Single-Center Retrospective Subgroup Analysis of “Primary Aortic” (Aneurysm, Aortic Dissection, PAU) and “Secondary Aortic” (Iatrogenic, Trauma, Aortoesophageal Fistula) Indications for Emergency TEVAR
Abstract
:1. Introduction
2. Methods
3. Results
3.1. Demographics and Clinical Characteristics
3.2. Etiology, Classification, Laboratory Values and Outcomes
3.3. Independent Factors Associated with Early Death and Postoperative Morbidity
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Volodos, N.L.; Karpovich, I.P.; Shekhanin, V.E.; Troian, V.I.; Iakovenko, L.F. A case of distant transfemoral endoprosthesis of the thoracic artery using a self-fixing synthetic prosthesis in traumatic aneurysm. Grud. Khir. 1988, 84–86. [Google Scholar]
- Parodi, J.C. Endovascular repair of aortic aneurysms, arteriovenous fistulas, and false aneurysms. World J. Surg. 1996, 20, 655–663. [Google Scholar] [CrossRef] [PubMed]
- Dake, M.D.; Miller, D.C.; Semba, C.P.; Mitchell, R.S.; Walker, P.J.; Liddell, R.P. Transluminal placement of endovascular stent-grafts for the treatment of descending thoracic aortic aneurysms. N. Engl. J. Med. 1994, 331, 1729–1734. [Google Scholar] [CrossRef] [Green Version]
- Vilacosta, I.; Roman, J.A. Acute aortic syndrome. Heart 2001, 85, 365–368. [Google Scholar] [CrossRef]
- Demetriades, D.; Velmahos, G.C.; Scalea, T.M.; Jurkovich, G.J.; Karmy-Jones, R.; Teixeira, P.G.; Hemmila, M.R.; O’Connor, J.V.; McKenney, M.O.; Moore, F.O.; et al. Operative Repair or Endovascular Stent Graft in Blunt Traumatic Thoracic Aortic Injuries: Results of an American Association for the Surgery of Trauma Multicenter Study. J. Trauma 2008, 64, 561–571. [Google Scholar] [CrossRef] [Green Version]
- Dubose, J.J.; Leake, S.S.; Brenner, M.; Pasley, J.; Callaghan, T.O.; Luo-Owen, X.; Trust, M.D.; Mooney, J.; Zhao, F.Z.; Azizzadeh, A.; et al. Contemporary management and outcomes of blunt thoracic aortic injury: A multicenter retrospective study. J. Trauma Acute Care Surg. 2015, 78, 360–369. [Google Scholar] [CrossRef] [Green Version]
- Pang, D.; Hildebrand, D.; Bachoo, P. Thoracic endovascular repair (TEVAR) versus open surgery for blunt traumatic thoracic aortic injury. Cochrane Database Syst. Rev. 2019, 2019, CD006642. [Google Scholar] [CrossRef]
- Mousa, A.Y.; Dombrovskiy, V.Y.; Haser, P.B.; Graham, A.M.; Vogel, T.R. Thoracic Aortic Trauma: Outcomes and Hospital Resource Utilization after Endovascular and Open Repair. Vascular 2010, 18, 250–255. [Google Scholar] [CrossRef]
- Lee, W.A.; Matsumura, J.S.; Mitchell, R.S.; Farber, M.A.; Greenberg, R.K.; Azizzadeh, A.; Murad, M.H.; Fairman, R.M. Society for vascular surgery® documents endovascular repair of traumatic thoracic aortic injury: Clinical practice guidelines of the Society for Vascular Surgery. J. Vasc. Surg. 2011, 53, 187–192. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Murad, M.H.; Rizvi, A.Z.; Malgor, R.; Carey, J.; Alkatib, A.A.; Erwin, P.J.; Lee, W.A.; Fairman, R.M. Comparative effectiveness of the treatments for thoracic aortic transaction. J. Vasc. Surg. 1997, 53, 193–199.e21. [Google Scholar] [CrossRef] [Green Version]
