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Review
Peer-Review Record

Pathogenesis of Paradoxical Reactions Associated with Targeted Biologic Agents for Inflammatory Skin Diseases

Biomedicines 2022, 10(7), 1485; https://doi.org/10.3390/biomedicines10071485
by Fumi Miyagawa
Reviewer 1:
Reviewer 2:
Biomedicines 2022, 10(7), 1485; https://doi.org/10.3390/biomedicines10071485
Submission received: 25 May 2022 / Revised: 16 June 2022 / Accepted: 21 June 2022 / Published: 23 June 2022
(This article belongs to the Special Issue Pathogenesis and Treatment of Autoimmune and Inflammatory Diseases)

Round 1

Reviewer 1 Report

Is the histologic pattern of PRs similar or equal to the principal diseases? Do the eosinophils appear in the great amount? How long do the side effects last after the witdrawl of pathogenetic agents? Do you know some predisposing factors?

 

 

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

The review paper is comprehensive and concise. All of the considerable points in the topic are included. The authors managed to gather the data existing on the paradoxical reactions caused by biologic therapy for inflammatory skin diseases and to establish valid conclusions.

No major flaws are associated with this paper.

Minor points:

1. If possible, add illustrative material for the second part of the review

 

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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