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Diagnostics
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Advances in Point-of-Care Ultrasonography
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Advances in Point-of-Care Ultrasonography

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Point-of-Care Diagnostics and Devices".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 6276

Special Issue Editor

Dr. Ibadete Bytyçi

E-Mail Website
Guest Editor
1. University Clinical Centre of Kosovo, Prishtina, 1000 Prishtina, Kosovo
2. Department of Public Health and Clinical Medicine, Umeå University, 90187 Umeå, Sweden
Interests: left atrium function; anticoagulation in paroxysmal atrial fibrillation; coronary imaging; coronary artery disease

Special Issue Information

Dear Colleagues,

Cardiovascular disease has been showing patterns of extensive rise in prevalence globally, affecting quality of life and leading as a cause of death worldwide.

It has been really a challenge for modern medicine to diagnose cardiovascular disease in early stages because of a large array of etiological factors and the insidious nature that leads to functional disability.

Echocardiography is witnessed as the gold standard for evaluation of patients with heart failure. Furthermore, recent technological advances have provided information not only for new cardiac structural and functional indices but also for myocardial deformation with high sensitivity and specificity, making it more useable for various cardiovascular diseases.

This Special Issue of Diagnostics, entitled ‘Advances in Point-of-Care Ultrasonography’, focuses on recent advances in echocardiography techniques and its impact on diagnosis, evaluation of management, and prognosis.

It aims to publish innovative research articles with clinical impact and scientific value, including observational studies, clinical trials, and review articles in various cardiovascular diseases.

Dr. Ibadete Bytyçi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • speckle tracking echocardiography
  • contrast echocardiography
  • three-dimensional echocardiography
  • stress echocardiography
  • transesophageal echocardiography
  • carotid echocardiography
  • myocardial motion and deformation
  • heart structure and function indices

Published Papers (5 papers)