- Jonker FH, W.; Verhagen HJ, M.; Mojibian, H.; Davis, K.A.; Moll, F.L.; Muhs, B.E.; Haven, N. Aortic endograft sizing in trauma patients with hemodynamic instability. J. Vasc. Surg. 2009, 52, 39–44. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Xenos, E.S.; Abedi, N.N.; Davenport, D.L.; Minion, D.J.; Hamdallah, O.; Sorial, E.E.; Endean, E.D. From the Southern Association for Vascular Surgery Meta-analysis of endovascular vs open repair for traumatic descending thoracic aortic rupture. J. Vasc. Surg. 2007, 48, 1343–1351. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Xenos, E.S.; Minion, D.J.; Davenport, D.L.; Hamdallah, O.; Abedi, N.N.; Sorial, E.E.; Endean, E.D. Endovascular versus open repair for descending thoracic aortic rupture: Institutional experience and meta-analysis. Eur. J. Cardio-Thorac. Surg. 2009, 35, 282–286. [Google Scholar] [CrossRef] [PubMed]
- Jonker, F.H.; Trimarchi, S.; Verhagen, H.J.; Moll, F.L.; Sumpio, B.E.; Muhs, B.E. Meta-analysis of open versus endovascular repair for ruptured descending thoracic aortic aneurysm. J. Vasc. Surg. 2010, 51, 1026–1032. [Google Scholar] [CrossRef] [Green Version]
- Harky, A.; Bleetman, D.; Chan, J.S.; Eriksen, P.; Chaplin, G.; MacCarthy-Ofosu, B.; Theologou, T.; Ambekar, S.; Roberts, N.; Oo, A. A systematic review and meta-analysis of endovascular versus open surgical repair for the traumatic ruptured thoracic aorta. J. Vasc. Surg. 2020, 71, 270–282. [Google Scholar] [CrossRef] [Green Version]
- Zhang, H.; Wang, Z.-W.; Zhou, Z.; Hu, X.-P.; Wu, H.-B.; Guo, Y. Endovascular Stent-Graft Placement or Open Surgery for the Treatment of Acute Type B Aortic Dissection: A Meta-Analysis. Ann. Vasc. Surg. 2012, 26, 454–461. [Google Scholar] [CrossRef]
- Hajibandeh, S.; Hajibandeh, S.; Antoniou, S.A.; Torella, F.; Antoniou, G.A. Revascularisation of the left subclavian artery for thoracic endovascular aortic repair. Cochrane Database Syst. Rev. 2016, 2016, CD011738. [Google Scholar] [CrossRef]
- Salsano, A.; Salsano, G.; Spinella, G.; Zaottini, F.; Mavilio, N.; Perocchio, G.; Pane, B.; Ricci, D.; Pratesi, G.; Castellan, L.; et al. Endovascular Versus Open Surgical Repair for Ruptured Descending Aortic Pathologies: A Systematic Review and Meta-Analysis of Observational Studies. CardioVascular Interv. Radiol. 2021, 44, 1709–1719. [Google Scholar] [CrossRef]
- Jordan, F.; FitzGibbon, B.; Kavanagh, E.P.; McHugh, P.; Veerasingam, D.; Sultan, S.; Hynes, N. Endovascular versus open surgical repair for complicated chronic Type B aortic dissection. Cochrane Database Syst. Rev. 2021, 12, CD012992. [Google Scholar] [CrossRef]
