Computational Modeling of Additively Manufactured Artificial Bone for Replacement and Scaffolding in Orthopedics

Dear Colleagues,

This Special Issue aims to exhibit the latest studies on the computational modeling and mechanical testing of innovative additively manufactured 3D printed materials for bone tissue engineering.

Computational models that focus on the analyses of cellular 3D artificial bone tissue are of great interest to this Special Issue since critical-sized bone defects represent a significant challenge in the orthopedic field. The limitations of autograft and allograft as treatment techniques have led researchers to explore the implantation of artificial bone tissue scaffolds. Of interest, therefore, are studies related to bone scaffolds as a three-dimensional cellular structure that provides mechanical support and behave like a template for bone tissue formation. Similarly, studies that utilize finite element analysis (FEA) to perform optimized scaffold designs and explore the failure mechanisms of scaffold designs are also welcome, as are imaging studies using scanning electron microscopy (SEM) to characterize the structural configuration of the manufactured scaffolds. FEA that validate optimized, designed, and manufactured bone scaffolds using additive manufacturing with mechanical properties that relate to the cortical bone as part of bone tissue engineeringand studies that investigate the biocompatibility of the designed scaffolds and the host, are encouraged.

Modeling and analysis manuscripts dealing with cellular metal structures used as bone replacement segments in allograft application, are welcome. This Special issue has a strong interest in studies that develop materials mimicking the mechanics and the anatomy of real bone segments. Also welcome are studies that highlight proof of bone growth on a pre-determined scaffolding anatomy that represents bone segments from the femur, tibia, arm or any skeletal site. Also of interest are studies that focus on bone scaffolds that can be used for bone healing of crushed or non-healing fractures, for the anatomical correction of bone defects, for non-union fractures, and for the lengthening of limbs. Finally, this Special Issue welcomes research manuscripts covering spine bone and head injuries, hosting cartilage growth in deformed and collapsed spine discs, and the treatment of bone allograft for cancer related tumors.

• Potential topics include, but are not limited to, the following:
• Finite element modeling of bone structures and materials;
• Development of functional 3D scaffolds within tissue engineering;
• Structures bi-mimicking bone tissue;
• Advanced technologies for functional 3D scaffold engineering;
• New trends in additively manufactured bone structures;
• Testing and the mechanical properties of 3D manufactured bone structures;
• Computational models of cellular metallic bone tissue.

Dr. Adeeb Rahman
Guest Editor

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• functional scaffolds
• computational modeling of bone tissue
• bone implant interface
• 3D additively manufactured bone tissue
• bone segment replacement
• artificial bone material
• mechanical properties of artificial bone
• bone scaffolding
• 3D-printed scaffolds
• finite element modeling of bone structure
• bio-mimics of bone structure