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14 pages, 4181 KiB  
Systematic Review
Assessing the Efficacy of Inferior Vena Cava Collapsibility Index for Predicting Hypotension after Central Neuraxial Block: A Systematic Review and Meta-Analysis
by Ying-Jen Chang, Chien-Cheng Liu, Yen-Ta Huang, Jheng-Yan Wu, Kuo-Chuan Hung, Ping-Hsin Liu, Chien-Hung Lin, Yao-Tsung Lin, I-Wen Chen and Kuo-Mao Lan
Diagnostics 2023, 13(17), 2819; https://doi.org/10.3390/diagnostics13172819 - 31 Aug 2023
Cited by 1 | Viewed by 1152
Abstract
The use of ultrasonography to predict spinal-induced hypotension (SIH) has gained significant attention. This diagnostic meta-analysis aimed to investigate the reliability of the inferior vena cava collapsibility index (IVCCI) in predicting SIH in patients undergoing various surgeries. Databases, including Embase, Cochrane Library, Medline, [...] Read more.
The use of ultrasonography to predict spinal-induced hypotension (SIH) has gained significant attention. This diagnostic meta-analysis aimed to investigate the reliability of the inferior vena cava collapsibility index (IVCCI) in predicting SIH in patients undergoing various surgeries. Databases, including Embase, Cochrane Library, Medline, and Google Scholar, were screened until 28 July 2023, yielding 12 studies with 1076 patients (age range: 25.6–79 years) undergoing cesarean section (CS) (n = 4) or non-CS surgeries (n = 8). Patients with SIH had a significantly higher IVCCI than those without SIH (mean difference: 11.12%, 95% confidence interval (CI): 7.83–14.41). The pooled incidence rate of SIH was 40.5%. IVCCI demonstrated satisfactory overall diagnostic reliability (sensitivity, 77%; specificity, 82%). The pooled area under the curve (AUC) was 0.85, indicating its high capability to differentiate patients at risk of PSH. The Fagan nomogram plot demonstrated a positive likelihood ratio (PLR) of 4 and a negative likelihood ratio (NLR) of 0.28. The results underscore the robustness and discriminative ability of IVCCI as a predictive tool for SIH. Nevertheless, future investigations should focus on assessing its applicability to high-risk patients and exploring the potential enhancement in patient safety through its incorporation into clinical practice. Full article
(This article belongs to the Special Issue Advances in Point-of-Care Ultrasonography)
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6 pages, 469 KiB  
Brief Report
Using a Linear Probe Ultrasound for the Detection of First-Trimester Pregnancies in the Emergency Department
by Soheil Saadat, Michelle Thao Nguyen, Isabelle Nepomuceno, Erinna Thai, Ami Kurzweil, Heesun Choi, Shadi Lahham and John Christian Fox
Diagnostics 2023, 13(15), 2564; https://doi.org/10.3390/diagnostics13152564 - 01 Aug 2023
Viewed by 633
Abstract
Linear probe point-of-care ultrasound (LPUS) presents a less invasive alternative for identifying intrauterine pregnancies (IUPs) compared to usual practice (transabdominal (TAUS) or transvaginal (TVUS) ultrasound). TAUS and TVUS can be invasive or produce lower-resolution images than LPUS. The purpose of this study is [...] Read more.
Linear probe point-of-care ultrasound (LPUS) presents a less invasive alternative for identifying intrauterine pregnancies (IUPs) compared to usual practice (transabdominal (TAUS) or transvaginal (TVUS) ultrasound). TAUS and TVUS can be invasive or produce lower-resolution images than LPUS. The purpose of this study is to determine whether a linear probe alone can identify first-trimester IUPs. A convenience sample of 21 patients were enrolled at the University of California Irvine ED during a 7-month period. The inclusion criteria were English- or Spanish-speaking women (≥18 years) in their first trimester of pregnancy (≤12 weeks pregnant) with a body mass index (BMI) of <35. The exclusion criteria were psychiatric, incarcerated, or cognitively impaired patients. An ED physician performed LPUS and ordered a confirmatory ultrasound. The 21 patients enrolled had a mean age of 28.6 ± 6.60 years, BMI of 26.6 ± 5.03, and gestational age of 7.4 ± 2.69 weeks. Considering the 95% confidence interval, we are 97.5% confident that the sensitivity and specificity of LPUS to identify IUPs does not exceed 67.1% and 93.2%, respectively. Our pilot data did not demonstrate that LPUS can independently visualize IUPs in first-trimester patients. Full article
(This article belongs to the Special Issue Advances in Point-of-Care Ultrasonography)
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15 pages, 7344 KiB  
Systematic Review
Diagnostic Efficacy of Carotid Ultrasound for Predicting the Risk of Perioperative Hypotension or Fluid Responsiveness: A Meta-Analysis
by Kuo-Chuan Hung, Yen-Ta Huang, Wen-Wen Tsai, Ping-Heng Tan, Jheng-Yan Wu, Po-Yu Huang, Ting-Hui Liu, I-Wen Chen and Cheuk-Kwan Sun
Diagnostics 2023, 13(13), 2290; https://doi.org/10.3390/diagnostics13132290 - 06 Jul 2023
Viewed by 1211
Abstract
Despite the acceptance of carotid ultrasound for predicting patients’ fluid responsiveness in critical care and anesthesia, its efficacy for predicting hypotension and fluid responsiveness remains unclear in the perioperative setting. Electronic databases were searched from inception to May 2023 to identify observational studies [...] Read more.
