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Cancers
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Advancements in Surgical Approaches for Gynecological Cancers
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Advancements in Surgical Approaches for Gynecological Cancers

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 1 December 2024 | Viewed by 1684

Special Issue Editors

Dr. Anna Myriam Perrone

E-Mail Website
Guest Editor
Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
Interests: advancements in surgical techniques; surgical planning and decision-making; outcomes and challenges; patient-centered care
Special Issues, Collections and Topics in MDPI journals
Dr. Camelia Alexandra Coada

E-Mail Website
Guest Editor
Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
Interests: impact on long-term survival; multidisciplinary collaboration; current treatment challenges; molecular classification of tumors and their prognostic impact

Special Issue Information

Dear Colleagues,

Gynecological cancers, including ovarian, cervical, uterine, vulvar, and vaginal cancers, pose significant health challenges for women worldwide. With millions of women diagnosed each year, these cancers have a profound impact on both individual lives and public health. However, thanks to remarkable advancements in surgical approaches, there is newfound hope in the fight against gynecological cancers. Scientific breakthroughs and technological innovations have revolutionized the field of gynecologic oncology, offering safer, more precise, and minimally invasive surgical techniques. These advancements not only enhance diagnostic accuracy but also enable surgeons to tailor treatment plans and improve patient outcomes. The importance of these advancements in surgical approaches for gynecological cancers cannot be overstated, as they hold the potential to improve patient outcomes, enhance quality of life, and redefine the landscape of gynecologic oncology care.

We are pleased to invite you to contribute to this Special Issue titled “Advancements in Surgical Approaches for Gynecological Cancers” dedicated to the surgery of gynecological cancers, focusing on the advancements, challenges, and outcomes in this critical field.

It is well known that achieving complete surgical resection has paramount importance in the management of tumors, including gynecological cancers. The aim of this Special Issue is to provide a comprehensive overview of the evolving surgical techniques, novel approaches, and cutting-edge technologies that are revolutionizing the management of gynecological cancers. The articles included in this issue should emphasize the significance of thorough surgical planning, meticulous techniques, and multidisciplinary collaboration to ensure optimal cytoreduction and achieve negative surgical margins. By addressing the challenges and complexities associated with achieving complete surgery, this Special Issue aims to underscore the significance of this essential treatment modality in improving overall survival rates and disease-free intervals for patients with gynecological cancers. Through a comprehensive exploration of surgical advancements, techniques, and outcomes, this issue seeks to advance the knowledge and understanding of the integral role of complete surgery in the comprehensive management of gynecological malignancies.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

Impact of advancements in molecular and genetic classifications on therapeutic choices.

Evolving surgical techniques.

Role of neoadjuvant chemotherapy in surgical outcomes.

Minimally invasive surgical approaches.

Novel approaches.

Cutting-edge technologies.

Thorough surgical planning.

Meticulous techniques.

Application of current treatment guidelines.

Optimal cytoreduction and negative surgical margins.

Impact on overall survival and disease-free intervals.

We look forward to receiving your contributions.

Dr. Anna Myriam Perrone
Dr. Camelia Alexandra Coada
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gynecological cancers
  • minimally invasive surgery
  • advancements in oncological treatments
  • challenges
  • survival outcomes
  • complete surgical resection
  • management
  • cytoreduction
  • negative surgical margins

Published Papers (2 papers)

