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Background:
Systematic Review

Clinically Preferred Videolaryngoscopes in Airway Management: An Updated Systematic Review

by
Vikram Nedunchezhian
1,
Ishvar Nedunchezhian
2 and
André Van Zundert
1,*
1
Department of Anaesthesia and Perioperative Medicine, Royal Brisbane and Women’s Hospital, The University of Queensland, Brisbane, QLD 4029, Australia
2
School of Medicine and Dentistry, Griffith University, Gold Coast, QLD 4215, Australia
*
Author to whom correspondence should be addressed.
Healthcare 2023, 11(17), 2383; https://doi.org/10.3390/healthcare11172383
Submission received: 29 June 2023 / Revised: 11 August 2023 / Accepted: 21 August 2023 / Published: 24 August 2023
(This article belongs to the Special Issue New Developments in Endotracheal Intubation and Airway Management)

Abstract

:
Videolaryngoscopes (VLs) have emerged as a safety net offering several advantages over direct laryngoscopy (DL). The aim of this study is to expand on our previous study conducted in 2016, to deduce which VL is most preferred by clinicians and to highlight any changes that may have occurred over the past 7 years. An extensive systematic literature review was performed on Medline, Embase, Web of Science, and Cochrane Central Database of Controlled Studies for articles published between September 2016 and January 2023. This review highlighted similar results to our study in 2016, with the CMAC being the most preferred for non-channelled laryngoscopes, closely followed by the GlideScope. For channelled videolaryngoscopes, the Pentax AWS was the most clinically preferred. This review also highlighted that there are minimal studies that compare the most-used VLs, and thus we suggest that future studies directly compare the most-used and -preferred VLs as well as the specific nature of blades to attain more useful results.

1. Introduction

Airway management is one of the most critical tasks an anaesthetist will encounter in their practice. Facing an unanticipated difficult airway is a complex and stressful task for any anaesthetist and requires great skill to overcome [1]. The primary goal of Endotracheal Intubation (ETI) is to establish a patent and safe airway whilst avoiding complications such as dental injuries or trauma to the anatomy surrounding the trachea. Over the years, there has been an evolution in the shape, size and material of laryngoscopes to optimise the effectiveness and, therefore, the safety of ETI [2]. Currently, direct laryngoscopy (DL) is standard practice for ETI, despite not always yielding a positive outcome [3]. A negative outcome can be referred to as a ‘can’t intubate, can’t ventilate” scenario, potentially requiring front-of-neck access, possibly leading to complications such as hypoxia and neurological injury [4]. Although significant advancements in DL have taken place over the past few decades, predicting a difficult airway remains a challenging task for anaesthetists.
Despite extensive pre-anaesthetic assessments and precautions being undertaken, no single parameter can accurately predict an unanticipated difficult airway [5]. Hence, it is vital that clinicians are always prepared to encounter an unanticipated difficult airway, with the literature suggesting that approximately 90% of difficult intubations are unanticipated by clinicians [6].
Therefore, in problematic situations, a safety net for anaesthesiologists is essential to provide the utmost care for the patient. Contemporarily, videolaryngoscopes (VLs) have provided a safeguard for anaesthetists due to the advantages they provide over DLs. Videolaryngoscopy (VL) is a modern technique that uses a camera and a light source mounted on a laryngoscope blade to enable a magnified and improved view of the larynx and glottis on a screen. With a growing body of evidence and significant technological advances, VLs have recently proven to be a popular choice of device for ETI by clinicians. A meta-analysis published in 2021 concluded that there are several advantages highlighted in using a VL over a DL [3]:
  • Higher first-pass success: VLs increased the chance of first-pass success (successful intubation on first attempt) when compared to DLs.
  • Fewer failed intubations: VLs resulted in fewer failed intubations when compared to DLs, even in anticipated difficult airways.
  • Fewer hypoxemic events: VLs showed a reduction in hypoxemic events when compared to DLs.
  • Increased glottic views: certain VLs provided an improved visualisation of the glottis in accordance with the Cormack–Lehane grade, which can reduce the likelihood of adverse events such as failed intubation or airway trauma.
  • Less sore throat: there was a lower incidence of patient-reported sore throat post-intubation using VLs, hence possibly reducing patient anxiety with intubation.
With an increase in VL use over the past decade, it is important to juxtapose the safety and efficacy of the different types of VLs. The ideal VL should deliver a high chance of first-pass successful intubation with good glottic views in a short amount of time and be readily available and cost-effective. Our previous study published in 2016 identified that the most clinically preferred VLs were the Pentax-AWS VL for channelled VLs and the Karl Storz C-MAC for non-channelled VLs [7].
The aim of this paper is to expand on our previous study to establish which VL is most preferred by clinicians, to further aid decision-making for safer and more effective ETI, and to ascertain whether any changes have occurred over the past 7 years in clinician preference.

2. Materials and Methods

Eligibility and Search Strategy: An extensive systematic literature review was performed on Medline, Embase, Web of Science, and Cochrane Central Database of Controlled Studies for articles published between September 2016 and January 2023. The search terms included, but were not limited to: laryngoscope, laryngoscop*, videolaryngoscope, video-laryngoscope, “video laryngoscope”, videolaryngoscop*, video-laryngoscop*, “video laryngoscop*”, glidescope, macintosh, cmac, mcgrath, airtaq, “king vision”, “pentax aws”. Results were further refined to cohort studies and randomised controlled trials. A manual review of references was also performed to ensure an elaborate search. We restricted our search to English-only articles. A PRISMA checklist was used to ensure an optimal strategy, with a summary provided in Figure 1. This study was registered in PROSPERO.
Study Selection and Data Extraction: We included studies that compared either of the following between two or more videolaryngoscopes: (a) improved glottis view (either Cormack–Lehane grade or percentage of glottic opening); (b) time to successful intubation; (c) first-pass intubation success rate; (d) use of corrective manoeuvres or adjuncts; e) final outcomes judged by authors as “preferred” and/or “best” VL. Based on the factors ‘a–e’, we determined which VL was clinically preferred for each study. Data were manually extracted and cross-reviewed by the authors to optimise interrater reliability. These data were further collated to evaluate the favoured percentage of each VL. The studies chosen were grouped into either clinical patient studies or simulation studies. Table 1 demonstrates the VLs identified through our comprehensive study selection and data extraction phase.

