Emerging Insights into Cell Death in Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 25 October 2024 | Viewed by 259
Special Issue Editor
Interests: programmed cell death; apoptosis; leukaemia; epigenetic; acetylation; sirtuins
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are thrilled to announce a Special Issue entitled "Emerging Insights into Cell Death in Cancer" that delves into the intricate relationship between cell death pathways and cancer, building upon the foundational understanding laid out in the previous Special Issue, "Deregulation of Cell Death in Cancer". The delicate balance between cell proliferation and elimination is central to the maintenance of biological homeostasis, and disruptions to this equilibrium can lead to various pathologies, including cancer.
One of the key hallmarks of cancer is the evasion of apoptosis, a highly orchestrated programmed cell death process characterized by distinct cellular events such as membrane disruption, DNA fragmentation, and cellular debris removal. Understanding the molecular mechanisms underlying regulated cell death (RCD) is crucial for unraveling the complexities of cancer initiation, progression, and metastasis.
Recent advancements have led to the identification and classification of different forms of RCD, shedding light on novel targets and pathways for therapeutic intervention. Given the limitations of conventional diagnostic methods for early-stage cancer detection and the observed treatment resistance associated with apoptotic pathway dysregulation, there is a pressing need to explore the modulation and restoration of RCD equilibrium as a promising avenue for anticancer therapy.
This Special Issue aims to showcase cutting-edge research elucidating the interplay between cancer and RCD, offering fresh insights into cellular mechanisms, drug discovery, and therapeutic strategies centered around apoptosis. By delving deeper into the role of RCD in carcinogenesis, this collection of articles seeks to advance our understanding and pave the way for more effective cancer treatments.
We invite researchers, academicians, and practitioners to contribute original research articles, reviews, and communications that advance our understanding of regulated cancer death and its role in cancer.
Dr. Vincenzo Carafa
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cell death
- cancer
- apoptosis
- programmed cell death (PCD)
- regulated cell death (RCD)
- therapeutic strategies
- molecular mechanisms
- drug discovery
- cellular pathways
- biomarkers
- immunotherapy
- targeted therapy
- cellular signaling
- apoptotic regulators
