A Review of Radiomics in Predicting Therapeutic Response in Colorectal Liver Metastases: From Traditional to Artificial Intelligence Techniques
Abstract
:1. Introduction
2. Background
3. Literature Review and Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Study Reference | CT Scan Acquisition Parameters | |||||
---|---|---|---|---|---|---|
Scanner Type (Detector Rows) | Tube Voltage (kVp) | Radiation Dose (mAs) | Slice Thickness | Scanner Phase | Contrast | |
[29] | 4 or 16 slices | NM | NM | NM | triphasic liver phase or single phase | Ioversol |
[16] | 16-slice or 64-slice | NM | NM | 3 mm | PVP | NM |
[11] | 64-slice 16-slice 8-slice | 120 kVp 120 kVp 120 kVp | 200 mAs 200 mAs 250 mAs | 3 mm 3 mm 2.5 mm | arterial and PVP phases PVP_ONLY | 370 mgI/mL iopromide |
[12] | 64-slice | 100 kVp–120 kVp | NM | 3 mm or 5 mm | (PVP) | 300 mgI/mL iopromide |
[30] | 256-slice | 100 kVp or 120 kVp | 100 mAs | 5 mm | Non-contrast enhanced DCE-CT peak arterial enhancement DCE-CT (PVP) | 320 mgI/mL Or 350 mgI/mL iodixanol |
[31] | 128-slice | 120 kVp | 210 mAs | 5mm | NM | 350 mgI/mL Iomeron |
[32] | NM | NM | NM | 3mm or 5mm | (PVP) | NM |
[19] | NM | 122 ± 6 kVp | 242 ± 99 mAs | 5.1 ± 1.0 mm | (PVP) | NM |
[26] | NM | NM | NM | NM | (PVP) | NM |
[47] | NM | NM | NM | NM | (PVP) | NM |
[48] | iCT 256/IQon Spectral CT/Brilliance 64 | NM | NM | 3–5 mm | (PVP) | 600 mgI/kg Iopamiron |
[49] | Brilliance iCT | 120 kVp | 240–400 mAs | 5 mm | (PVP) | 100 mL Iopromide 370 mg/mL |
Study | Dataset Size | Targeted Chemotherapy | Segmentation Method | Feature Extraction Tool | Extracted Features |
---|---|---|---|---|---|
[29] | 50 patients | Chemotherapy and bevacizumab | NM | NM | Studies vary in measuring different radiomics features such as mean-intensity value, entropy, uniformity, histogram parameters, grey-level co-occurrence matrix, and other radiomics |
[16] | 21 patients | Capecitabine plus oxaliplatin (XELOX) | Manually | MATLAB Script | |
[11] | 145 patients | FOLFOX * FOLFIRI * | Manually | Medical Imaging Solution ^ | |
[12] | 70 patients | Different regimens | Manually | In house-software written in Python (Pyradiomics package) | |
[30] | 27 patients | Bevacizumab and regorafenib | Intellispace 6.0 (ISP) ^^ | TexRAD | |
[31] | 43 patients | FOLFOX ** FOLFIRI ** Alone or with bevacizumab | Manually | MATLAB Script | |
[32] | 230 patients | FOLFIRI * and bevacizumab) | Manually | TexRAD software | |
[19] | 667 patients | FOLFIRI * and cetuximab | Counters were drawn semi-automatically | MATLAB script | |
[26] | 24 patients | NM | Manual | NM | |
[47] | 24 patients | NM | Automatic | NM | |
[48] | 42 Patients | Oxaliplatin | Manual | 3D slicer tool | |
[49] | 192 patents | oxaliplatin (CAPEOX or mFOLFOX6) or irinotecan (FOLFIRI or XELIRI) | Manual | Pyradiomics Package |
Main Common Limitations |
---|
Small dataset and data inconsistency: In most studies, external validation was required because they were retrospective studies conducted for a single institution. There was a difference in treatment among the patients. |
Manual segmentation: One reader (without taking into account interobserver variation) performed an image segmentation. Subject bias. There is no standard method for determining the size of lesions. |
More evaluation is required: The texture measurements were not retested to assess their repeatability. A single metastatic lesion was evaluated. It was only possible to extract features from the large lesion and not from all metastases. It is important to note that not all texture features were analyzed. |
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Alshohoumi, F.; Al-Hamdani, A.; Hedjam, R.; AlAbdulsalam, A.; Al Zaabi, A. A Review of Radiomics in Predicting Therapeutic Response in Colorectal Liver Metastases: From Traditional to Artificial Intelligence Techniques. Healthcare 2022, 10, 2075. https://doi.org/10.3390/healthcare10102075
Alshohoumi F, Al-Hamdani A, Hedjam R, AlAbdulsalam A, Al Zaabi A. A Review of Radiomics in Predicting Therapeutic Response in Colorectal Liver Metastases: From Traditional to Artificial Intelligence Techniques. Healthcare. 2022; 10(10):2075. https://doi.org/10.3390/healthcare10102075
Chicago/Turabian StyleAlshohoumi, Fatma, Abdullah Al-Hamdani, Rachid Hedjam, AbdulRahman AlAbdulsalam, and Adhari Al Zaabi. 2022. "A Review of Radiomics in Predicting Therapeutic Response in Colorectal Liver Metastases: From Traditional to Artificial Intelligence Techniques" Healthcare 10, no. 10: 2075. https://doi.org/10.3390/healthcare10102075