3. Results

Our search yielded 3841 studies (Medline—794 results, Embase—792 results, Cochrane Library—1543 results, Web of Science—712 results). After the removal of duplicates, studies that had undergone erratum, trials registered but not yet published and meeting abstracts not yet published, 1405 articles remained. Publications that contained unrelated context or did not meet the inclusion criteria were excluded from this study.
This review included 81 studies with a total of 50 surgical studies conducted on 6274 patients, and 31 simulation studies conducted with 1353 participants. Table 2 highlights the key elements of each surgical study, while Table 3 highlights the key elements of the simulation studies. Importantly, we identified the clinically preferred VL and blade type in each of these study groups, as demonstrated in the respective tables.
In studies evaluating surgical patients, the CMAC was the most-used VL, with 25 out of 50 studies investigating it, closely followed by the McGrath VL (19 out of 50 studies). Of note, in surgical patients, the CMAC Macintosh blade was used 14 times, the CMAC angulated D blade was used 8 times, and the CMAC Miller blade was used 3 times. In the studies that investigated the McGrath VL, 13 used the Macintosh-style blade and 6 used the angulated blade. For studies evaluating manikins, the GlideScope was the most commonly used VL, with 14 out of 31 studies investigating it, all of which used an acute-angulated blade.
Table 4 summarises the review, with less commonly used VLs excluded. The CMAC was found to be the most-preferred non-channelled VL overall (preferred in 70% of studies that investigated CMAC), closely followed by the GlideScope (preferred in 67% of studies that investigated GlideScope). It is interesting to note that the most frequently used non-channelled VLs all scored > 50% preference in surgical studies, yet only the CMAC and GlideScope scored > 50% in simulation studies.
For channelled laryngoscopes, the AWS was the most-preferred overall, with 69% of studies that evaluated this VL preferring it; however, only 50% of surgical studies preferred this VL.
When analysing the data, it was established that the most-used VLs were not often directly compared. Out of the 50 studies reviewing clinical scenarios, the CMAC and GlideScope were only directly compared three times, and when reviewing simulation studies, they were only compared two times. Out of the clinical studies, the CMAC was preferred in two out of the three studies, whilst in the simulation studies the CMAC was preferred in one study, and the other found the CMAC and GlideScope to be similar. When comparing the CMAC to Pentax AWS, no clinical study directly compared the two VLs, and the one simulation study that compared them showed a preference for the Pentax AWS. Figure 2 demonstrates the most commonly preferred VLs.