- Howard, C.; Sheridan, J.; Picca, L.; Reza, S.; Smith, T.; Ponnapalli, A.; Calow, R.; Cross, O.; Iddawela, S.; George, M.; et al. TEVAR for complicated and uncomplicated type B aortic dissection—Systematic review and meta-analysis. J. Card. Surg. 2021, 36, 3820–3830. [Google Scholar] [CrossRef]
- Chiesa, R.; Melissano, G.; Marone, E.M.; Marrocco-Trischitta, M.M.; Kahlberg, A. Aorto-oesophageal and aortobronchial fistulae following thoracic endovascular aortic repair: A national survey. Eur. J. Vasc. Endovasc. Surg. Off. J. Eur. Soc. Vasc. Surg. 2010, 39, 273–279. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Takeno, S.; Ishii, H.; Nanashima, A.; Nakamura, K. Aortoesophageal fistula: Review of trends in the last decade. Surg. Today 2020, 50, 1551–1559. [Google Scholar] [CrossRef] [PubMed]
- Luehr, M.; Etz, C.D.; Nozdrzykowski, M.; Garbade, J.; Lehmkuhl, L.; Schmidt, A.; Misfeld, M.; Borger, M.A.; Mohr, F.W. Emergency open surgery for aorto-oesophageal and aorto-bronchial fi stulae after thoracic endovascular aortic repair: A single-centre experience. Eur. J. Cardio-Thorac. Surg. 2015, 47, 374–383. [Google Scholar] [CrossRef] [Green Version]
- Kahlberg, A.; Tshomba, Y.; Marone, E.M.; Castellano, R.; Melissano, G.; Chiesa, R. Current Results of a Combined Endovascular and Open Approach for the Treatment of Aortoesophageal and Aortobronchial Fistulae. Ann. Vasc. Surg. 2014, 28, 1782–1788. [Google Scholar] [CrossRef]
- Kaushik, S.; Quencer, K.; Kraiss, L.W. Aortoesophageal fistula treated with emergent thoracic stent grafting. J. Vasc. Surg. Cases Innov. Tech. 2021, 7, 396–398. [Google Scholar] [CrossRef] [PubMed]
- Matono, S.; Fujita, H.; Tanaka, T.; Nagano, T.; Nishimura, K.; Murata, K.; Onitsuka, S.; Tanaka, A.; Akashi, H.; Shirouzu, K. Thoracic endovascular aortic repair for aortic complications after esophagectomy for cancer: Report of three cases. Dis. Esophagus 2011, 24, E36–E40. [Google Scholar] [CrossRef]
- Matsumoto, A.; Kanaoka, Y.; Baba, T.; Takizawa, R.; Hara, M.; Maeda, K.; Nishikawa, K.; Suzuki, Y.; Yanaga, K.; Ohki, T. Result of Thoracic Endovascular Aortic Repair for Patients with Esophageal Cancer. World J. Surg. 2018, 42, 1551–1558. [Google Scholar] [CrossRef]
- Mezzetto, L.; Treppiedi, E.; Scorsone, L.; Giacopuzzi, S.; Perandini, S.; Macrì, M.; Veraldi, G.F. Thoracic Aortic Pseudoaneurysm after Esophageal Perforation and Mediastinitis Caused by Accidental Ingestion of a Mutton Bone: A Case Report on Staged Endoscopic and Endovascular Treatments. Ann. Vasc. Surg. 2016, 30, 307.e15–307.e19. [Google Scholar] [CrossRef]
- Omran, S.; Ardalani, L.; Beyer, K.; De Bucourt, M.; Gombert, A.; Buerger, M.; Frese, J.P.B.; Greiner, A. Management of Tumor- and Nontumor-related Aorto-esophageal and Aorto-bronchial Fistulas. Ann. Vasc. Surg. 2021, 72, 419–429. [Google Scholar] [CrossRef]
