Biomaterials and Technology for Tumor Engineering

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 147

Special Issue Editors

E-Mail Website
Guest Editor
Medical Laboratory Sciences and Public Health Department, Tarleton State University, Fort Worth, TX 76104, USA
Interests: 3D tumor models; cancer cell signatures; anticancer drug delivery systems; hydrogels; 3D bioprinting systems
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Co-Guest Editor
Department of Chemical, Biological and Bioengineering, North Carolina Agricultural and Technical State University, Greensboro, NC, USA
Interests: drug delivery; liver metabolism; cancer cell targeting; wound healing; cell spheroids; 3D co-culture; nanofiber scaffolds; electrospinning; bioprinting

Special Issue Information

Dear Colleagues,

Spheroids, tumoroids, and cell-laden 3D scaffolding systems are commonly used as 3D tumor engineering models for the study of various tumorigeneses. Different biomaterials that could mimic the natural microenvironment with or without blended forms have significantly advanced tumor engineering. A complex in vitro heterogeneous tumor, which is representative of biologically relevant tumors, is not only necessary for tumor studies, for example, in proliferation, growth, and cell signatures, but is also equally important in discovering the efficacies of anticancer drugs. The implantation of 3D tumors into an animal is a common practice for generating xenograft tumors. However, we cannot precisely monitor the growth of the tumor, because of physiological, metabolic, and cell-signature complexities in animal tissue. In addition, we do not have a complete set of physiological systems that resemble the in vivo tissue environment yet; therefore, we rely on the outcomes of animal studies. Biomaterials which could provide a native-like microenvironment to the cells and which facilitate the monitoring of cell migration, proliferation, and kinetic development of the tumors are in demand in tumor-model engineering. In addition, this Special Issue will consider the application of imaging systems which could support the tracing of tumor development in animal tissues.

The topics of interest of this Special Issue therefore include, but are not limited to:

  • Advancements in 3D tumor model engineering;
  • Advancements in in vivo tumor imaging systems;
  • Advancements in biomaterials;
  • Advancements in tumor spheroids;
  • Advancements in tumoroids;

Advancements in new protocols for blended biomaterials that could mimic native microenvironments.

Dr. Girdhari Rijal
Prof. Dr. Narayan Bhattarai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • three-dimensional tumor models
  • xenograft tumors
  • cancer cell signatures
  • H-scan ultrasound
  • in vivo imaging systems
  • dye-tagged cell technologies
  • scaffolds
  • tumoroids
  • spheroids
  • anticancer drugs

Published Papers

This special issue is now open for submission.
Back to TopTop