4. Discussion

This review aimed to establish which VL is most clinically preferred, with the goal of expanding on our previous review published in 2016. Similar to previously, the Pentax AWS was the most preferred overall for channelled VLs, and the CMAC was the most preferred overall for non-channelled VLs.
However, our review discovered that the more recent literature suggests that other VLs are also gaining popularity among clinicians. For instance, our previous review suggested that the GlideScope acute-angled blade was preferred in only 41% of clinical studies and 7% of simulation studies, whereas our updated review highlights that it was preferred in 69% of clinical studies and 64% of simulation studies. Likewise, the efficacy of the McGrath VL appears to have increased drastically from the previous review, increasing from a preference rate of 25% to 63% in clinical studies, and 17% to 44% in simulation studies. We hypothesise that this increase is due to the ever-expanding use, availability and familiarity with VLs. Further to this, McGrath Blades have released Macintosh-style blades, which clinicians have historically been more familiar with. With regards to our study, it is noted that a McGrath Macintosh-style blade was used in 13 of 19 clinical studies and 7 of 9 simulation studies. Again, this change may be a reason for the growing popularity and preference for the McGrath VL. Similarly, GlideScope has also released Macintosh-style blades; however, the studies in this review all appear to use the acute-angle blade. Ultimately, clinicians are more likely to perform better with and prefer a VL that they are familiar with and use more often.
The literature suggests that acute-angle blades should be reserved for predicted or known difficult airway situations, especially in patients with an anterior larynx [89]. Thus, the use of acute-angle VLs may be detrimental, in comparison to standard Macintosh-style blades, for the intubation of normal airways. One such reason is that acute-angle VLs only provide an indirect view and present with a sharp angle, resulting in the ETT needing to be introduced with a device such as a stylet to ensure it is able to be manipulated around the steep angle [89]. Thus, one limitation of the papers studied in this review is the comparison of acute-angle blades to Macintosh-style blades, as the clinical indication for each is different.
In addition to this, there were a minimal number of studies that directly compared the most-preferred VLs. For instance, the two most-preferred non-channelled VLs, the CMAC and GlideScope, were only directly compared three times in clinical studies and two times in simulation studies. Similarly, when attempting to discuss the CMAC and Pentax AWS, no clinical study directly compared these two VLs and only one simulation study directly compared them. This limits the generalisability of the current literature, as a direct comparison and evaluation of the most-preferred VLs are not able to be conducted based on the current literature. One potential reason hypothesised is the cost involved with comparing the more expensive and most-preferred VLs. Further to this, the financial implications of acquiring, using, and maintaining VLs may limit certain departments’ ability to use VLs, and we suggest they check what is available and suitable for their needs. We also propose that the current literature favours the most commonly used VLs, and true clinician preference would be better ascertained in future studies evaluating more head-to-head comparisons and thus, more direct parameters for clinician preference.
Furthermore, as discussed in our previous review, it must be acknowledged that clinical studies conducted on patients will differ rather significantly compared to simulation studies performed on manikins. This is highlighted in the stark difference in the performance of some VLs in clinical studies versus simulation studies. If we base our results purely on clinical studies, it would highlight that the King Vision non-channelled and Airtraq VLs may be the most suitable to use. However, both these VLs performed quite poorly in manikin models and had a <35% preference in their respective studies. Furthermore, with a minimal direct comparison between these VLs and the aforementioned most-preferred VLs, this would not be generalisable. The CMAC, GlideScope and Pentax AWS were the only VLs preferred in ≥50% of both clinical and simulation studies.
For future use and teaching prospects, it is important to recognise extra components that may render particular VLs more preferable. For instance, the Macintosh-style blades used in the CMAC VLs can be used as both a direct and indirect laryngoscope as the video monitor is mounted separately to the laryngoscope. Therefore, in a scenario where a clinician wants to teach with this VL, the trainee can use a direct view for education, whilst the teacher can observe through the monitor to ensure the adequate placement of the endotracheal tube. Similarly, if a difficulty is encountered, a supervisor can take over, or the anaesthesia assistant can anticipate what to do next, such as preparing a bougie. Anecdotally, this method of laryngoscopy ensures safer management and education. Similarly, the McGrath VL can serve the same teaching process; however, a key difference is that the monitor is attached to the top of the VL itself, rather than mounted separately. Furthermore, different manufacturers offer different specifications in their VLs. Some provide the option for multiple types of blades or attachments such as fibreoptic scopes to be used with one VL handle, others offer longer battery life, whereas some offer the option for single-use vs reusable blades. These additional features make particular VLs more appealing, depending on the clinicians’ preferences and requirements.
A limitation to this article is that VLs were purely chosen based on their functionality in intubating a patient or manikin, without considering the resources/equipment used. For future studies, it is important to compare the cost burden for hospitals alongside clinician preference to ensure a more complete approach towards selecting the most ideal VL. Studies in the future should also be more transparent with the specific details of the VLs being used, including the type of blade, size, reusability, and/or single-use nature of the VLs. We also advocate for future studies to more thoroughly identify patient and institutional factors that may lead to the use of, or preference for, a particular VL, with the aim to provide transparency to readers regarding scenarios where particular VLs may be more favourable.
Furthermore, as aforementioned, a limitation in the current literature is the lack of comparison between the most-used and -preferred laryngoscopes. In addition to this, studies in the future should compare VLs with Macintosh-style blades to other VLs with Macintosh-style blades, and likewise acute-angle blades with acute-angle blades. This will allow for more streamlined and consistent results. Essentially, we advocate for standardisation criteria to ensure the appropriate comparison of devices. The studies reviewed also did not consistently describe the experience level of the operators performing intubation, and suggestions for future studies would be to highlight this to ensure transparency, as it is well-known that clinicians will prefer and perform better with equipment that they are more familiar with. To achieve optimal clinical outcomes, we advocate that clinicians choose the VL that they are most comfortable with depending on the clinical situation, as each VL offers its own set of advantages and disadvantages. We believe that VLs should become the gold standard for ETI, with several advantages highlighted over DLs. Furthermore, VLs can also allow us to transition from blind insertion techniques for procedures including temperature probes and nasogastric tubes to ‘vision-guided’ insertion, ultimately limiting the potential for wrong space insertion, with future studies potentially exploring this field.

5. Conclusions

The purpose of this review is to critically assess and compare the effectiveness of VLs in modern airway management, both in real patients and simulation scenarios involving manikins. This study was performed as an extension of our 2016 analysis, to deduce whether there were any changes in clinician preference over the past 6 years. This review highlighted similar results to our study in 2016, with the CMAC still being the most preferred for non-channelled laryngoscopes, closely followed by the GlideScope, and the Pentax AWS being the most preferred for channelled laryngoscopes based on the current literature. We hope this audit increases the awareness of both individual practitioners and departments of anaesthesia, to highlight the importance of VL use and to lay a platform for future studies to expand knowledge in this field.

Author Contributions

Conceptualisation, A.V.Z.; Methodology, I.N. and V.N.; Software, I.N. and V.N.; Validation, A.V.Z., I.N. and V.N.; Formal Analysis, I.N.; Investigation, V.N.; Resources, I.N. and V.N.; Data curation, V.N.; Writing—original draft preparation, I.N. and V.N.; Writing—review and editing, A.V.Z., I.N. and V.N.; Visualisation, V.N.; supervision, A.V.Z.; Project Administration, A.V.Z. and I.N.; Funding Acquisition, A.V.Z. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Data is contained within the article.

Acknowledgments

The authors would like to acknowledge the librarians of Gold Coast Hospital and Health Service for their support and help in this review.

Conflicts of Interest

The authors declare no conflict of interest.

