Natural Products Targeting Mitochondria
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 2771
Special Issue Editor
Interests: mitochondrial bioenergetics; mitochondrial dynamics; aging; reactive oxygen/nitrogen species metabolism; oncometabolism; resveratrol
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Beyond their role as ATP-generating ‘powerhouses’, mitochondria are central to the life of the cell at many levels, including their contribution to biosynthetic pathways, their participation in reactive oxygen metabolism, and their pivotal role in apoptosis. Mitochondria are involved in the processes regulating cell proliferation, replicative senescence, and differentiation. Mitochondrial dysfunction, either due to inheritance or sporadic causes, is an important component of the etiologies of many common diseases, from neurodegeneration to cancer, to metabolic syndrome. The maintenance of mitochondrial form and function is thus an important foundational element of human health. Over the past several decades, much has been learned about the proteins and pathways involved in making mitochondria, distributing them within the cell (and even between cells), regulating their dynamic interactions with each other and the endoplasmic reticulum, and ultimately removing faulty mitochondria via degradation processes. These proteins and pathways are all potential molecular targets for manipulating mitochondria. In this Special Issue, we focus specifically on natural products—those that are produced by, and can be isolated from, plants, microbes, and animals—that interact with mitochondria directly or via effects on gene expression.
We invite review articles that provide expert summaries of how specific natural products interact with mitochondria. We also invite original papers describing the discovery of new natural products targeting mitochondria or provide increased molecular detail regarding the mechanisms by which established natural products affect mitochondria. Finally, new tools and/or methodologies that increase our ability to measure mitochondrial function/dysfunction in this context are also very much welcomed. This is an exciting time in mitochondrial biology and in the discovery and characterization of new natural products, and we believe this will be reflected in this Special Issue.
Dr. Jeffrey Stuart
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bioenergetics
- mitochondrial dynamics
- reactive oxygen species
- metabolism
- apoptosis
- natural product
- phytoestrogen
- live cell imaging
