)3 Acquisition Scheme Yields High Accuracy in 1.5 T Cardiac Magnetic Resonance
by Patrick Krumm, Petros Martirosian, Alexander Brendel, Jens M. Kübler, Jan M. Brendel, Sebastian Gassenmaier, Arne Estler, Meinrad Gawaz, Konstantin Nikolaou and Simon Greulich
Diagnostics 2022, 12(11), 2729; https://doi.org/10.3390/diagnostics12112729 - 8 Nov 2022
Cited by 1 | Viewed by 1423
Abstract
Objectives: To systematically compare two modified Look-Locker inversion recovery (MOLLI) T1 mapping sequences and their impact on (1) myocardial T1 values native, (2) post-contrast and (3) extracellular volume (ECV). Methods: 200 patients were prospectively included for 1.5 T CMR for work-up of ischemic [...] Read more.
Objectives: To systematically compare two modified Look-Locker inversion recovery (MOLLI) T1 mapping sequences and their impact on (1) myocardial T1 values native, (2) post-contrast and (3) extracellular volume (ECV). Methods: 200 patients were prospectively included for 1.5 T CMR for work-up of ischemic or non-ischemic cardiomyopathies. To determine native and post-contrast T1 for ECV calculation, two different T1 mapping MOLLI acquisition schemes, 5(3)3 (designed for native scans with long T1) and 4(1)3(1)2 (designed for post-contrast scans with short T1), were acquired in identical mid-ventricular short-axis slices. Both schemes were acquired in native and post-contrast scans. Results: Datasets from 163 patients were evaluated (age 55 ± 17 years; 38% female). Myocardial T1 native for 5(3)3 was 1017 ± 42 ms vs. 956 ± 40 ms for 4(1)3(1)2, with mean intraindividual difference −61 ms (p < 0.0001). Post-contrast myocardial T1 in patients was similar for both acquisition schemes, with 494 ± 48 ms for 5(3)3 and 490 ± 45 ms for 4(1)3(1)2 and mean intraindividual difference −4 ms. Myocardial ECV for 5(3)3 was 27.6 ± 4% vs. 27 ± 4% for 4(1)3(1)2, with mean difference −0.6 percentage points (p < 0.0001). Conclusions: The T1 MOLLI 5(3)3 acquisition scheme provides a reliable estimation of myocardial T1 for the clinically relevant range of long and short T1 values native and post-contrast. In contrast, the T1 MOLLI 4(1)3(1)2 acquisition scheme may only be used for post-contrast scans according to its designed purpose. Full article
(This article belongs to the Special Issue Clinical Applications of Cardiac Magnetic Resonance in Adults and Children 2.0)
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Review

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12 pages, 1272 KiB  
Review
Myocardial Infarction in Young Athletes
by Mariusz Dotka and Łukasz A. Małek
Diagnostics 2023, 13(15), 2473; https://doi.org/10.3390/diagnostics13152473 - 25 Jul 2023
Viewed by 1867
Abstract
Myocardial infarction (MI) in young athletes is very rare but can have serious consequences, including sudden cardiac death (SCD), an increased proarrhythmic burden in future life, and/or heart failure. We present two cases of young athletes with MI. They did not have previous [...] Read more.
Myocardial infarction (MI) in young athletes is very rare but can have serious consequences, including sudden cardiac death (SCD), an increased proarrhythmic burden in future life, and/or heart failure. We present two cases of young athletes with MI. They did not have previous symptoms, traditional risk factors, or a family history of MI. One case involves a 37-year-old male amateur athlete who experienced two MI following intense physical exertion, likely due to the erosion of an insignificant atherosclerotic plaque caused by a sudden increase in blood pressure during exercise. The second case describes a 36-year-old male semi-professional runner who collapsed at the finish line of a half-marathon and was diagnosed with hypertrophic cardiomyopathy. The heart’s oxygen demand–supply mismatch during intensive exercise led to MI. Following the case presentation, we discuss the most common causes of MI in young athletes and their mechanisms, including spontaneous coronary artery dissection, chest trauma, abnormalities of the coronary arteries, coronary artery spasm, plaque erosion, hypercoagulability, left ventricular hypertrophy, and anabolic steroids use. Full article
(This article belongs to the Special Issue Clinical Applications of Cardiac Magnetic Resonance in Adults and Children 2.0)
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