- Parikh, M.P.; Sherid, M.; Panginikkod, S.; Rawal, H.A.; Gopalakrishnan, V. Radiation therapy-induced aortoesophageal fistula: A case report and review of literature. Gastroenterol. Rep. 2014, 4, 165–167. [Google Scholar] [CrossRef] [Green Version]
- Watanabe, M.; Nakajima, M.; Nishikawa, K.; Kato, H.; Matsubara, H. Thoracic endovascular aortic repair for esophageal cancer invading the thoracic aorta: A questionnaire survey study. Esophagus 2020, 17, 74–80. [Google Scholar] [CrossRef]
- Chen, K.-C.; Wu, I.-H.; Chang, C.-Y.; Huang, P.-M.; Lin, M.-W.; Lee, J.-M. ASO Author Reflections: The Evolution of Treatment for Advanced Esophageal Cancer Invading the Aorta: The Impact of thoracic Endovascular Aortic Repair (TEVAR) on Clinical Outcome. Ann. Surg. Oncol. 2021, 28, 8385–8386. [Google Scholar] [CrossRef]
- Mezzetto, L.; Scorsone, L.; De Pasqual, C.A.; Weindelmayer, J.; Giacopuzzi, S.; de Manzoni, G.; Veraldi, G.F. Preliminary Experience with Prophylactic Thoracic Endovascular Aortic Repair in Patients Affected by Advanced Esophageal Cancer. Ann. Vasc. Surg. 2019, 61, 142–147. [Google Scholar] [CrossRef]
- Lo, C.; Galvin, S.D.; Barnett, S.; Seevanayagam, S. Endovascular repair of iatrogenic aortic rupture. J. Card. Surg. 2013, 28, 561–563. [Google Scholar] [CrossRef]
- Dindo, D.; Demartines, N.; Clavien, P.A. Classification of surgical complications: A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann. Surg. 2004, 240, 205–213. [Google Scholar] [CrossRef] [PubMed]
- Belkin, N.; Jackson, B.M.; Foley, P.J.; Scott, M.; Kalapatapu, V.; Golden, M.A.; Fairman, R.M.; Kelz, R.R.; Wang, G.J. Length of Stay after Thoracic Endovascular Aortic Repair Depends on Indication and Acuity. Ann. Vasc. Surg. 2018, 55, 157–165. [Google Scholar] [CrossRef]
- Hellgren, T.; Beck, A.W.; Behrendt, C.A.; Becker, D.; Beiles, B.; Boyle, J.R.; Jormalainen, M.; Koncar, I.; Espada, C.L.; Setacci, C.; et al. Thoracic endovascular aortic repair practice in 13 countries: A report from VASCUNET and the International Consortium of Vascular Registries. Ann. Surg. 2020, 276, e598–e604. [Google Scholar] [CrossRef] [PubMed]
- Von Allmen, R.S.; Anjum, A.; Powell, J.T. Outcomes after endovascular or open repair for degenerative descending thoracic aortic aneurysm using linked hospital data. J. Br. Surg. 2014, 101, 1244–1251. [Google Scholar] [CrossRef] [PubMed]
- Bischoff, M.S.; Ante, M.; Meisenbacher, K.; Böckler, D. Outcome of thoracic endovascular aortic repair in patients with thoracic and thoracoabdominal aortic aneurysms. J. Vasc. Surg. 2016, 63, 1170–1181.e1. [Google Scholar] [CrossRef] [Green Version]
- Alarhayem, A.Q.; Rasmussen, T.E.; Farivar, B.; Lim, S.; Braverman, M.; Hardy, D.; Jenkins, D.J.; Eastridge, B.J.; Cestero, R.F. Timing of Repair of Blunt Thoracic Aortic Injuries in the TEVAR era. J. Vasc. Surg. 2021, 73, 896–902. [Google Scholar] [CrossRef] [PubMed]
