Differences in the Pro/Antioxidative Status and Cellular Stress Response in Elderly Women after 6 Weeks of Exercise Training Supported by 1000 mg of Vitamin C Supplementation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Diet Analysis
2.3. Training
2.4. Supplementation
2.5. Determination of Maximum Oxygen Uptake
2.6. RNA Isolation
2.7. Reverse Transcription and qRT-PCR
2.8. Assessment of Plasma Vitamin C Level
2.9. Biochemical Analysis
2.10. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Parameter | SUPP Group (n = 18) | dCohen | CON Group (n = 18) | dCohen | 2-Way ANOVA | ||||
---|---|---|---|---|---|---|---|---|---|
Baseline (x ± SD) | After (x ± SD) | Change (x ± SD) | Baseline (x ± SD) | After (x ± SD) | Change (x ± SD) | ||||
Body mass (kg) | 71.1 ± 9.0 | 70.4 ± 10.4 | −0.7 ± 2.9 | 0.02 | 71.3 ± 0.4 | 68.8 * ± 10.5 | −2.4 ± 3.9 | 0.15 | # row factor (p < 0.0001) |
VO2 max. (mL/kg/min) | 20.6.± 3.6 | 21.4 ± 3.9 | 0.9 ± 1.4 | 0.19 | 21.3 ± 3.8 | 21.4 ± 3.8 | 0.1 ± 0.75 | 0.00 | # interaction (p = 0.0006) # row factor (p < 0.0001) |
Vit. C concent. (μmol/L) | 14.0 ± 3.9 | 18.0 * ± 7.8 | 3.9 ± 6.4 ↑ * | 0.44 | 14.5 ± 7.1 | 14.7 ± 3.9 | 0.2 ± 5.7 | 0.08 | # row factor (p < 0.0001) |
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Żychowska, M.; Sadowska-Krępa, E.; Damiani, E.; Tiano, L.; Ziemann, E.; Nowak-Zaleska, A.; Lipińska, P.; Piotrowska, A.; Czerwińska-Ledwig, O.; Pilch, W.; et al. Differences in the Pro/Antioxidative Status and Cellular Stress Response in Elderly Women after 6 Weeks of Exercise Training Supported by 1000 mg of Vitamin C Supplementation. Biomedicines 2022, 10, 2641. https://doi.org/10.3390/biomedicines10102641
Żychowska M, Sadowska-Krępa E, Damiani E, Tiano L, Ziemann E, Nowak-Zaleska A, Lipińska P, Piotrowska A, Czerwińska-Ledwig O, Pilch W, et al. Differences in the Pro/Antioxidative Status and Cellular Stress Response in Elderly Women after 6 Weeks of Exercise Training Supported by 1000 mg of Vitamin C Supplementation. Biomedicines. 2022; 10(10):2641. https://doi.org/10.3390/biomedicines10102641
Chicago/Turabian StyleŻychowska, Małgorzata, Ewa Sadowska-Krępa, Elisabetta Damiani, Luca Tiano, Ewa Ziemann, Alicja Nowak-Zaleska, Patrycja Lipińska, Anna Piotrowska, Olga Czerwińska-Ledwig, Wanda Pilch, and et al. 2022. "Differences in the Pro/Antioxidative Status and Cellular Stress Response in Elderly Women after 6 Weeks of Exercise Training Supported by 1000 mg of Vitamin C Supplementation" Biomedicines 10, no. 10: 2641. https://doi.org/10.3390/biomedicines10102641