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Figure 1. PRISMA identification, screening and selection of articles.
Figure 1. PRISMA identification, screening and selection of articles.
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Figure 2. Images of the most-preferred VLs. (Left to Right): CMAC (D-Blade attachment), Pentax AWS and GlideScope.
Figure 2. Images of the most-preferred VLs. (Left to Right): CMAC (D-Blade attachment), Pentax AWS and GlideScope.
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Table 1. A range of videolaryngoscopes used for airway management.
Table 1. A range of videolaryngoscopes used for airway management.
ManufacturerAddressVideolaryngoscopeBlade Type
AirAngelBlade.org, AirAngel Project Online 3D-Printed VideolaryngoscopesUSAAirAngel blade 3D-printedNon-channelled, Acute-angled
Airlangga universitySurbaya, IndonesiaWycopeNon-channelled, Acute-angled
DahlhausenKöln, GermanyDahlhausenNon-channelled, Macintosh
Industry Design Registration of Indonesia: HKI. KI.05.01.02.P00202101656 and A00202100589IndonesiaO-MacNon-channelled, Macintosh
IntersurgicalBerkshire, United KingdomI-viewNon-Channelled, Macintosh
Karl StorzTuttlingen, GermanyDCI; C-MAC; C-MAC D-blade; C-MAC Pocket Monitor; CMAC Miller bladeNon-channelled, Macintosh, Miller and Acute-angled
King Systems Ambu, A/S Ballerup, DenmarkKing Vision VL channelled; non-channelled; aBlade channelled; aBLade non-channelled; Paediatric aBladeChannelled/Non-channelled, Acute-angled
Medtronic Operational HeadquartersMinneaopolis, USAMcGrath Mac, McGrath Mac X-BladeNon-channelled, Macintosh and acute-angulated
Pentax-AWS, Hoya CorporationTokyo, JapanPentax Airway Scope Channelled
Prodol Meditec S.A.Vizcaya, SpainAirtraq; Airtraq double lumenChannelled
Salter LabsCalifornia, USAIntubrite Non-channelled, Macintosh
Smart Trach MedicareLucknow, IndiaSmart TrachNon-channelled, Acute-angled
Soma Technology InternationalBloomfield, USAMcGRATH Series 5 Non-channelled, Acute-angled
Truphatek International ltd.Netanya, IsraelTruView; Truview EVO2; Truview PCDNon-channelled, Acute-angled
Tuoren MedicalHenan, ChinaTUORen Non-channelled, Macintosh
Venner MedicalKiel, GermanyVenner APA channelled; non-channelledChannelled/Non-channelled, Macintosh and Acute-angled
Verathon MedicalBothell, WA, USAGlideScope; GlideScope Cobalt; Glidescope Advanced Video LaryngoscopeNon-channelled, Acute-angled
Vivid MedicalPalo Alto, CA, USAVividTrac VT-A100Channelled
Table 2. Outcomes of comparative studies in clinical patients using different types of videolaryngoscopes.
Table 2. Outcomes of comparative studies in clinical patients using different types of videolaryngoscopes.
YearFirst AuthorNo. of PatientsSettingIntubatorNumber and Types of Videolaryngoscopes UsedOutcomes Based On:
A: Improved Glottis View
B: Faster Time to Successful Intubation
C: Higher First Attempt Intubation Success
D: Less Use of Manoeuvres or Adjuncts
E: Other
Clinically Preferred VideolaryngoscopeBlade Type of Most-Preferred VL
2016Al-Ghamdi [8]86SurgicalAnaesthetists3: GS, AT, KV-CA: Equal
B: GS > KV-C > AT
C: Equal
D: Equal
E: Less sore throat in AT and KV-C than GS
GS for primary outcomesNon-channelled, Acute-angled
2016Alvis [9]64SurgicalAnaesthetic Staff2: McGrath Mac, KV-CA: Equal
B: McGrath Mac
C: McGrath Mac
D: Equal
McGrath MacNon-channelled, Macintosh
2016Wan [10]90Double Lumen Tube SurgicalAnaesthetists2: McGrath Series 5 (Acute), AT-DLA: Equal
B: AT
C: Equal
D: Equal
ATChannelled
2017Ahmed [11]60Surgical Difficult patients in Neutral PositionAnaesthetists2: CMAC, ATA: Equal
B: CMAC
C: Equal
D: Equal
E: Less haemodynamic changes in CMAC
CMACNon-channelled, Macintosh
2017Belze [12]72Double Lumen Tube Surgical with difficult airwayAnaesthetists2: GS, ATA: Equal
B: Equal
C: Equal
D: Equal
GS = ATGS = Non-channelled, Acute-angled

AT = Channelled
2017Kleine-Brueggeney [13]480SurgicalAnaesthetists3: KV-NC, AT, APAA: KV-NC > AT > APA
B: AT > KV-NC > APA
C: KV-NC > AT > APA
D: -
KV-NCNon-channelled, Acute-angled
2017Lee [14]140SurgicalAnaesthetists2: McGrath Mac, AWSA: AWS
B: Equal
C: Equal
D: Equal
AWSChannelled
2017Raza [15]60SurgicalAnaesthetists2: AT, McGrath A: Equal
B: AT
C: Equal
D: -
ATChannelled
2017Sato Boku [16]60Surgical Nasotracheal IntubationAnaesthetists2: McGrath Mac, AWSA: Equal
B: McGrath Mac
C: Equal
D: Equal
McGrath MacNon-channelled, Macintosh
2017Shravanalakshmi [17]135Surgical with Cervical Spine ImmobilisationAnaesthetists3: CMAC, CMAC-D, KV-NCA: KV-NC > CMAC-D
B: CMAC > CMAC-D
C: Equal
D: Equal
E: Ease of Laryngoscope insertion CMAC > KV-NC > CMAC-D
CMACNon-channelled, Macintosh
2017Singh [18]150Paediatric SurgicalAnaesthetists2: CMAC, TV-PCDA: TV-PCD
B: CMAC
C: Equal
D: TV-PCD
TV-PCDNon-channelled, Acute-angled
2017Tseng [19]105Surgical Nasotracheal IntubationAnaesthetists2: GS, AWSA: Equal
B: Equal
C: Equal
D: Equal
GS = AWSGS = Non-channelled, Acute-angled