Despite the acceptance of carotid ultrasound for predicting patients’ fluid responsiveness in critical care and anesthesia, its efficacy for predicting hypotension and fluid responsiveness remains unclear in the perioperative setting. Electronic databases were searched from inception to May 2023 to identify observational studies focusing on the use of corrected blood flow time (FTc) and respirophasic variation in carotid artery blood flow peak velocity (ΔVpeak) for assessing the risks of hypotension and fluid responsiveness. Using FTc as a predictive tool (four studies), the analysis yielded a pooled sensitivity of 0.82 (95% confidence interval (CI): 0.72 to 0.89) and specificity of 0.94 (95% CI: 0.88 to 0.97) for the risk of hypotension (area under curve (AUC): 0.95). For fluid responsiveness, the sensitivity and specificity of FTc were 0.79 (95% CI: 0.72 to 0.84) and 0.81 (95% CI: 0.75 to 0.86), respectively (AUC: 0.87). In contrast, the use of ΔVpeak to predict the risk of fluid responsiveness showed a pooled sensitivity of 0.76 (95% CI: 0.63 to 0.85) and specificity of 0.74 (95% CI: 0.66 to 0.8) (AUC: 0.79). The current meta-analysis provides robust evidence supporting the high diagnostic accuracy of FTc in predicting perioperative hypotension and fluid responsiveness, which requires further studies for verification. Full article
(This article belongs to the Special Issue Advances in Point-of-Care Ultrasonography)
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14 pages, 591 KiB  
Systematic Review
Ultrasound Elastography to Assess Age of Deep Vein Thrombosis: A Systematic Review
by Paolo Santini, Giorgio Esposto, Maria Elena Ainora, Andrea Lupascu, Antonio Gasbarrini, Maria Assunta Zocco and Roberto Pola
Diagnostics 2023, 13(12), 2075; https://doi.org/10.3390/diagnostics13122075 - 15 Jun 2023
Cited by 4 | Viewed by 1012
Abstract
Background and aims: Deep-vein thrombosis (DVT) is a widely diffused condition, and its accurate staging has major clinical and therapeutic implications. Ultrasound elastography (UE) is a rapidly evolving imaging technique that allows quantification of elastic tissue properties and could play a crucial role [...] Read more.
Background and aims: Deep-vein thrombosis (DVT) is a widely diffused condition, and its accurate staging has major clinical and therapeutic implications. Ultrasound elastography (UE) is a rapidly evolving imaging technique that allows quantification of elastic tissue properties and could play a crucial role in determining thrombus age. The aim of this review is to find clinical evidence regarding the application of UE in the evaluation of DVT and its usefulness in differentiating thrombosis age. Methods: A literature search of clinical studies was performed to identify the ability of UE of discriminate acute, subacute, and chronic DVT. Heterogeneity and publication bias were calculated. In accordance with the study protocol, a qualitative analysis of the evidence was planned. The results were summarized with a comprehensive summary table of study characteristics and baseline characteristics of participant patients. Results: Nine studies matched the predetermined eligibility requirements for this systematic review regarding the risk of bias; the greatest criticalities were found within the domains of patient selection and index test. Based on the quality assessment, two publications were excluded from the qualitative synthesis because of the presence of significant applicability concerns. Among the seven studies that were considered eligible for qualitative synthesis, four evaluated strain elastography and three evaluated shear-wave elastography. Despite significant differences concerning study design, thrombus age definitions, and patient characteristics, nearly all studies demonstrated an increase in thrombus stiffness according to DVT age. Conclusions: UE could play a key role in routine ultrasound examination of DVT. The measurement of thrombus stiffness has a high biological plausibility and its use is supported by the finding of a correlation between the stiffness and the progression of the DVT age. Full article
(This article belongs to the Special Issue Advances in Point-of-Care Ultrasonography)
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11 pages, 705 KiB  
Guidelines
Thoracic UltrasONOgraphy Reporting: The TUONO Consensus
by Italo Calamai, Massimiliano Greco, Marzia Savi, Gaia Vitiello, Elena Garbero, Rosario Spina, Luigi Pisani, Silvia Mongodi, Stefano Finazzi and on behalf of the TUONO Study Investigators
Diagnostics 2023, 13(9), 1535; https://doi.org/10.3390/diagnostics13091535 - 25 Apr 2023
Cited by 1 | Viewed by 1339
Abstract
The widespread use of the lung ultrasound (LUS) has not been followed by the development of a comprehensive standardized tool for its reporting in the intensive care unit (ICU) which could be useful to promote consistency and reproducibility during clinical examination. This work [...] Read more.
The widespread use of the lung ultrasound (LUS) has not been followed by the development of a comprehensive standardized tool for its reporting in the intensive care unit (ICU) which could be useful to promote consistency and reproducibility during clinical examination. This work aims to define the essential features to be included in a standardized reporting tool and provides a structured model form to fully express the diagnostic potential of LUS and facilitate intensivists in the use of a LUS in everyday clinical ICU examination. We conducted a modified Delphi process to build consensus on the items to be integrated in a standardized report form and on its structure. A committee of 19 critical care physicians from 19 participating ICUs in Italy was formed, including intensivists experienced in ultrasound from both teaching hospitals and referral hospitals, and internationally renowned experts on the LUS. The consensus for 31 statements out of 33 was reached at the third Delphi round. A structured model form was developed based on the approved statements. The development of a standardized model as a backbone to report a LUS may facilitate the guidelines’ application in clinical practice and increase inter-operator agreement. Further studies are needed to evaluate the effects of standardized reports in critically ill patients. Full article
(This article belongs to the Special Issue Advances in Point-of-Care Ultrasonography)
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