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Diagnostics
Special Issues
New Perspectives of Digestive Endoscopy for Diagnosing Biliopancreatic Diseases
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New Perspectives of Digestive Endoscopy for Diagnosing Biliopancreatic Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1002

Special Issue Editors

Dr. Maria Cristina Conti-Bellocchi

E-Mail Website
Guest Editor
Diagnostic and Interventional Endoscopy of Pancreas, GB Rossi University Hospital, Pancreas Institute, University of Verona, 37134 Verona, Italy
Interests: EUS; biliopancreatic disease; autoimmune pancreatitis; pancreatic cysts; ERCP
Dr. Antonio Amodio

E-Mail Website
Guest Editor
Department of Medicine, Gastroenterology Unit, Pancreas Institute, University of Verona, 37134 Verona, Italy
Interests: acute pancreatitis; chronic pancreatitis; pancreatic cysts; CAPH

Special Issue Information

Dear Colleagues,

We are now serving as the Guest Editor of the Special Issue "New Perspectives of Digestive Endoscopy for Diagnosing Biliopancreatic Diseases" for Diagnostics (impact factor of 3.992), which is an open access journal.

This Special Issue aims to summarize the most recent advances in the diagnosis of biliopancreatic disease. In this Special Issue, original research articles and reviews are welcome. Research areas may include the various diagnostic approaches and management of biliary and pancreatic diseases, including (but not limited to) endoscopy.

Please do not hesitate to contact us or the Editorial Office (gracie.zhang@mdpi.com) for further information. We look forward to receiving your contributions.

Dr. Maria Cristina Conti-Bellocchi
Dr. Antonio Amodio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endoscopic ultrasound
  • fine-needle biopsy
  • ERCP
  • cholangioscopy
  • pancreatic cancer
  • pancreatic cysts
  • autoimmune pancreatitis
  • acute pancreatitis
  • chronic pancreatitis
  • cholangiocarcinoma

Published Papers (1 paper)

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Research

15 pages, 1977 KiB  
Article
EUS-FNA versus EUS-FNB in Pancreatic Solid Lesions ≤ 15 mm
by Maria Cristina Conti Bellocchi, Micol Bernuzzi, Alessandro Brillo, Laura Bernardoni, Antonio Amodio, Nicolò De Pretis, Luca Frulloni, Armando Gabbrielli and Stefano Francesco Crinò
Diagnostics 2024, 14(4), 427; https://doi.org/10.3390/diagnostics14040427 - 15 Feb 2024
Viewed by 740
Abstract
A small tumor size may impact the diagnostic performance of endoscopic ultrasound-guided tissue acquisition (EUS-TA) for diagnosing solid pancreatic lesions (SPLs). We aimed to compare the diagnostic yield of EUS-guided fine-needle aspiration (FNA) and biopsy (FNB) in SPLs with a diameter ≤ 15 [...] Read more.
A small tumor size may impact the diagnostic performance of endoscopic ultrasound-guided tissue acquisition (EUS-TA) for diagnosing solid pancreatic lesions (SPLs). We aimed to compare the diagnostic yield of EUS-guided fine-needle aspiration (FNA) and biopsy (FNB) in SPLs with a diameter ≤ 15 mm. Consecutive patients who underwent EUS-TA for SPLs ≤ 15 mm between January 2015 and December 2022 in a tertiary referral center were retrospectively evaluated. The primary endpoint was diagnostic accuracy. The final diagnosis was based on surgical pathology or disease evolution after a minimum follow-up of 6 months. Inadequate samples were all considered false negatives for the study. Secondary outcomes included sample adequacy, factors impacting accuracy, and safety. We included 368 patients (52.4% male; mean age: 60.2 years) who underwent FNA in 72 cases and FNB in 296. The mean size of SPLs was 11.9 ± 2.6 mm. More than three passes were performed in 5.7% and 61.5% of patients in the FNB and FNA groups, respectively (p < 0.0001). FNB outperformed FNA in terms of diagnostic accuracy (89.8% vs. 79.1%, p = 0.013) and sample adequacy (95.9% vs. 86.1%, p < 0.001). On multivariate analysis, using FNA (OR: 2.10, 95% CI: 1.07–4.48) and a final diagnosis (OR: 3.56, 95% CI: 1.82–6.94) of benign conditions negatively impacted accuracy. Overall, the adverse event rate was 0.8%, including one pancreatitis in the FNA group and one pancreatitis and one bleeding in the FNB group, all mild and conservatively managed. EUS-TA for SPLs ≤ 15 mm has a high diagnostic yield and safety. This study suggests the superiority of FNB over FNA, with better performance even with fewer passes performed. Full article
(This article belongs to the Special Issue New Perspectives of Digestive Endoscopy for Diagnosing Biliopancreatic Diseases)
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