AWS = Channelled
2017Vadi [20]93Paediatric Surgical with Cervical Spine ImmobilisationAnaesthetic Trainees2: GS-Cobalt, DCIA: Equal
B: Equal
C: Equal
D: -
GS-Cobalt = DCIGS = Non-channelled, Acute-angled

DCI = Non-channelled, Macintosh
2017Vargas [21]42Surgical Difficult AirwayAnaesthetists2: Imago-V-C, GSA: Equal
B: Equal
C: Equal
D: Imago-V
E: Less force required with Imago-V-C
Imago-V-CChannelled
2018Abdelgalel [22]120Intensive Care UnitICU Physicians2: GS, ATA: Equal
B: Equal
C: Equal
D: -
GS = ATGS = Non-channelled, Acute-angled

AT = Channelled
2018Ajimi [23]60Double Lumen Tube SurgicalAnaesthetists2: AT, AWSA: Equal
B: AT
C: Equal
D: -
ATChannelled
2018Cavus [24]168Pre-hospitalEmergency Physicians3: CMAC-PM, KV-C, APAA: Equal
B: Equal
C: CMAC-PM + APA > KV-C
D: -
E: Handling concerns with KV-C
CMAC-PM + APACMAC-PM = Non-channelled, Acute-angled

APA = Non-channelled, Macintosh
2018Chanchayanon [25]40SurgicalAnaesthetic Residents2: GS, McGrath Series 5 (Acute)A: Equal
B: GS
C: Equal
D:-
GSNon-channelled, Acute-angled
2018El-Tahan [26]133Double Lumen Tube SurgicalAnaesthetists3: GS, AT, KV-CA: Equal
B: AT > GS
C: Equal
D: AT > GS
ATChannelled
2018Gupta [27]80Surgical Neonates and InfantsAnaesthetists2: CMAC-Miller, TV-PCDA: Equal
B: CMAC-Miller
C: CMAC-Miller
D: AT > GS
CMAC-MillerNon-channelled, Miller
2018Mendonca [28]200Surgical Neutral and ‘Sniffing’Anaesthetists2: KV-C, CMAC-DA: KV-C > CMAC-D in Neutral
B: Equal
C: Equal
D: -
E: Modified Difficult Intubation Score Equal
KV-C Channelled
2018Mishra [29]80Nasotracheal Intubation SurgicalAnaesthetists2: KV-NC, TV-PCDA: Equal
B: Equal
C: Equal
D: Equal
KV-NC = TV-PCDKV-NC = Non-channelled, Acute-angled

TV-PCD = Non-channelled, Acute-angled
2018Yoo [30]106Paediatric Nasotracheal IntubationAnaesthetists2: AWS, McGrath MacA: Equal
B: Equal
C: Equal
D: Equal
AWS = McGrath MacAWS = Channelled

McGrath Mac = Non-channelled Macintosh
2019Akbas [31]80Morbidly Obese SurgicalAnaesthetists2: McGrath Mac, CMACA: Equal
B: CMAC
C: Equal
D: Equal
E: Better Haemodynamic Response in CMAC
CMACNon-channelled, Macintosh
2019Blajic [32]180Obstetric CaesareansAnaesthetists2: CMAC, KV-CA: KV-C
B: Equal
C: Equal
D: CMAC
E: Easier to use
CMACNon-channelled, Macintosh
2019Chae [33]123Nasotracheal Intubation SurgicalAnaesthetists2: AWS, McGrath MacA: McGrath Mac
B: Equal
C: Equal
D: Equal
McGrath MacNon-channelled, Macintosh
2019Markham [34]225Anticipated Difficult Airway SurgicalAnaesthetic Residents3: GS-AVL, KV-C, KV-NCA: Equal
B: Equal
C: GS-AVL + KV-NC > KV-C
D: Equal
GS-AVL + KV-NCGS-AVL = Non-channelled, Acute-angled

KV-NC = Non-channelled, Acute-angled
2019Roh [35]120Nasotracheal Intubation with Manual In-line Stabilisation SurgicalAnaesthetists2: AWS, McGrath MacA: Equal
B: McGrath Mac
C: Equal
D: Equal
E: Less Bleeding McGrath Mac
McGrath MacNon-channelled, Macintosh
2019Sahajanandan [36]63Anticipated Difficult Airway in Obese Patients SurgicalAnaesthetists2: KV-C, CMAC-DA: Equal
B: Equal
C: CMAC-D
D: -
CMAC-DNon-channelled, Acute-angled
2019Suzuki [37]287Emergency Intubation Emergency Department and Intensive Care UnitEmergency Physicians, Intensive Care Physicians, Anaesthetists and Residents3: KV-C, AWS, McGrath MacA: -
B: Equal
C: AWS + McGrath Mac > KV-C
D: -
AWS + McGrath MacAWS = Channelled

McGrath Mac = Non-channelled, Macintosh
2019Zhu [38]94Nasotracheal Intubation Anticipated Difficult AirwayAnaesthetists2: KV-NC, McGrath Mac (acute)A: Equal
B: Equal
C: Equal
D: Equal
KV-NC = McGrath MacNon-channelled, Acute-angled

McGrath Mac = Non-channelled, Macintosh
2020Brozek [39]110Obese Patients SurgicalAnaesthetists2: KV-C, GSA: Equal
B: Equal
C: GS
D: Equal
GSNon-channelled, Acute-angled
2020Huang [40]89Double Lumen Tube SurgicalAnaesthetists2: GS, CMAC-DA: CMAC-D
B: CMAC-D
C: Equal
D: CMAC-D
CMAC-DNon-channelled, Acute-angled
2020Kaur [41]120SurgicalAnaesthetists2: McGrath Mac, TVA: Equal
B: Equal
C: Equal
D: Equal
McGrath Mac = TVMcGrath Mac = Non-channelled, Macintosh

