Endothelial and Hemodynamic Function in a Large Animal Model in Relation to Different Extracorporeal Membrane Oxygenation Cannulation Strategies and Intra-Aortic Balloon Pumping
Abstract
:1. Introduction
2. Materials and Methods
2.1. Experimental Setting
2.2. In Vitro Endothelial Function
2.3. Statistical Analysis
3. Results
3.1. Comparison of Peripheral and Central ECMO
3.2. Comparison of Peripheral and Central ECMO with IABP
3.3. Peripheral ECMO with and without IABP
3.4. Central ECMO with or without IABP
4. Discussion
4.1. Endothelial Function
4.2. Hemodynamic Assessment
5. Limitations
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Experimental Settings | |||||
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Group | Control | pECMO | cECMO | pECMO and IABP | cECMO and IABP |
Type of mechanical support | None | ECMO with peripheral canulation | ECMO with central canulation | ECMO with peripheral canulation plus IABP | ECMO with central canulation plus IABP |
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Gerfer, S.; Djordjevic, I.; Maier, J.; Movahed, A.; Elskamp, M.; Kuhn, E.; Liakopoulos, O.; Wahlers, T.; Deppe, A.C. Endothelial and Hemodynamic Function in a Large Animal Model in Relation to Different Extracorporeal Membrane Oxygenation Cannulation Strategies and Intra-Aortic Balloon Pumping. J. Clin. Med. 2023, 12, 4038. https://doi.org/10.3390/jcm12124038
Gerfer S, Djordjevic I, Maier J, Movahed A, Elskamp M, Kuhn E, Liakopoulos O, Wahlers T, Deppe AC. Endothelial and Hemodynamic Function in a Large Animal Model in Relation to Different Extracorporeal Membrane Oxygenation Cannulation Strategies and Intra-Aortic Balloon Pumping. Journal of Clinical Medicine. 2023; 12(12):4038. https://doi.org/10.3390/jcm12124038
Chicago/Turabian StyleGerfer, Stephen, Ilija Djordjevic, Johanna Maier, Ana Movahed, Mara Elskamp, Elmar Kuhn, Oliver Liakopoulos, Thorsten Wahlers, and Antje C. Deppe. 2023. "Endothelial and Hemodynamic Function in a Large Animal Model in Relation to Different Extracorporeal Membrane Oxygenation Cannulation Strategies and Intra-Aortic Balloon Pumping" Journal of Clinical Medicine 12, no. 12: 4038. https://doi.org/10.3390/jcm12124038