Oncogenetics of Colorectal Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Pathophysiology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 122
Special Issue Editors
2. Department of Public Health Sciences, Biological Sciences Division, University of Chicago, Chicago, IL 60637, USA
Interests: colorectal carcinoma; microsatellite instability; cytogenetics; molecular genomics; GWAS; copy number change; telomere; methylation; liquid biopsy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Colorectal carcinoma (CRC) is one of the most common cancers worldwide. It represents a heterogeneous group of disorders from a molecular genomic point of view. Sporadic CRC is the most common form and is associated with somatic mutations, DNA methylation, genomic instability in the form of copy number changes, and microsatellite instability. Inflammatory pathways and host immune response have been associated not only with pathogenesis but also targeted therapeutic options. Many of the changes occurring are also reflected in liquid biopsy samples. Full use of known and yet-to-be-known molecular changes in the tumor tissue and/or liquid biopsy for predictive, diagnostic, therapeutic, and prognostic purposes could improve personalized therapy.
This Special Issue aims to focus on original research papers and review articles on different molecular genomic and epigenetic changes in CRC tissue and liquid biopsy and their association with the pathogenesis of CRC as well as therapeutic applications and outcomes.
Dr. Muhammad Kibriya
Dr. Marc Bissonnette
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- colorectal carcinoma
- somatic mutation
- microsatellite instability
- methylation
- copy number change
- tumor-infiltrating leukocyte
- immune checkpoint inhibitor
- drug resistance
- cell-free DNA