TV = Non-channelled, Acute-angled
2020Pappu [42]120Surgical Difficult AirwayAnaesthetists2: TV-EVO2, CMAC-DA: Equal
B: CMAC-D
C: -
D: CMAC-D
CMAC-DNon-channelled, Acute-angled
2020Sen [43]60Surgical with Cervical Spine ImmobilisationAnaesthetists2: TV, KV-NCA: Equal
B: KV-NC
C: Equal
D:-
E: Easier Intubation with KV-NC
KV-NCNon-channelled, Acute-angled
2021Chandrashekaraiah [44]60SurgicalAnaesthetists2: GS, CMAC-DA: Equal
B: GS
C: Equal
D: -
GSNon-channelled, Acute-angled
2021Chandy [45]100Surgical with Cervical Spine ImmobilisationAnaesthetists2: KV-C, CMAC-DA: -
B: Equal
C: Equal
D: KV-C
E: KV-C Easier
KV-CChannelled
2021Gupta [46]140Neonates and Infants SurgicalAnaesthetists2: CMAC-Miller, McGrath MacA: CMAC-Miller
B: Equal
C: Equal
D: -
CMAC-MillerNon-channelled, Miller
2021Mani [47]116Surgical with Manual In-line StabilisationAnaesthetists2: CMAC-D, ATA: Equal
B: Equal
C: Equal
D: CMAC-D
CMAC-DNon-channelled, Acute-angled
2021Sepmiko [48]270SurgicalAnaesthetists2: O-Mac, McGrath MacA: Equal
B: O-Mac
C: O-Mac
D: O-Mac
O-MacNon-channelled, Macintosh
2021Sultana [49]120Surgical in Lateral PositionAnaesthetists2: CMAC, ATA: Equal
B: CMAC
C: Equal
D: Equal
CMACNon-channelled, Macintosh
2021Teo [50]65SurgicalAnaesthetists2: CMAC, GS A: Equal
B: CMAC > GS
C: Equal
D: Equal
CMAC Non-channelled, Macintosh
2022Gupta [51]60SurgicalAnaesthetists (COVID PPE)2: CMAC, McGrath MacA: Equal
B: Equal
C: Equal
D: Equal
CMAC = McGrath MacCMAC = Non-channelled, Macintosh

McGrath Mac = Non-channelled, Macintosh
2022Haldar [52]375SurgicalAnaesthetists2: CMAC, STA: -
B: CMAC > ST
C: Equal
D: Equal
E: CMAC > ST Lifting force
CMAC Non-channelled, Macintosh
2022Jayadi [53]63SurgicalAnaesthetic residents2: CMAC, WycopeA: -
B: Equal
C: -
D: Equal
CMAC = WycopeCMAC = Non-channelled, Macintosh

Wycope = Non-channelled, Acute-angled
2022Karadag [54]100SurgicalAnaesthetists2: McGrath (acute), CMAC A: Equal
B: Equal
C: Equal
D: Equal
McGrath = CMACCMAC = Non-channelled, Macintosh

McGrath Mac = Non-channelled, Acute-angled
2022Kumar [55]140SurgicalAnaesthetists2: McGrath Mac, KV-CA: Equal
B: McGrath Mac > KV
C: Equal
D: Equal
McGrath MacNon-channelled, Macintosh
2022Suryatheja [56]160SurgicalAnaesthetic Residents2: CMAC Miller blade size 1, CMAC Macintosh Blade size 2A: Equal
B: Equal
C: Equal
D: CMAC Mac > CMAC Mil
CMAC MacNon-channelled, Macintosh
2022Zhang [57]210SurgicalAnaesthetists2: McGrath Mac-X, CMACA: McGrath Mac-X > CMAC
B: CMAC > McGrath Mac-X
C: Equal
D: Equal
McGrath Mac-X = CMACMcGrath Mac-X = Non-Channelled, Acute-angled

CMAC = Non-channelled, Macintosh
APA = Venner AP advance; AT = Airtraq; AT-DL = Airtraq double lumen; AWS = Pentax Airway Scope; CMAC = CMAC; CMAC-D = CMAC D blade; CMAC Miller = CMAC Miller blade; CMAC-PM = CMAC pocket monitor; Dahlhausen = Dahlhausen; DCI = Storz-DCI; GS = GlideScope; GS-AVL = GlideScope Advanced Video Laryngoscope; GS Cobalt = GlideScope Cobalt; Imago-V-C = Imago channelled V blade; IB = Intubrite; KV = King Vision; KV-C = King Vision channelled; KV-NC = King Vision non-channelled; KV-aBlade-C = King Vision aBlade channelled; KV-aBlade-NC = King Vision aBlade non-channelled; KV paeds aBlade = King Vision Paediatric aBlade; McGrath Mac = McGrath Mac; McGrath Mac (acute) = McGrath Mac acute-angled blade; McGrath Series 5 (acute) = McGrath Series 5 acute-angled blade; McGrath Mac-X = McGrath Mac X-blade; O-Mac = O-Mac; ST = Smart Trach; TV-PCD = Truview PCD; TV = Truview; TV EVO2 = Truview EVO2; Wycope = Wycope.
Table 3. Outcomes of comparative studies in simulation studies using different types of videolaryngoscopes.
Table 3. Outcomes of comparative studies in simulation studies using different types of videolaryngoscopes.
YearFirst AuthorNo. of ProvidersSimulation SettingIntubatorNumber and Types of Videolaryngoscopes UsedOutcomes Based On:
A: Improved Glottis View
B: Faster Time to Successful Intubation
C: Higher First Attempt Intubation Success
D: Less Use of Manoeuvres or Adjuncts
E: Other
Clinically Preferred VideolaryngoscopeBlade of Most-Preferred VL
2016Altun [58]41Difficult ManikinAnaesthetic Residents2: McGrath Mac (acute), CMACA: CMAC
B: CMAC
C: CMAC
D: CMAC
CMACNon-channelled, Macintosh
2016Arslan [59]36Difficult Paediatric ManikinMedical Students2: GS, ATA: -
B: -
C: GS
D: GS
GSNon-channelled, Acute-angled
2016El-Tahan [60]21Double Lumen Tube ManikinAnaesthetists3: GS, AT, KV-NCA: Equal
B: Equal
C: Equal
D: GS > KV-NC
E: GS Preferred over AT and KV-NC
GSNon-channelled, Acute-angled
2016Hippard [61]30Paediatric ManikinAnaesthetists2: TV-PCD, GS-CobaltA: -
B: Equal
C: Equal
D: -
TV-PCD = GS-CobaltTV-PCD = Non-channelled, Acute-angled