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Research

10 pages, 1415 KiB  
Article
Breast-Conserving Surgery Guided with Magnetic Seeds vs. Wires: A Single-Institution Experience
by Elisa Moreno-Palacios, Covadonga Martí, Laura Frías, Marcos Meléndez, Adolfo Loayza, María José Roca, Vicenta Córdoba, José María Oliver, Alicia Hernández and José Ignacio Sánchez-Méndez
Cancers 2024, 16(3), 566; https://doi.org/10.3390/cancers16030566 - 29 Jan 2024
Viewed by 560
Abstract
Purpose: The aim of this study is to describe our initial experience using magnetic seeds (Magseed®) to guide breast-conserving surgery in non-palpable breast lesions and compare the use of magnetic seed with wires to guide breast-conserving surgery in terms of clinical [...] Read more.
Purpose: The aim of this study is to describe our initial experience using magnetic seeds (Magseed®) to guide breast-conserving surgery in non-palpable breast lesions and compare the use of magnetic seed with wires to guide breast-conserving surgery in terms of clinical and pathological characteristics. Methods: We performed a retrospective study including all breast-conserving surgeries for non-palpable breast lesions under 16 mm from June 2018 to May 2021. We compared breast-conserving surgeries guided with magnetic seeds (Magseed®) to those guided with wires, analyzing tumor and patient characteristics, surgical time, and pathological results of the surgical specimens. Results: Data from 225 cases were collected, including 149 cases guided by magnetic seeds and 76 cases guided by wires. The breast lesion was localized in every case. Both cohorts were similar regarding clinical and pathological characteristics. We found significant statistical differences (p < 0.02) in terms of the median volume (cm3) of the excised specimen, which was lower (29.3%) in the magnetic seed group compared with the wire group (32.5 [20.5–60.0]/46.0 [20.3–118.7]). We did not find significant differences regarding surgical time (min) or the affected or close margins. Conclusion: In our experience, the use of magnetic seed (Magseed®) is a feasible option to guide breast-conserving surgery of non-palpable lesions and enabled us to resect less breast tissue. Full article
(This article belongs to the Special Issue Advancements in Surgical Approaches for Gynecological Cancers)
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12 pages, 443 KiB  
Article
Urinary, Gastrointestinal, and Sexual Dysfunctions after Chemotherapy, Radiotherapy, Radical Surgery or Multimodal Treatment in Women with Locally Advanced Cervical Cancer: A Multicenter Retrospective Study
by Mariano Catello Di Donna, Giuseppe Cucinella, Vincenzo Giallombardo, Giulio Sozzi, Nicolò Bizzarri, Giovanni Scambia, Basilio Pecorino, Paolo Scollo, Roberto Berretta, Vito Andrea Capozzi, Antonio Simone Laganà and Vito Chiantera
Cancers 2023, 15(24), 5734; https://doi.org/10.3390/cancers15245734 - 07 Dec 2023
Viewed by 909
Abstract
Background: Different strategies have been proposed for the treatment of locally advanced cervical cancer (LACC), with different impacts on patient’s quality of life (QoL). This study aimed to analyze urinary, bowel, and sexual dysfunctions in a series of LACC patients who underwent chemotherapy, [...] Read more.
Background: Different strategies have been proposed for the treatment of locally advanced cervical cancer (LACC), with different impacts on patient’s quality of life (QoL). This study aimed to analyze urinary, bowel, and sexual dysfunctions in a series of LACC patients who underwent chemotherapy, radiotherapy, radical surgery, or a combination of these treatments. Methods: Patients with LACC who underwent neoadjuvant radio–chemotherapy (NART/CT; n = 35), neoadjuvant chemotherapy (NACT; n = 17), exclusive radio–chemotherapy (ERT/CT; n = 28), or upfront surgery (UPS; n = 10) from November 2010 to September 2019 were identified from five oncological referral centers. A customized questionnaire was used for the valuation of urinary, gastrointestinal, and sexual dysfunctions. Results: A total of 90 patients were included. Increased urinary frequency (>8 times/day) was higher in ERT/CT compared with NACT/RT (57.1% vs. 28.6%; p = 0.02) and NACT (57.1% vs. 17.6%; p = 0.01). The use of sanitary pads for urinary leakage was higher in ERT/CT compared with NACT/RT (42.9% vs. 14.3%; p = 0.01) and NACT (42.9% vs. 11.8%; p = 0.03). The rate of reduced evacuations (<3 times a week) was less in UPS compared with NACT/RT (50% vs. 97.1%; p < 0.01), NACT (50% vs. 88.2, p < 0.01), and ERT/CT (50% vs. 96.4%; p < 0.01). A total of 52 women were not sexually active after therapy, and pain was the principal reason for the avoidance of sexual activity. Conclusions: The rate and severity of urinary, gastrointestinal, and sexual dysfunction were similar in the four groups of treatment. Nevertheless, ERT/CT was associated with worse sexual and urinary outcomes. Full article
(This article belongs to the Special Issue Advancements in Surgical Approaches for Gynecological Cancers)
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