- Czerny, M.; Eggebrecht, H.; Sodeck, G.; Weigang, E.; Livi, U.; Verzini, F. New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fi stulation after thoracic endovascular aortic repair: The European Registry of Endovascular Aortic Repair Complications. Eur. J. Cardio-Thorac. Surg. 2014, 45, 452–457. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Canaud, L.; Ozdemir, B.A.; Bee, W.W.; Bahia, S.; Holt, P.; Thompson, M. Thoracic endovascular aortic repair in management of aortoesophageal fistulas. J. Vasc. Surg. 2014, 59, 248–254. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Jonker, F.H.; Schlösser, F.J.; Moll, F.L.; Van Herwaarden, J.A.; Indes, J.E.; Verhagen, H.J.; Muhs, B.E. Outcomes of Thoracic Endovascular Aortic Repair for Aortobronchial and Aortoesophageal Fistulas. J. Endovasc. Ther. 2009, 16, 428–440. [Google Scholar] [CrossRef]
- Ju, M.H.; Nooromid, M.J.; Rodriguez, H.E.; Eskandari, M.K. Management of hemothorax after thoracic endovascular aortic repair for ruptured aneurysms. Vascular 2018, 26, 39–46. [Google Scholar] [CrossRef] [PubMed] [Green Version]
Variable | Primary Aortic | Secondary Aortic | p Value | ||||||
---|---|---|---|---|---|---|---|---|---|
Aneurysm (n = 14) | Dissection (n = 4) | PAU (n = 4) | Total (n = 22) | Iatrogenic (n = 2) | Trauma (n = 7) | Aortoesophageal Fistula (n = 3) | Total (n = 12) | ||
Male gender (%) | 64.3 | 75 | 100 | 72.7 | 100 | 71.4 | 100 | 83.3 | 0.486 |
Age (years) mean (SD) | 73.2 (12.3) | 69.75 (13.2) | 66.5 (12.6) | 71.4 | 67 (1.4) | 44.1 (17.5) | 60 (6) | 51.9 | 0.002 |
High blood pressure (%) | 85.7 | 50 | 75 | 77.2 | 50 | 0 | 66.7 | 25 | 0.003 |
DM (%) | 7.1 | 0 | 50 | 13.6 | 0 | 0 | 0 | 0 | 0.18 |
CHD (%) | 28.5 | 25 | 25 | 27.3 | 50 | 0 | 33.3 | 16.7 | 0.486 |
Hyperlipidemia (%) | 21.4 | 0 | 0 | 13.6 | 0 | 0 | 0 | 0 | 0.18 |
Renal insufficiency (%) | 28.6 | 0 | 50 | 27.3 | 0 | 0 | 0 | 0 | 0.046 |
COPD (%) | 21.4 | 25 | 0 | 18.2 | 0 | 0 | 0 | 0 | 0.116 |
Variable | Primary Aortic | Secondary Aortic | p Value | ||||||
---|---|---|---|---|---|---|---|---|---|
Aneurysm (n = 14) | Dissection (n = 4) | PAU (n = 4) | Total (n = 22) | Iatrogenic (n = 2) | Trauma (n = 7) | Aortoesophageal Fistula (n = 3) | Total (n = 12) | ||
Percutaneous (%) | 42.85 | 25 | 0 | 31.8 | 0 | 43 | 66.7 | 41.7 | 0.566 |
Hospital stays (days) Median (SD) | 14 (10.8) | 15.5 (3.5) | 18 (13.9) | 14.5 (10.1) | 111.5 (153.4) | 5 (8.7) | 96 (33.55) | 8 (72.7) | 0.746 |
Local anesthesia (%) | 14.3 | 75 | 50 | 31.8 | 0 | 28.6 | 33.3 | 25 | 0.677 |
Hemoglobin level preoperative (mmol/L) Mean (SD) | 6.5 (1.3) | 6.98 (0.27) | 6.65 (1.12) | 6.62 (1.1) | 6.7 (1.4) | 6.47 (1.45) | 5.867 (1.8) | 6.36 (1.1) | 0.942 |
