Neonatal Cerebral Sinovenous Thrombosis and the Main Perinatal Risk Factors—A Retrospective Unicentric Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Clinical Characteristics | Mean ± Standard Deviation | Range | 95% Confidence Interval |
---|---|---|---|
Gestational age, weeks | 39.1 ± 1.26 | 37–41 | 38.13–40.08 |
Birth weight, g | 3493.3 ± 645.9 | 2700–4700 | 2996.78–3989.88 |
Apgar score, 1 min | 4.2 ± 2.4 | 1–7 | 2.34–6.09 |
Apgar score, 5 min | 6 ± 2.3 | 2–8 | 4.19–7.80 |
Length, cm | 50.8 ± 2 | 48–54 | 49.33–52.44 |
Head circumference, cm | 35.3 ± 1 | 34–37 | 34.56–36.10 |
Risk Factor | N (%) |
---|---|
Sex | Male = 5 (55.56%) Female = 4 (44.44%) |
Maternal thrombophilia | 7 (77.78%) |
Type of birth | Vaginal = 6 (66.67%) Cesarean = 3 (33.33%) |
Meconium aspiration | 4 (44.44%) |
Small for gestational age | 2 (22.22%) |
Perinatal asphyxia | 4 (44.44%) |
Shoulder dystocia | 1 (11.11%) |
Nuchal chord | 2 (22.22%) |
Mechanical ventilation | 8 (88.89%) |
Respiratory distress | 4 (44.44%) |
Clinical Manifestations | N (%) |
---|---|
Lethargy | 7 (77.78%) |
Feeding difficulties | 8 (88.89%) |
Seizures | 3 (33.33%) |
Bilateral inferior limb spasticity | 1 (11.11%) |
Respiratory failure | 4 (44.44%) |
Loss of consciousness | 3 (33.33%) |
Type of CSVT | N (%) |
---|---|
Number of sinuses involved | Single sinus = 5 (55.56%) Multiple sinuses = 4 (44.44%) |
Superior sagittal sinus | 7 (77.78%) |
Transverse sinus | 4 (44.44%) |
Sigmoid sinus | 2 (22.22%) |
Cavernous sinus | 1 (11.11%) |
Associated lesions | Diffuse cerebral edema = 3 (33.33%) Intraventricular hemorrhage = 2 (22.22%) Thalamic hemorrhage = 1 (11.11%) Choroid plexus hemorrhage = 1 (11.11%) Ventriculomegaly = 1 (11.11%) |
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Filip, C.; Zonda, G.I.; Vasilache, I.-A.; Scripcariu, I.S.; Vicoveanu, P.; Dima, V.; Socolov, D.; Paduraru, L. Neonatal Cerebral Sinovenous Thrombosis and the Main Perinatal Risk Factors—A Retrospective Unicentric Study. Children 2022, 9, 1182. https://doi.org/10.3390/children9081182
Filip C, Zonda GI, Vasilache I-A, Scripcariu IS, Vicoveanu P, Dima V, Socolov D, Paduraru L. Neonatal Cerebral Sinovenous Thrombosis and the Main Perinatal Risk Factors—A Retrospective Unicentric Study. Children. 2022; 9(8):1182. https://doi.org/10.3390/children9081182
Chicago/Turabian StyleFilip, Catalina, Gabriela Ildiko Zonda, Ingrid-Andrada Vasilache, Ioana Sadiye Scripcariu, Petronela Vicoveanu, Vlad Dima, Demetra Socolov, and Luminita Paduraru. 2022. "Neonatal Cerebral Sinovenous Thrombosis and the Main Perinatal Risk Factors—A Retrospective Unicentric Study" Children 9, no. 8: 1182. https://doi.org/10.3390/children9081182