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Diagnostics
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Advances in Head and Neck Ultrasound
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Advances in Head and Neck Ultrasound

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 5876

Special Issue Editors

Dr. Tobias Todsen

E-Mail Website
Guest Editor
Associate Professor, Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark
Interests: point-of-care ultrasound; otolaryngology - head and neck surgery
Prof. Dr. Lisa A. Orloff

E-Mail Website
Guest Editor
Department of Otolaryngology, Division of Head and Neck Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, USA
Interests: thyroid cancer; ultrasonography; laryngeal surgery; otolaryngology
Prof. Dr. Sebelik Merry

E-Mail Website
Guest Editor
Department of Otolaryngology, Head and Neck Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
Interests: otolaryngology; head and neck surgery

Special Issue Information

Dear Colleagues,

Clinician-performed head and neck ultrasounds are expanding to office-based and surgical settings to improve the diagnostic work-up and surgical results. Furthermore, minimally invasive treatments, e.g., radiofrequency ablation and ethanol injections of thyroid cysts, are increasingly used instead of surgery. This Special Issue will cover new advancements in diagnostic head and neck ultrasound and ultrasound-guided interventions. The issue will cover all aspects from ultrasound education, the clinical impact of surgeon-performed ultrasound, the validation of new ultrasound scanning techniques/areas, advanced ultrasound technologies (contrast-enhanced ultrasound, elastography, 3D ultrasound, super-resolution imaging, etc.), and ultrasound-guided minimally invasive treatments.

Dr. Tobias Todsen
Prof. Dr. Lisa A. Orloff
Prof. Dr. Sebelik Merry
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • head and neck ultrasound
  • thyroid and parathyroid ultrasound
  • multiparametric ultrasound
  • surgeon-performed ultrasound
  • perioperative ultrasound
  • ultrasound-guided interventions
  • radiofrequency ablation (RFA)
  • minimally invasive techniques

Published Papers (4 papers)