GS-Cobalt = Non-channelled, Acute-angled
2016Kim [62]35ManikinPhysicians3: AWS, GSA: GS
B: Equal
C: GS
D: -
GSNon-channelled, Acute-angled
2016Kim [63]21ManikinPhysicians2: AWS, GSA: Equal
B: AWS
C: Equal
D: -
AWSChannelled
2016Nakanishi [64]35ManikinPhysicians2: AWS, CMACA: Equal
B: AWS
C: Equal
D: -
E: Higher Force on Incisors with CMAC than AWS
AWSChannelled
2016Schröder [65]42Manikin wearing chemical protective gearAnaesthetists3: AT, GS, AP AdvanceA: AP Advance > AT and GS
B: AP Advance > AT and GS
C: -
D: -
E: Preferred AP Advance > GS > AT
AP AdvanceChannelled
2016Shin [66]39ManikinNovice Medical Students2: McGrath Mac, CMACA: Equal
B: Equal
C: Equal
D: Equal
E: Preferred McGrath Mac
McGrath MacNon-channelled, Macintosh
2017Hodnick [67]5CadaverParamedics2: GS, VTA: Equal
B: Equal
C: Equal
D: Equal
GS = VTGS = Non-channelled, Acute-angled

VT = Channelled
2017Lee [68]18Manikin with Normal and Difficult AirwayParamedics4: GS, AWS, KV-NC, KV-CA: Equal
B: AWS
C: Equal
D: -
E: Preferred AWS
AWSChannelled
2017Owada [69]20Paediatric Manikin with Difficult AirwayAnaesthetists2: AT, McGrath MacA: AT
B: Equal
C: AT
D: -
E: AT Preferred and less dental trauma
ATChannelled
2018Kriege [70]80Infant Manikin Normal and Difficult AirwayAnaesthetic Staff and Paediatric Critical Care Medicine Staff2: KV-Paeds aBlade, CMAC-DA: KV-Paeds aBlade
B: KV-Paeds aBlade
C: KV-Paeds aBlade
D: -
KV-Paeds aBladeNon-Channelled, Acute-angled
2018Oshika [71]21Prone ManikinAnaesthetists2: AWS, McGrath MacA: -
B: AWS
C: AWS
D: -
AWSChannelled
2019Chew [72]105Difficult Airway ManikinJunior Doctors3: KV-aBlade-C, KV-aBlade-NC, Mcgrath MacA: -
B: KV-aBlade-C + McGrath Mac > KV-aBlade-NC
C: KV-aBlade-C + McGrath Mac > KV-aBlade-NC
D: -
KV-aBlade-C + McGrath Mac KV-aBlade-C = Channelled

