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Diagnostics
Special Issues
Diagnosis, Treatment and Management of Eye Diseases, Second Edition
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Diagnosis, Treatment and Management of Eye Diseases, Second Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Optical Diagnostics".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1970

Special Issue Editors

Dr. Ştefan Cristian Vesa

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Guest Editor
Department of Pharmacology, Clinical Pharmacology and Toxicology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
Interests: pharmacology; doppler ultrasound; pharmacogenetics
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Simona Delia Nicoara

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Guest Editor
1. Department of Ophthalmology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
2. Emergency County Hospital, 400006 Cluj-Napoca, Romania
Interests: vitreo-retinal surgery; medical retina; retinopathy of prematurity; artificial intelligence in retinal disease; stem cells; genetics in ophthalmology
Special Issues, Collections and Topics in MDPI journals
Dr. Claudia Florida Costea

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Guest Editor
1. Department of Ophthalmology, “Gr.T.Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
2. “Prof. Dr. Nicolae Oblu” Emergency Clinical Hospital, 700309 Iasi, Romania
Interests: neuro-ophthalmology; orbit disease; cataract surgery; medical retina
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, significant progress has been achieved in the diagnosis and management of eye diseases. Optical coherence tomography, progress in ophthalmic surgical technology, gene therapy, regenerative cellular therapies, nanotechnology, development of new molecules to target various ocular tissues and pathogenetic mechanisms, and artificial intelligence offer new tools to diagnose and treat ocular diseases in a multidisciplinary approach. This Special Issue focuses on the methods currently available to diagnose and treat various eye conditions, with a view to future developments and their potential to improve ophthalmological care. Original articles and reviews from all subspecialties of ophthalmology are welcome, with an emphasis on recent advances in diagnosis and therapy. The goal of this Special Issue is to publish articles from clinical, but also from experimental research with an impact on the diagnosis and treatment of eye diseases with a multidisciplinary approach.

Dr. Ştefan Cristian Vesa
Prof. Dr. Simona Delia Nicoara
Dr. Claudia Florida Costea
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • optical coherence tomography
  • artificial intelligence
  • gene therapy
  • nanotechnology
  • stem cells
  • vitreo-retinal surgery
  • corneal transplantation
  • minimally invasive glaucoma surgery
  • cataract surgery
  • retinopathy of prematurity

Published Papers (2 papers)

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Research

18 pages, 1417 KiB  
Article
Possibility of Using Surgical Pleth Index in Predicting Postoperative Pain in Patients after Vitrectomy Performed under General Anesthesia
by Michał Jan Stasiowski, Anita Lyssek-Boroń, Magdalena Kawka-Osuch, Ewa Niewiadomska and Beniamin Oskar Grabarek
Diagnostics 2024, 14(4), 425; https://doi.org/10.3390/diagnostics14040425 - 14 Feb 2024
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Abstract
Adequacy of anesthesia concept (AoA) in the guidance of general anesthesia (GA) is based on entropy, and it also reflects the actual depth of anesthesia and the surgical pleth index (SPI). Therefore, this study aimed to analyze the potential existence of relationships between [...] Read more.
Adequacy of anesthesia concept (AoA) in the guidance of general anesthesia (GA) is based on entropy, and it also reflects the actual depth of anesthesia and the surgical pleth index (SPI). Therefore, this study aimed to analyze the potential existence of relationships between SPI values at certain stages of the AoA-guided GA for vitreoretinal surgeries (VRS) and the incidence of intolerable postoperative pain perception (IPPP). A total of 175 patients were each assigned to one of five groups. In the first, the VRS procedure was performed under GA without premedication; in the second group, patients received metamizole before GA; in the third, patients received acetaminophen before GA; in the fourth group, patients received Alcaine before GA; and, in the peribulbar block group, the patients received a peribulbar block with a mix of the solutions of lignocaine and bupivacaine. Between the patients declaring mild and statistically significant differences in the IPPP in terms of SPI values before induction (52.3 ± 18.8 vs. 63.9 ± 18.1, p < 0.05) and after emergence from GA (51.1 ± 13 vs. 68.1 ± 8.8; p < 0.001), it was observed that the patients postoperatively correlated with heart rate variations despite the group allocation. The current study proves the feasibility that preoperative SPI values help with predicting IPPP immediately after VRS under AoA guidance and discrimination (between mild diagnoses and IPPP when based on postoperative SPI values) as they correlate with heart rate variations. Specifically, this applies when the countermeasures of IPPP and hemodynamic fluctuations are understood to be of importance in reducing unwelcome adverse events. Full article
(This article belongs to the Special Issue Diagnosis, Treatment and Management of Eye Diseases, Second Edition)
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12 pages, 653 KiB  
Article
Eye Pain Caused by Epithelial Damage in the Central Cornea in Aqueous-Deficient Dry Eye
by Yamato Yoshikawa, Norihiko Yokoi, Natsuki Kusada, Hiroaki Kato, Rieko Sakai, Aoi Komuro, Yukiko Sonomura and Chie Sotozono
Diagnostics 2024, 14(1), 30; https://doi.org/10.3390/diagnostics14010030 - 22 Dec 2023
Viewed by 567
Abstract
In this study, the severity of eye pain (EP) and associated objective findings were evaluated in aqueous-deficient dry eye (ADDE) patients using PainVision®, a quantitative pain-measuring device. This study involved 53 eyes of 53 ADDE patients (6 males and 47 females; [...] Read more.
In this study, the severity of eye pain (EP) and associated objective findings were evaluated in aqueous-deficient dry eye (ADDE) patients using PainVision®, a quantitative pain-measuring device. This study involved 53 eyes of 53 ADDE patients (6 males and 47 females; mean age: 64.4 ± 13.4 [mean ± SD] years). Of those, 18 eyes of 18 patients underwent punctal occlusion, and EP and objective findings in those patients were evaluated before and after treatment. In all patients, the severity of EP as measured by PainVision® was assessed using the Pain Degree (PD). The median PD for the 53 patients was 30.6 µA/µA (interquartile range, 16.9–93.2), and the nasal and central corneal staining score and the upper lid-wiper epitheliopathy score were significantly correlated with PD (R = 0.33, 0.33, and 0.28, respectively) (all: p < 0.05). Using the least squares method, the central corneal staining score most significantly affected PD. In the 18 cases that underwent punctal occlusion, PD was significantly reduced (median PD: 24.8 to 7.1 µA/µA; p < 0.0001). Using the least squares method, the central corneal staining score and tear meniscus radius were significantly more influential as factors contributing to PD before and after treatment, and central corneal epithelial damage was the factor most associated with ADDE-related EP. Full article
(This article belongs to the Special Issue Diagnosis, Treatment and Management of Eye Diseases, Second Edition)
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