Signaling Pathways of Breast Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 3018
Special Issue Editors
Interests: breast cancer; bone metastases; drug resistance; RANKL-RANK pathway
Special Issue Information
Dear Colleagues,
Breast cancer is the most common malignancy worldwide. Its heterogeneous etiology, histology and molecular profile are translated into distinct intrinsic sub-types, associated with different types of biology and prognoses.
Major breakthroughs in breast cancer treatment were fueled by targeted therapies, with the most striking being the endocrine and anti-HER2 therapies and, more recently, the CDK4/6 inhibitors. However, intrinsic and acquired resistance are almost inevitable.
By increasing our knowledge about the signaling pathways involved in major breast cancer hallmarks, about their crosstalk and target ability, and about their role in response to standard of care or new therapies, we may envisage an improvement in the prognosis of breast cancer patients.
This Special Issue of Cancers intends to gather new breakthrough research, focusing on the multiple aspects and relevance of signaling pathways in breast cancer.
Prof. Dr. Sandra Casimiro
Dr. Marta Martins
Guest Editors
Manuscript Submission Information
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Keywords
- Breast cancer
- signal transduction
- targeted therapies
- resistance to therapy
- novel molecular mechanisms