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Diagnostics
Special Issues
Diagnosis and Management of Liver Diseases and Inflammatory Bowel Diseases
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Diagnosis and Management of Liver Diseases and Inflammatory Bowel Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 864

Special Issue Editors

Dr. Milica Stojković-Lalošević

E-Mail Website
Guest Editor
1. Faculty of Medicine Belgrade, University of Belgrade, 11000 Belgrade, Serbia
2. Clinic for Gastroenterohepatology, University Clinical Centre of Serbia, 11000 Belgrade, Serbia
Interests: Crohn's disease; ulcerative colitis; hepatitis; cholangitis
Dr. Sanja Dragašević

E-Mail Website
Guest Editor
1. Faculty of Medicine Belgrade, University of Belgrade, 11000 Belgrade, Serbia
2. Clinic for Gastroenterohepatology, University Clinical Centre of Serbia, 11000 Belgrade, Serbia
Interests: gastroenterology; hepatology

Special Issue Information

Dear Colleagues,

The global burden of liver and inflammatory bowel diseases is on the rise. Although complex pathophysiological mechanisms of various liver disorders as well as inflammatory bowel disease have been elucidated, morbidity is still high. Although breakthroughs in diagnosing metabolic-dysfunction-associated steatosis liver disease, primary sclerosing cholangitis, primary biliary cholangitis, hepatitis B and C, and autoimmune hepatitis have been made in recent decades, the adequate timing of diagnosis, and hence treatment, still remains a clinical challenge. Taking into consideration that liver disease in some cases may accompany inflammatory bowel disease, it is of great importance to diagnose both conditions properly so that the management of these diseases can commence in a timely and adequate manner.

In this Special Issue, new, original research articles and reviews regarding the diagnosis and management of liver and inflammatory bowel diseases, as well as complications and special conditions related to these diseases, will be considered for publication.

Dr. Milica Stojković-Lalošević
Dr. Sanja Dragašević
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • liver disease
  • complications
  • inflammatory bowel disease
  • liver cirrhosis
  • MASLD
  • pregnancy
  • skin disorders

Published Papers (2 papers)

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Research

11 pages, 462 KiB  
Article
Influence of Achalasia on the Spirometry Flow–Volume Curve and Peak Expiratory Flow
by Jelena Jankovic, Branislava Milenkovic, Aleksandar Simic, Ognjan Skrobic, Arschang Valipour, Nenad Ivanovic, Ivana Buha, Jelena Milin-Lazovic, Natasa Djurdjevic, Aleksandar Jandric, Nikola Colic, Stefan Stojkovic and Mihailo Stjepanovic
Diagnostics 2024, 14(9), 933; https://doi.org/10.3390/diagnostics14090933 - 29 Apr 2024
Viewed by 139
Abstract
Background: Achalasia is an esophageal motor disorder characterized by aperistalsis and the failure of the relaxation of the lower esophageal sphincter. We want to find out whether external compression or recurrent micro-aspiration of undigested food has a functional effect on the airway. Methods: [...] Read more.
Background: Achalasia is an esophageal motor disorder characterized by aperistalsis and the failure of the relaxation of the lower esophageal sphincter. We want to find out whether external compression or recurrent micro-aspiration of undigested food has a functional effect on the airway. Methods: The aim of this research was to analyze the influence of achalasia on the peak expiratory flow and flow–volume curve. All of the 110 patients performed spirometry. Results: The mean diameter of the esophagus was 5.4 ± 2.1 cm, and nine of the patients had mega-esophagus. Seven patients had a plateau in the inspiratory part of the flow–volume curve, which coincides with the patients who had mega-esophagus. The rest of the patients had a plateau in the expiration part of the curve. The existence of a plateau in the diameter of the esophagus of more than 5 cm was significant (p 0.003). Statistical significance between the existence of a plateau and a lowered PEF (PEF < 80) has been proven (p 0.001). Also, a statistical significance between the subtype and diameter of more than 4 cm has been proved. There was no significant improvement in the PEF values after operation. In total, 20.9% of patients had a spirometry abnormality finding. The frequency of the improvement in the spirometry values after surgery did not differ significantly by achalasia subtype. The improvement in FEV1 was statistically significant compared to the FVC values. Conclusions: Awareness of the influence of achalasia on the pulmonary parameters is important because low values of PEF with a plateau on the spirometry loop can lead to misdiagnosis. The recognition of various patterns of the spirometry loop may help in identifying airway obstruction caused by another non-pulmonary disease such as achalasia. Full article
(This article belongs to the Special Issue Diagnosis and Management of Liver Diseases and Inflammatory Bowel Diseases)
21 pages, 2778 KiB  
Article
Could Capsule Endoscopy Be Useful in Detection of Suspected Small Bowel Bleeding and IBD-10 Years of Single Center Experience
by Jelena Martinov Nestorov, Aleksandra Sokic-Milutinovic, Aleksandra Pavlovic Markovic and Miodrag Krstic
Diagnostics 2024, 14(9), 862; https://doi.org/10.3390/diagnostics14090862 - 23 Apr 2024
Viewed by 312
Abstract
A retrospective study in patients who underwent video capsule endoscopy (VCE) between 2006 and 2016 was conducted in the Clinic for gastroenterology and Hepatology, University Clinical Center of Serbia. A total of 245 patients underwent VCE. In 198 patients the indication was obscure [...] Read more.
A retrospective study in patients who underwent video capsule endoscopy (VCE) between 2006 and 2016 was conducted in the Clinic for gastroenterology and Hepatology, University Clinical Center of Serbia. A total of 245 patients underwent VCE. In 198 patients the indication was obscure gastrointestinal bleeding (OGIB), with 92 patients having overt and the other 106 occult bleeding. The remaining 47 patients underwent VCE due to suspected small bowel (SB) disease (i.e., Von Hippel–Lindau syndrome, familial adenomatous polyposis, Peutz Jeghers syndrome, Crohn’s disease, prolonged diarrhea, abdominal pain, congenital lymphangiectasia, protein-losing enteropathy, tumors, refractory celiac disease, etc.). VCE identified a source of bleeding in 38.9% of patients (in the obscure overt group in 48.9% of patients, and in the obscure occult group in 30.2% of patients). The most common findings were angiodysplasias, tumors, Meckel’s diverticulum and Crohn’s disease. In the smaller group of patients with an indication other than OGIB, 38.3% of patients had positive VCE findings. The most common indication is OGIB, and the best candidates are patients with overt bleeding; patients with IBD should be evaluated in this setting. Full article
(This article belongs to the Special Issue Diagnosis and Management of Liver Diseases and Inflammatory Bowel Diseases)
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