Precision Medicine Approaches for Prostate Cancer Diagnosis, Treatment, and Management
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Causes, Screening and Diagnosis".
Deadline for manuscript submissions: 23 July 2024 | Viewed by 146
Special Issue Editors
Interests: image guidance in radiation oncology; functional and physiological imaging; stereotactic body radiation therapy
Special Issues, Collections and Topics in MDPI journals
2. Department of Urology, University of California, Los Angeles, CA 90095, USA
Interests: radiation therapy; prostate cancer treatment; MR guided radiotherapy; clinical outcomes research
Special Issues, Collections and Topics in MDPI journals
Interests: image guided radiotherapy; deformable image registration; motion management; image quality improvement
Special Issue Information
Dear Colleagues,
Significant advancements in radiation therapy techniques for the treatment of prostate cancer have been made with a view to improving cancer control while minimizing side effects and enhancing patient convenience. In the past decade or so, the field has witnessed major advancements in the precision of radiation delivery, both in terms of physical precision, which aims to accurately deliver radiation to targets while minimizing the dose to surrounding healthy organs, and for biological precision, which tailors the treatment plan to each patient’s unique tumor biology and modifies the plan based on treatment response. One key radiation modality in the precision medicine approaches for prostate cancer is Stereotactic Body Radiation Therapy (SBRT), which has demonstrated non-inferior oncologic outcomes for intact prostate cancers compared to conventional radiotherapy, and has a comparable safety and toxicity profile. Furthermore, the development of advanced diagnostic imaging techniques, including multiparametric MRI and prostate-specific membrane antigen (PSMA PET/CT), has greatly improved the diagnosis and staging of prostate cancer and aided in precise radiation treatment planning by identifying high-risk areas within or outside the prostate. The use of advanced imaging guidance techniques during radiation delivery, such as onboard MRI on MR-linacs and Cone Beam CT (CBCT) combined with intra-fractional kV tracking on conventional linacs, has also improved radiation delivery precision, which therefore allows for smaller target margin expansions in order to further reduce radiation exposure to nearby healthy tissues. Adaptive radiotherapy is another noteworthy advancement, involving modifying the treatment plan throughout the course of therapy based on changes in the size, shape, or biology of the tumor or nearby organs before each delivered fraction. By adapting the treatment to the evolving characteristics of the tumor, adaptive radiotherapy enables the personalized and precise delivery of radiation therapy.
This Special Issue will showcase cutting-edge research in these areas of rapid advancement in radiation treatment for prostate cancer, and also provide perspectives for future development.
Dr. Minsong Cao
Dr. Amar U. Kishan
Dr. Yi Rong
Dr. Martin T. Ma
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- prostate
- radiation oncology
- stereotactic body radiation therapy (SBRT)
- image-guided radiation therapy (IGRT)
- prostate-specific membrane antigen (PSMA)
- adaptive radiotherapy