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Research

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11 pages, 900 KiB  
Article
Comparison of Arterial Stiffness and Strain Measured with Speckle Tracking Carotid Strain Ultrasonography after Radiation and Surgical Treatment for Head and Neck Cancer—A Clinical Trial
by Bengu Depboylu, Aylin Eryilmaz, Hatice Sema Basak, Veli Kirbac, Yesim Basal, Imran Kurt Omurlu and Mustafa Gok
Diagnostics 2023, 13(19), 3090; https://doi.org/10.3390/diagnostics13193090 - 29 Sep 2023
Viewed by 713
Abstract
This study assessed arterial stiffness in head and neck cancer patients using speckle tracking carotid strain ultrasonography (STCS-US). It investigated the impacts of neck irradiation and neck dissection on the arterial stiffness of these patients by comparing their stiffness parameters with those of [...] Read more.
This study assessed arterial stiffness in head and neck cancer patients using speckle tracking carotid strain ultrasonography (STCS-US). It investigated the impacts of neck irradiation and neck dissection on the arterial stiffness of these patients by comparing their stiffness parameters with those of healthy controls. A total of 101 participants (67 patients and 34 healthy controls) were enrolled in this study. Fifty-two patients received definitive radiation therapy (TD: 60–72 Gy in 30 days) at least two years ago. Participants were grouped into four according to their states of neck irradiation (IR) and neck dissection (ND): Group (IR+/ND−) had 28 patients, Group (IR+/ND+) had 24 patients, Group (IR−/ND+) had 15 patients, and Group (IR−/ND−) had 34 healthy controls. All the participants underwent STCS-US. Arterial stiffness parameters relating to arterial compliance (AC) and elastic modulus (EM) were significantly changed in Group (IR+/ND−) and Group (IR+/ND+) in the transverse plane (p < 0.001, p < 0.001) and in the longitudinal plane (p < 0.001, p < 0.001); the change in β-stiffness index (β-SI) was more significant in the transverse plane (p = 0.002). Group (IR+/ND+) had significant transverse circumferential (p = 0.001) and radial strain parameters (p = 0.001). The carotid intimal medial thickness (CIMT) significantly changed in Group (IR+/ND+) compared to controls (p = 0.001). Our findings indicate that neck irradiation and neck dissection increase arterial stiffness as single treatments; however, double treatment is associated with a higher increase. Neck irradiation affects strain parameters more than neck dissection alone. The study demonstrated the feasibility and clinical value of the STCS method in assessing arterial stiffness and its potential use in cardiovascular risk assessment for patients with head and neck cancer. Full article
(This article belongs to the Special Issue Advances in Head and Neck Ultrasound)
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16 pages, 2165 KiB  
Article
Diagnostic Performance of ACR TI-RADS and ATA Guidelines in the Prediction of Thyroid Malignancy: A Prospective Single Tertiary Center Study and Literature Review
by Ashkan Torshizian, Fatemeh Hashemi, Nastaran Khoshhal, Alireza Ghodsi, Houra Rastegar, Zohreh Mousavi, Maliheh Dadgar Moghadam and Masoud Mohebbi
Diagnostics 2023, 13(18), 2972; https://doi.org/10.3390/diagnostics13182972 - 18 Sep 2023
Viewed by 1930
Abstract
Aim: This study sought to compare two common risk stratification systems in terms of their diagnostic performance for the evaluation of thyroid malignancy. Methods: The American College of Radiology (ACR) Thyroid Imaging, Reporting and Data System (TI-RADS) and the American Thyroid Association (ATA) [...] Read more.
Aim: This study sought to compare two common risk stratification systems in terms of their diagnostic performance for the evaluation of thyroid malignancy. Methods: The American College of Radiology (ACR) Thyroid Imaging, Reporting and Data System (TI-RADS) and the American Thyroid Association (ATA) guidelines were compared among 571 thyroid nodules with definitive fine needle aspiration (FNA) cytology or postoperative histopathology. Ultrasound characteristics such as composition, echogenicity, shape, margin, size, and vascularity were assessed for each thyroid nodule. Diagnostic performance measures were determined and compared through receiver operating characteristic (ROC) curves, and decision curve analysis (DCA). Results: Of 571 nodules, 65 (11.4%) were malignant. The AUC, sensitivity, specificity, positive predictive value, and negative predictive value were 0.691, 49.2%, 84.9%, 29.6%, and 92.8% for ATA guideline, and 0.776, 72.3%, 79.2%, 30.9%, and 95.7%, for ACR TI-RADS, respectively. ACR TI-RADS was more sensitive (p = 0.003), while the ATA guideline was more specific (p < 0.001). DCA demonstrated that the ACR TI-RADS provided a greater net benefit than the ATA guideline. In addition, the net reduction in unnecessary biopsies is higher for ACR TI-RADS than ATA guidelines. The total number of indicated biopsies and unnecessary FNA rates were lower in ACR TI-RADS compared to ATA guideline (293 vs. 527 and 80.2 vs. 87.8). ACR TI-RADS presented no biopsy indication in seven malignant nodules (all categorized as TR2), whereas ATA guideline missed one. Hypoechogenicity was the most significant predictor of malignancy (OR = 8.34, 95% CI: 3.75–19.45), followed by a taller-than-wide shape (OR = 6.73, 95% CI: 3.07–14.77). Conclusions: Our findings suggest that each system has particular advantages in the evaluation of thyroid nodules. ACR TI-RADS reduces unnecessary FNA rates, however, malignant nodules categorized as TR2 might be missed using this system. Further evaluation of this group of nodules using Doppler and other ultrasound modalities is recommended. Full article
(This article belongs to the Special Issue Advances in Head and Neck Ultrasound)
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11 pages, 1610 KiB  
Article
Ultrasound Is Beneficial to Determine Lymphadenopathy in Oral Cancer Patients after Radiotherapy
by Ping-Chia Cheng, Chih-Ming Chang, Li-Jen Liao, Chen-Hsi Hsieh, Pei-Wei Shueng, Po-Wen Cheng and Wu-Chia Lo
Diagnostics 2023, 13(14), 2409; https://doi.org/10.3390/diagnostics13142409 - 19 Jul 2023
Viewed by 1408
Abstract
The present study aimed to investigate whether the addition of ultrasound (US) +/− fine needle aspiration (FNA) to magnetic resonance imaging (MRI) or computed tomography (CT) improves the diagnostic accuracy in assessing neck lymphadenopathy in oral cancer patients after neck irradiation. We retrospectively [...] Read more.
The present study aimed to investigate whether the addition of ultrasound (US) +/− fine needle aspiration (FNA) to magnetic resonance imaging (MRI) or computed tomography (CT) improves the diagnostic accuracy in assessing neck lymphadenopathy in oral cancer patients after neck irradiation. We retrospectively reviewed oral cancer patients who had neck lymphadenopathy after radiotherapy (RT) or chemoradiation therapy (CRT) from February 2008 to November 2019. The following diagnostic modalities were assessed: (1) MRI/CT, (2) MRI/CT with a post-RT US predictive model, and (3) MRI/CT with US + FNA. The receiver operating characteristic (ROC) curves were used to assess the diagnostic performance. A total of 104 irradiation-treated oral cancer patients who subsequently had neck lymphadenopathy were recruited and analyzed. Finally, there were 68 (65%) malignant and 36 (35%) benign lymphadenopathies. In terms of the diagnostic performance, the area under the ROC curves (C-statistics) was 0.983, 0.920, and 0.828 for MRI/CT with US + FNA, MRI/CT with a post-RT US predictive model, and MRI/CT, respectively. The addition of US to MRI/CT to evaluate cervical lymphadenopathy could achieve a better diagnostic accuracy than MRI/CT alone in oral cancer patients after neck irradiation. Full article
(This article belongs to the Special Issue Advances in Head and Neck Ultrasound)
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4 pages, 1825 KiB  
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How Soda Ingestion Facilitates the Distinction between a Killian–Jamieson Diverticulum and a Malignant Thyroid Nodule
by Tsung-Jung Liang, Shiuh-Inn Liu and Chia-Ling Chiang
Diagnostics 2023, 13(19), 3128; https://doi.org/10.3390/diagnostics13193128 - 05 Oct 2023
Viewed by 885
Abstract
A 66-year-old woman presented with an incidental left thyroid nodule during a health examination. She had no voice change, shortness of breath, cough, or dysphagia. Repeated sonography showed a dynamic change of the lesion, which was more evident following soda consumption. A subsequent [...] Read more.
A 66-year-old woman presented with an incidental left thyroid nodule during a health examination. She had no voice change, shortness of breath, cough, or dysphagia. Repeated sonography showed a dynamic change of the lesion, which was more evident following soda consumption. A subsequent esophagography confirmed the diagnosis of a Killian–Jamieson diverticulum. This rare left-sided pharyngoesophageal diverticulum is often asymptomatic. On a sonography, air bubbles in the esophageal lumen can cause a ring-down artifact that mimics microcalcifications, which are characteristic of thyroid malignancy, and misdiagnosis may lead to unnecessary interventions, including fine-needle aspiration or thyroidectomy. A dynamic ultrasound, specifically done during soda consumption, offered a simple diagnostic distinction. No surgical intervention was pursued; the patient was monitored in the clinic. Full article
(This article belongs to the Special Issue Advances in Head and Neck Ultrasound)
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