Hemoglobin level postoperative (mmol/L) Mean (SD) | 5.99 (0.98) | 5.88 (0.70) | 6.3 (1.11) | 6.01 (0.93) | 5.65 (0.071) | 6.014 (1.232) | 5.9 (1.71) | 5.93 (1.12) | 0.9 |
Creatinine level preoperative (µmol/L) Mean (SD) | 80.43 (32.2) | 85.25 (36.6) | 75.75 (7.1) | 80.46 (29.1) | 59.5 (28.99) | 95 (46.4) | 107 (46.5) | 92.1 (43.6) | 0.528 |
Creatinine level postoperative (µmol/L) Mean (SD) | 87.7 (35.9) | 76.5 (26.4) | 83 (11.5) | 84.8 (30.5) | 44.5 (20.5) | 97.86 (44.39) | 130.68 (44.8) | 97.2 (47.8) | 0.614 |
Lactate level preoperative (mmol/L) Mean (SD) | 1.54 (1.38) | 2.25 (2.13) | 0.775 (0.15) | 1.53 (1.429) | 1.35 (0.21) | 5.6 (6.16) | 6.833 (6.145) | 5.2 (5.57) | 0.029 |
Lactate level postoperative (mmol/L) Mean (SD) | 1.69 (1.6) | 1.78 (1.38) | 0.73 (0.34) | 1.53 (1.43) | 1.15 (0.35) | 3.96 (4.89) | 6.233 (5.67) | 4.1 (4.7) | 0.233 |
Simultaneous surgery (%) | 21.4 | 50 | 0 | 22.7 | 0 | 28.6 | 33.3 | 25 | 0.881 |
In-Hospital mortality (%) | 35.7 | 25 | 0 | 27.3 | 0 | 28.6 | 66.7 | 33.3 | 0.711 |
Dindo-Clavien ≥ 3 (%) | 42.9 | 25 | 25 | 36.4 | 0 | 28.6 | 66.7 | 33.3 | 0.86 |
Surgery duration (min) | 102.6 (84.3) | 118.75 (86.5) | 42.5 (12.1) | 94.6 (78.5) | 109.5 (96.9) | 58 (26.4) | 87.3 (63.9) | 73.9 (49.2) | 0.493 |
Mortality | Yes (n = 10) | No (n = 24) | p Value |
---|---|---|---|
Etiology (non-aortic) (%) | 40 | 33.3 | 0.721 |
Male gender (%) | 70 | 79.2 | 0.58 |
Age (years) (Mean SD) | 64.4 (19.7) | 64.5 (15.5) | 0.98 |
High blood pressure (%) | 50 | 62.5 | 0.515 |
DM (%) | 0 | 12.5 | 0.255 |
CHD (%) | 10 | 29.2 | 0.243 |
Hyperlipidemia (%) | 10 | 8.3 | 0.881 |
Renal insufficiency (%) | 16.7 | 20 | 0.823 |
COPD (%) | 10 | 12.5 | 0.843 |
Percutaneous (%) | 30 | 37.5 | 0.688 |
Hemoglobin level preoperative (mmol/L) (Mean SD) | 5.5 (1.09) | 6.95 (0.991) | <0.001 |
Hemoglobin level postoperative (mmol/L) (Mean SD) | 5.68 (1.91) | 6.121 (0.911) | 0.249 |
Hemoglobin level difference (preoperative–postoperative) (mmol/L) (Mean SD) | −0.18 (1.072) | 0.833 (1.14) | 0.022 |
Creatinine level preoperative (µmol/L) (Mean SD) | 105 (39.9) | 76 (29.1) | 0.024 |
Creatinine level postoperative (µmol/L) (Mean SD) | 114.4 (43.4) | 76 (29.1) | 0.009 |
Creatinine level difference (preoperative–postoperative) (mmol/L) (Mean SD) | −9.4 (28.336) | −2.625 (17.093) | 0.395 |
Lactate level preoperative (mmol/L) (Mean SD) | 6.38 (5.45) | 1.35 (1.21) | <0.001 |
Lactate level postoperative (mmol/L) (Mean SD) | 5.78 (4.297) | 1.025 (0.481) | <0.001 |
Lactate level difference (preoperative–postoperative) (mmol/L) (Mean SD) | 0.321 (1.101) | −9.4 (28.336) | 0.625 |
Simultaneous surgery (%) | 40 | 16.7 | 0.153 |
Surgery duration (min) (Mean SD) | 111.8 (94.7) | 77.1 (55.2) | 0.189 |
Morbidity (Dindo–Clavien > 3) (%) | 100 | 8.3 | <0.001 |
Local anesthesia (%) | 30 | 29 | 0.963 |
Hospital stay (days) (Mean SD) | 27.7 (36.6) | 29.5 (50.1) | 0.917 |
