Coatings and Surface Modification of Biomaterials

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 2444

Special Issue Editor


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Guest Editor
Institute of Chemistry, Research Park of Saint Petersburg State University, 198504 Saint Petersburg, Russia
Interests: atomic layer deposition; thin films; coatings; surface science; biomaterials; medical implants, Li-ion batteries
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biomaterials are a special class of materials involving the combination of numerous functional properties. Depending on the field of application, certain mechanical characteristics, chemical and corrosion resistance, bioactivity or bioinertness, antibacterial properties, etc., may be required. These properties of biomaterials are determined by the specific composition, topography, charge, and structure of the surface. Despite the large number of studies on the surface modification of biomaterials, many problems remain unsolved. For example, the problem of combining antibacterial activity and high biocompatibility with living cells has not been fully resolved. The ability to precisely control the decomposition rate of biodegradable materials also requires further development. At the same time, to solve these and many other problems, a deeper and more detailed understanding of the processes occurring at the living cell–biomaterial interface is required. Hence, at present, defining the relationship between the surface characteristics and functional properties of biomaterials is one of the most important tasks of both fundamental and applied science.

This Special Issue aims to summarize novel research on the surface modification of biomaterials and the effect of new characteristics of biomaterials on their functional properties.
Particular topics of interest include but are not limited to

  • Biomaterials
  • Bioactivity
  • Dental materials
  • Orthopedic materials
  • Osseointegration
  • Surface engineering
  • Surface treatment
  • bioactive coatings
  • Protective coatings
  • Antibacterial coatings

Dr. Denis Nazarov
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

19 pages, 6958 KiB  
Article
MG-63 and FetMSC Cell Response on Atomic Layer Deposited TiO2 Nanolayers Prepared Using Titanium Tetrachloride and Tetraisopropoxide
by Denis Nazarov, Ilya Ezhov, Natalia Yudintceva, Ilya Mitrofanov, Maxim Shevtsov, Aida Rudakova and Maxim Maximov
Coatings 2022, 12(5), 668; https://doi.org/10.3390/coatings12050668 - 13 May 2022
Cited by 2 | Viewed by 2025
Abstract
Titanium oxide nanocoatings were synthesized on the surface of monocrystalline silicon and ultra-fine-grained titanium by atomic layer deposition (ALD) using titanium tetrachloride (TiCl4) and titanium tetraisopropoxide (TTIP). The morphology of the samples was studied by scanning electron microscopy (SEM) and transmission [...] Read more.
Titanium oxide nanocoatings were synthesized on the surface of monocrystalline silicon and ultra-fine-grained titanium by atomic layer deposition (ALD) using titanium tetrachloride (TiCl4) and titanium tetraisopropoxide (TTIP). The morphology of the samples was studied by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The structure and composition were studied by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), contact angle measurements, and energy-dispersive spectroscopy (EDS). The cytological response of osteosarcoma MG-63 and human fetal mesenchymal stem cells (FetMSCs) were studied by analyzing their morphology, viability, and alkaline phosphatase activity with and without the use of medium-induced differentiation in the osteogenic direction. A significant influence of the precursor type and ALD temperature on the crystal structure, morphology, composition, and surface free energy of TiO2 nanocoatings was found. The biocompatibility of amorphous non-stoichiometric and partially crystalline stoichiometric TiO2 coatings was compared. Both types of cells showed faster adhesion and improved spreading on the surface for the samples from TTIP compared to those from TiCl4 at the early stages of cultivation (2 h) due to the difference in composition and higher surface free energy. No cytotoxic effect was found on both types of coatings, nor was there a noticeable difference in cell differentiation. All ALD coatings provided excellent biocompatibility and osteoconductive properties. Full article
(This article belongs to the Special Issue Coatings and Surface Modification of Biomaterials)
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