Imaging of Fetal and Maternal Diseases in Pregnancy: 3rd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 967

Special Issue Editor

Special Issue Information

Dear Colleagues,

Ultrasound (US) is a standard approach for the initial evaluation of fetal anatomy and maternal conditions during pregnancy, allowing for a real-time examination, and is widely available and cost-effective.

In recent years, magnetic resonance (MR) has become a useful element in the decision-making process for fetal abnormalities and maternal diseases in pregnancy, proving to offer unequivocal advantages over ultrasound.

The primary goals of this Special Issue are to describe the state-of-the-art imaging techniques for pregnant patients presenting with fetal or maternal diseases, discuss the morphological and functional information provided by US and MR that is useful in management and guiding therapy, and present new research developments in the field of prenatal imaging.

Dr. Gabriele Masselli
Guest Editor

Manuscript Submission Information

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Keywords

  • fetal
  • MRI
  • US
  • placenta
  • pregnancy
  • maternal diseases
  • imaging
  • surgery
  • obstetrics

Published Papers (1 paper)

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Research

11 pages, 717 KiB  
Article
Stratifying Antenatal Hydronephrosis: Predicting High-Grade VUR Using Ultrasound and Scintigraphy
by Niklas Pakkasjärvi, Sofia Belov, Timo Jahnukainen, Reetta Kivisaari and Seppo Taskinen
Diagnostics 2024, 14(4), 384; https://doi.org/10.3390/diagnostics14040384 - 09 Feb 2024
Viewed by 745
Abstract
(1) Background: Antenatal hydronephrosis (AHN), detected in approximately one percent of prenatal ultrasounds, is caused by vesicoureteral reflux (VUR) in 15–21% of cases, a condition with significant risks such as urinary tract infections and renal scarring. Our study addresses the diagnostic challenges of [...] Read more.
(1) Background: Antenatal hydronephrosis (AHN), detected in approximately one percent of prenatal ultrasounds, is caused by vesicoureteral reflux (VUR) in 15–21% of cases, a condition with significant risks such as urinary tract infections and renal scarring. Our study addresses the diagnostic challenges of VUR in AHN. Utilizing renal ultrasonography and scintigraphy, we developed a novel scoring system that accurately predicts high-grade VUR, optimizing diagnostic precision while minimizing the need for more invasive methods like voiding cystourethrogram (VCUG); (2) Methods: This retrospective study re-analyzed renal ultrasonography, scintigraphy, and VCUG images from infants admitted between 2003 and 2013, excluding cases with complex urinary anomalies; (3) Results: Our analysis included 124 patients (75% male), of whom 11% had high-grade VUR. The multivariate analysis identified visible ureter, reduced renal length, and decreased differential renal function (DRF) as primary predictors. Consequently, we established a three-tier risk score, classifying patients into low, intermediate, and high-risk groups for high-grade VUR, with corresponding prevalences of 2.3%, 22.2%, and 75.0%. The scoring system demonstrated 86% sensitivity and 79% specificity; (4) Conclusions: Our scoring system, focusing on objective parameters of the visible ureter, renal length, and DRF, effectively identifies high-grade VUR in AHN patients. This method enhances diagnostics in ANH by reducing reliance on VCUG and facilitating more tailored and less invasive patient care. Full article
(This article belongs to the Special Issue Imaging of Fetal and Maternal Diseases in Pregnancy: 3rd Edition)
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