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Advances in Electrochemical Sensors and Biosensors
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Advances in Electrochemical Sensors and Biosensors

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 7258

Special Issue Editor

Dr. Kamila Malecka-Baturo

E-Mail Website
Guest Editor
Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Biosensors Department, Tuwima Str. 10, 10-748 Olsztyn, Poland
Interests: electrochemical sensors and biosensors; redox-active layers; biomedical diagnosis

Special Issue Information

Dear Colleagues,

In recent decades, much attention has been paid to the development of electrochemical sensors and biosensors, providing remarkable features such as fast response, handling ease, robust, cost-effectivity sensitivity, portability, simplicity of design, ease of miniaturizing, and low sample volume. The commonly observed interest in this group of sensors results from the relatively low production and operating costs as well as good metrological and operational parameters. The signal of their response is a change in current, or potential, which provides wide possibilities of further advanced signal processing at the analogue level. The versatility of these tools ensures a broad spectrum in the sensing of biological and chemical analytes in respect of electrochemical change of electrode/electrolyte interfacial characteristics. The advantage of biosensors over traditional analytical methods will certainly lead to their even greater use in environmental monitoring food safety, medicine, including clinical diagnostics or monitoring and control of industrial processes in the near future.

The selection of the working electrode material and its appropriate modification play a crucial role in the development of sensitive electrochemical platforms for the detection of target molecules. Progress is constantly being observed with the implementation of new advanced platforms for the design of biosensors, such as graphene, carbon nanotubes or nanofibers, nanoclusters, nanoparticles, etc. Due to outstanding advances in nanotechnology, nanomaterial-based signal amplification strategies have an enormous impact on improving parameters such as sensitivity and selectivity of electrochemical sensors and biosensors. The optimal signal amplification strategy can increase the intensity of its response several times.

We are pleased to invite you to broaden the field of electrochemical sensors and biosensors, describing fundamentals and application of sensor technology.

This Special Issue aims to focus on advances in electrochemical sensors and biosensors: the novel strategies in their development technology, future trends, and advanced materials used in the construction of these devices.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not be limited to) the following:

  • Development of novel sensing layers,
  • Nanomaterials in sensors technology,
  • Novel sensors technology including miniaturization
  • Electrochemical sensors and biosensors for medical application, environmental monitoring, or the food industry.

We look forward to receiving your contributions.

Dr. Kamila Malecka-Baturo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sensor and biosensor technology
  • redox-active layers
  • signal amplification strategies
  • novel nanomaterials in sensor/biosensor design
  • miniaturization technologies in electrochemical sensor/biosensor design
  • electrochemical sensors and biosensors
  • medical diagnostics
  • environmental monitoring
  • food industry

Published Papers (4 papers)

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Editorial

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4 pages, 197 KiB  
Editorial
Advances in Electrochemical Sensors and Biosensors
by Kamila Malecka-Baturo
Coatings 2022, 12(8), 1052; https://doi.org/10.3390/coatings12081052 - 25 Jul 2022
Cited by 1 | Viewed by 1175
Abstract
The dynamic development of technology, consumer expectations, legal requirements, quality assurance and health safety systems create the need to develop new, highly selective and, at the same time, simple analytical tools [...] Full article
(This article belongs to the Special Issue Advances in Electrochemical Sensors and Biosensors)