McGrath Mac = Non-channelled, Macintosh
2019Desai [73]26Paediatric Pierre Robin Sequence ManikinPaediatric Intensive Care Physicians2: AT, GSA: Equal
B: AT
C: AT
D: -
ATChannelled
2019Raimann [74]42Trapped Car Crash ManikinAnaesthetic Staff and Emergency Physicians4: CMAC-D, TV-PCD, CMAC, CMAC-PMA: CMAC-D > TV-PCD
B: CMAC > TV-PCD + CMAC-D, CMAC-PM > TV-PCD
C: CMAC + CMAC-PM > TV-PCD
D: -
E: CMAC Preferred
CMACNon-channelled, Macintosh
2020Gaszyński [75]11Prone and Sitting ManikinAnaesthetists2: AWS, IB A: Equal
B: AWS
C: Equal
D: -
E: Lower pressure with AWS
AWSChannelled
2020Moritz [76]112Difficult Airway ManikinAnaesthetist and Paramedics4: I-View, KV-NC, GS, DahlhausenA: KV-NC, GS, Dahlhausen > I-View
B: KV-NC, GS, Dahlhausen > I-View
C: KV-NC, GS, Dahlhausen > I-View
D: -
E: Preferred GS
GSNon-channelled, Acute-angled
2020Romito [77]8Cadaver with Cervical Spine InstabilityAnaesthetists3: CMAC-D, GS, McGrath Mac-XA: Equal
B: -
C: Equal
D: -
CMAC-D = GS = McGrath Mac-XCMAC-D = Non-channelled, Acute-angled
GS = Non-channelled, Acute-angled
McGrath Mac-X = Non-channelled, Acute-angled
2020Votruba [78]58Manikin with Cervical Spine ImmbolisationAnaesthetists2: KV-C, KV-NCA: Equal
B: KV-C
C: KV-C
D:-
E: Easier with KV-C
KV-CChannelled
2020 Yi [79]35Manikin with Normal Neck and with Cervical Spine InstabilityAnaesthetic Nurses2: McGrath Mac, AWSA: Equal
B: Equal
C: Equal
D: -
McGrath Mac = AWSMGrath Mac = Non-channelled, Macintosh
AWS = Channelled
2021Ataman [80]23Manikin with Normal and Difficult AirwayEmergency Physicians and Emergency Residents2: GS, AirAngel 3D-PrintedA: -
B: GS
C: GS
D: -
GSNon-channelled, Acute-angled
2021Decamps [81]79Critical Illness ManikinResidents4: KV-C, AWS, AT, VTA: KV-C + AWS > VT
B: AWS > VT
C: Equal
D: Equal
E: Ease of use with KV-C + AWS + AT > VT
AWSChannelled
2021Gupta [82]50COVID Simulation ManikinAnaesthetist and Non-Anaesthetic Physicians2: KV-C, TuorenA: KV-C
B: KV-C
C: KV-C
D: KV-C
E: Easier and less complications with KV-C
KV-CChannelled
2021Moritz [83]86Paediatric Pierre Robin Sequence ManikinAnaesthetists2: GS-Core, CMAC-MillerA: GS
B: CMAC-Miller
C: Equal
D: CMAC-Miller
E: CMAC-Miller preferred by both anaesthetist with experience and with limited experience
CMAC-MillerNon-channelled, Miller
2021Taylor [84]33ManikinMilitary emergency providers2: I-view, GS A: GS > I-view
B: GS > I-view
C: Equal
D: -
GS Non-channelled, Acute-angled
2021Vig [85]30ManikinMedical Professionals (no intubation experience)2: McGrath Mac, CMAC A: CMAC > McGrath
B: Equal
C: Equal
D: Equal
CMACNon-channelled, Macintosh
2022Gupta [86]100ManikinMedical Students2: KV-C, KV-NC A: Equal
B: KV-C > KVNC
C: KV-C > KVNC
D:-
E: KV-C > KVNC ease of intubation
KV-C Channelled
2022Er [87]50ManikinPaediatric Residents2: McGrath Mac, CMAC PMA: CMAC PM > McGrath Mac
B: CMAC PM > McGrath Mac
C: CMAC PM > McGrath
D:-
CMACNon-channelled, Macintosh
2022Kumar [88]61ManikinHealthcare Staff with COVID PPE2: CMAC, KV-CA: Equal
B: Equal
C: Equal
D: Equal
E: CMAC > KV-C—easier insertion of laryngoscope blade
CMAC Non-channelled, Macintosh
AirAngel 3D-printed = AirAngel blade 3D-printed; APA = Venner AP advance; AWS = Pentax Airway Scope; AT = Airtraq; CMAC = CMAC; CMAC-D = CMAC D blade; CMAC Miller = CMAC Miller blade; CMAC-PM = CMAC pocket monitor; GS = GlideScope; GS Cobalt = GlideScope Cobalt; GS-Core = GlideScope Core; I-view = I-view; KV-aBlade-C = King Vision aBlade channelled; KV-aBlade-NC = King Vision aBlade non-channelled; KV-C = King Vision channelled; KV-NC = King Vision non-channelled; KV paeds aBlade = King Vision Paediatric aBlade; McGrath Mac = McGrath Mac; McGrath Mac (acute) = McGrath Mac acute-angled blade; Tuoren = TUORen; TV-PCD = Truview PCD; VT = VividTrac VT-A100.
Table 4. Outcomes of videolaryngoscopy studies listed by most-preferred VLs.
Table 4. Outcomes of videolaryngoscopy studies listed by most-preferred VLs.
SurgicalSimulationTotal
VLSSurgical StudiesFavoured Studies% of Studies FavouredTotal Number of Patients in StudiesSimulation StudiesFavoured Studies% of Studies FavouredTotal Number of Participants in StudiesTotal StudiesFavoured% Favoured
CMAC251976%289412758%472372670%
McGrath191263%23049444%349281657%
GS13969%124014964%496271867%
KV-NC6583%10747114%49413646%
AWS8450%10018788%255161169%
AT11654%13976233%22417847%
KV-C12217%17567457%47119632%
CMAC = CMAC; CMAC D-blade; CMAC Miller blade; CMAC Pocket Monitor; McGrath = McGrath Mac; McGrath Series 5; McGrath Mac X-blade; GS = GlideScope; GlideScope Cobalt; GlideScope Advanced Video Laryngoscope; KV-NC = King Vision non-channelled; King Vision aBlade non-channelled; King Vision Paediatric aBlade; AWS = Pentax Airway Scope; AT = Airtraq; Airtraq double lumen; KV-C = King Vision channelled; King Vision aBlade channelled.
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Nedunchezhian, V.; Nedunchezhian, I.; Van Zundert, A. Clinically Preferred Videolaryngoscopes in Airway Management: An Updated Systematic Review. Healthcare 2023, 11, 2383. https://doi.org/10.3390/healthcare11172383

AMA Style

Nedunchezhian V, Nedunchezhian I, Van Zundert A. Clinically Preferred Videolaryngoscopes in Airway Management: An Updated Systematic Review. Healthcare. 2023; 11(17):2383. https://doi.org/10.3390/healthcare11172383

Chicago/Turabian Style

Nedunchezhian, Vikram, Ishvar Nedunchezhian, and André Van Zundert. 2023. "Clinically Preferred Videolaryngoscopes in Airway Management: An Updated Systematic Review" Healthcare 11, no. 17: 2383. https://doi.org/10.3390/healthcare11172383

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