Extracellular Matrix Proteins in Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".

Deadline for manuscript submissions: 15 November 2024 | Viewed by 86

Special Issue Editors


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Guest Editor
Laboratory of Histology-Embryology, School of Medicine, The University of Crete, 71003 Heraklion, Greece
Interests: matrix pathobiology; cancer; inflammation; oxidative stress; cytotoxicity; matrix pathobiology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Laboratory of Histology-Embryology, Medical School, University of Crete, 71003 Heraklion, Greece
Interests: histology; cytology; tumor microenvironment

Special Issue Information

Dear Colleagues,

The transformed extracellular matrix (ECM) constitutes the non-cellular component of a cancerous microenvironment, and its interactions with cellular components (tumor cells, normal tissue cells, blood vessels, stromal cells and cells of the immune system) modulate cell function and morphology, signaling transductions and subsequently tumor development. Protein ECM components include proteoglycans (extracellular, pericellular/basement membrane and cell surface PGs), fibrous proteins (collagens, elastin) and glycoproteins (laminin, fibronectin). ECM remodeling and changes in composition influence cell proliferation, motility, adhesion and invasion.

This Special Issue focuses on describing and updating the role of ECM proteins in different cancer-type microenvironments as well as defining ECM-associated molecular and structural mechanisms in tumor development.

Original research articles and review articles related to the topic are invited for this Special Issue.

We look forward to receiving your contributions.

Dr. Dragana Nikitovic
Dr. Aikaterini Berdiaki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • extracellular matrix
  • cancer
  • tumor microenvironment
  • ECM proteins
  • proteoglycans
  • glycoproteins
  • collagens
  • fibrous proteins
  • molecular mechanisms

Published Papers

This special issue is now open for submission.
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