Recent Advance in Biomaterials for Bone Tissue Regeneration

Dear Colleagues,

Biomaterials are being developed in terms of surface modifications, composite materials, advanced surgical allografts and bone graft substitutes so that they can be used in bone tissue regeneration. Many studies have uncovered the mechanisms behind augmented bone healing, thereby promoting the collective understanding of arthrodesis and bone apposition. The traditional metals used in implantable medical devices for bone healing, either as an internal fixator or a part of an implant, are now processed with new additive manufacturing techniques. Thus, these internal fixators, complemented with the use of biomaterials, can now be found with modified surfaces that alter the cellular response. Recently, use of polymers that incorporate textured metal surfaces has also been suggested to increase the bone implant interface strength. Such modifications include a macroscopic scale feature to prevent expulsion and migration and microscale changes that facilitate bone ongrowth. These novel bone growth substitutes form a new category of synthetic bone healing materials, such as bioglass or calcium phosphates.

New processing techniques with additive manufacturing create an opportunity to produce a tailored bone implant interface while maintaining the structural properties found in hardware such as plates and screws. The role of the substrate as an osteoconductive surface has also been dramatically enhanced with the development of biomaterials. Furthermore, osteobiologics, used as surgical allografts, have also benefitted from advancements in the processing techniques.

To highlights these emerging research areas of bone healing, this Special Issue invites submissions of manuscripts dedicated to the use of biomaterials in bone tissue regeneration.

Prof. Dr. Boyle Cheng
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.