Morbidity (Dindo–Clavien ≥ 3) | Yes (n = 12) | No (n = 22) | pValue |
Etiology (non-aortic) (%) | 33.3 | 36.4 | 0.865 |
Male gender (%) | 75 | 77.3 | 0.886 |
Age (years) (Mean SD) | 66.8 (18.8) | 63.2 (15.5) | 0.552 |
High blood pressure (%) | 58.3 | 59.1 | 0.967 |
DM (%) | 0 | 13.6 | 0.191 |
CHD (%) | 16.7 | 27.3 | 0.501 |
Hyperlipidemia (%) | 16.7 | 4.5 | 0.247 |
Renal insufficiency (%) | 25 | 13.6 | 0.422 |
COPD (%) | 16.7 | 9.1 | 0.527 |
Percutaneous (%) | 25 | 40.9 | 0.369 |
Hemoglobin level preoperative (mmol/L) (Mean SD) | 5.69 (1.21) | 6.98 (0.96) | 0.002 |
Hemoglobin level postoperative (mmol/L) (Mean SD) | 5.7 (1.1) | 6.15 (0.94) | 0.217 |
Hemoglobin level difference (preoperative–postoperative) (mmol/L) (Mean SD) | −0.008 (1.263) | 0.832 (1.079) | 0.032 |
Creatinine level preoperative (µmol/L) (Mean SD) | 99.75 (38.2) | 76.3 (30.5) | 0.058 |
Creatinine level postoperative (µmol/L) (Mean SD) | 107.25 (42.7) | 79.3 (30.7) | 0.035 |
Creatinine level difference (preoperative–postoperative) (mmol/L) (Mean SD) | −7.5 (26.012) | −3.045 (17.826) | 0.529 |
Lactate level preoperative (mmol/L) (Mean SD) | 5.48 (5.445) | 1.38 (1.25) | 0.002 |
Lactate level postoperative (mmol/L) (Mean SD) | 4.98 (4.3) | 1.03 (0.495) | <0.001 |
Lactate level difference (preoperative–postoperative) (mmol/L) (Mean SD) | 0.492 (2.026) | 0.355 (1.145) | 0.684 |
Simultaneous surgery (%) | 41.7 | 13.6 | 0.069 |
Surgery duration (min) (Mean SD) | 116.5 (95.4) | 71.4 (45.6) | 0.07 |
Mortality (%) | 83 | 0 | <0.001 |
Local Anesthesia (%) | 33.3 | 27.3 | 0.721 |
Hospital stay (days) (Mean SD) | 28.18 (33.2) | 29.46 (52.39) | 0.939 |
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Rebelo, A.; Partsakhashvili, J.; Ronellenfitsch, U.; John, E.; Kleeff, J.; Ukkat, J. Single-Center Retrospective Subgroup Analysis of “Primary Aortic” (Aneurysm, Aortic Dissection, PAU) and “Secondary Aortic” (Iatrogenic, Trauma, Aortoesophageal Fistula) Indications for Emergency TEVAR. J. Clin. Med. 2023, 12, 4037. https://doi.org/10.3390/jcm12124037
Rebelo A, Partsakhashvili J, Ronellenfitsch U, John E, Kleeff J, Ukkat J. Single-Center Retrospective Subgroup Analysis of “Primary Aortic” (Aneurysm, Aortic Dissection, PAU) and “Secondary Aortic” (Iatrogenic, Trauma, Aortoesophageal Fistula) Indications for Emergency TEVAR. Journal of Clinical Medicine. 2023; 12(12):4037. https://doi.org/10.3390/jcm12124037
Chicago/Turabian StyleRebelo, Artur, Jumber Partsakhashvili, Ulrich Ronellenfitsch, Endres John, Jörg Kleeff, and Jörg Ukkat. 2023. "Single-Center Retrospective Subgroup Analysis of “Primary Aortic” (Aneurysm, Aortic Dissection, PAU) and “Secondary Aortic” (Iatrogenic, Trauma, Aortoesophageal Fistula) Indications for Emergency TEVAR" Journal of Clinical Medicine 12, no. 12: 4037. https://doi.org/10.3390/jcm12124037