Research

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14 pages, 3627 KiB  
Article
Polypyrrole/α-Fe2O3 Hybrids for Enhanced Electrochemical Sensing Performance towards Uric Acid
by Renjie Wang, Shanshan Liu, Xudong Song, Kai Jiang, Yaohui Hou, Qiaohuan Cheng, Wei Miao, Li Tian, Ying Ren and Sankui Xu
Coatings 2024, 14(2), 227; https://doi.org/10.3390/coatings14020227 - 15 Feb 2024
Viewed by 819
Abstract
Uric acid, a metabolite formed by the oxidation of purines in the human body, plays a crucial role in disease development when its metabolism is altered. Various techniques have been employed for uric acid analysis, with electrochemical sensing emerging as a sensitive, selective, [...] Read more.
Uric acid, a metabolite formed by the oxidation of purines in the human body, plays a crucial role in disease development when its metabolism is altered. Various techniques have been employed for uric acid analysis, with electrochemical sensing emerging as a sensitive, selective, affordable, rapid, and simple approach. In this study, we developed a polymer-based sensor (PPy/α-Fe2O3) for the accurate determination of uric acid levels. The PPy/α-Fe2O3 hybrids were synthesized using an uncomplicated in situ growth technique. Characterization of the samples was performed using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The electrochemical sensing performance towards uric acid was evaluated through cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The obtained results demonstrated that the sensor exhibited excellent sensitivity towards uric acid detection within a wide range of 5–200 μM with a limit of detection (LOD) as low as 1.349 μM. Furthermore, this work elucidated the underlying sensing mechanism and highlighted the pivotal role played by PPy/α-Fe2O3 hybrids in enabling efficient uric acid sensing applications using electrochemical sensors. Full article
(This article belongs to the Special Issue Advances in Electrochemical Sensors and Biosensors)
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13 pages, 2909 KiB  
Article
Human Teeth Disease Detection Using Refractive Index Based Surface Plasmon Resonance Biosensor
by Mohammad Khursheed Alam, Vigneswaran Dhasarathan, Ayyanar Natesan, Ramanujam Nambi, Mahmud Uz Zaman, Kiran Kumar Ganji, Rehana Basri, Manay Srinivas Munisekhar, Anil Kumar Nagarajappa and Huda Abutayyem
Coatings 2022, 12(10), 1398; https://doi.org/10.3390/coatings12101398 - 25 Sep 2022
Cited by 12 | Viewed by 3005
Abstract
The paper proposes a surface plasmon resonance (SPR) biosensor utilizing MXene and a Molybdenum Disulfide (MoS2) material layer, placed on the Ag metal-based conventional biosensor to detect disease in human teeth. The SPR biosensor works on the principle of attenuated total [...] Read more.
The paper proposes a surface plasmon resonance (SPR) biosensor utilizing MXene and a Molybdenum Disulfide (MoS2) material layer, placed on the Ag metal-based conventional biosensor to detect disease in human teeth. The SPR biosensor works on the principle of attenuated total reflection. The transverse matrix method was utilized for the reflectivity calculation. The thickness of the Ag layer, MXene, and MoS2 were taken as 45, 0.993, and 0.375 nm, respectively. Single-layer MoS2 and two layers of MXene were taken, and the highest sensitivity of the sensor for the enamel, dentin, and cementum was obtained at 83.219 deg/RIU, 91.460 deg/RIU, and 104.744 deg/RIU. MoS2 was used to enhance the biocompatibility of the analyte with the sensing layer. The aqueous solution had been considered as sensing medium. Full article
(This article belongs to the Special Issue Advances in Electrochemical Sensors and Biosensors)
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Review

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21 pages, 2083 KiB  
Review
An Overview of the Latest Developments in the Electrochemical Aptasensing of Neurodegenerative Diseases
by Edyta Mikuła and Kamila Malecka-Baturo
Coatings 2023, 13(2), 235; https://doi.org/10.3390/coatings13020235 - 19 Jan 2023
Viewed by 1650
Abstract
Neurodegenerative diseases (NDs) are becoming a major global health problem. They constitute an incurable diverse group of disorders characterized by the progressive degeneration of the structure and function of the central or peripheral nervous system. There is an enormous unmet demand worldwide for [...] Read more.
Neurodegenerative diseases (NDs) are becoming a major global health problem. They constitute an incurable diverse group of disorders characterized by the progressive degeneration of the structure and function of the central or peripheral nervous system. There is an enormous unmet demand worldwide for methods for the early detection of ND biomarkers. The complexity of the molecular mechanisms underlying neuronal degeneration as well as the inhomogeneity of the patient population pose a great challenge for the development of early diagnostic tools. Various analytical technologies have been developed to meet this challenge. Among the various approaches reported so far, biosensors are powerful analytical implements that have been applied to detect biomarkers of NDs. Over the past decade, electrochemical aptasensors have been at the forefront of this development not only thanks to their low cost and simple design but also due to advances in nanomaterials modifying the surface of the transducers involved. The design of electrochemical aptasensors for the detection of ND biomarkers such as α-synuclein, amyloid β peptide, tau protein and human cellular prion protein were summarized and compared. Innovative strategies for increasing their sensitivity and selectivity were also pointed out. Undoubtedly, there is still a need for low-cost, fast and easy-to-use systems for the early detection of NDs. Full article
(This article belongs to the Special Issue Advances in Electrochemical Sensors and Biosensors)
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