Molecular Mechanism of HPV’s Involvement in Cancers
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 237
Special Issue Editor
Special Issue Information
Dear Colleagues,
Human papillomavirus (HPV) can cause cancer at multiple anatomical sites in both men and women. The expression of high-risk HPV types E6/E7 initiates a process of malignant transformation, including the evasion of cell cycle control, the inhibition of apoptosis, and the activation of proliferation-promoting gene transcription. HPV in vitro models and transgenic mouse models have been generated and characterized. These models provide a good platform for understanding the biological properties of HPV genes; however, further studies on the difference between molecular profiling and possible therapeutic targets between HPV-positive and HPV-negative cancers are needed to understand whether specific changes promote HPV-associated tumorigenesis.
We welcome research papers focusing on HPV or HPV-related cancers. Potential topics of interest include but are not limited to the following:
- The role of HPV in various cancers, including the molecular pathways of HPV-related cancers and experimental models for studying HPV-related cancers.
- How studying HPV-related pathways that lead to carcinogenesis will improve our understanding of HPV carcinogenesis.
- HPV genotyping, immune balance, and escape between HPV subtypes and other viruses, as well as immune intervention in HPV infection.
- Novel therapeutic molecular targets and its therapeutic effects for HPV-associated cancers.
Dr. Xuesong Wen
Guest Editor
Manuscript Submission Information
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Keywords
- HPV
- HPV carcinogenesis
- viral interaction
- HPV genotyping
- head and neck cancer
- immune balance
- cervical cancer
