Effect of the Pandemic Outbreak on ICU-Associated Infections and Antibiotic Prescription Trends in Non-COVID19 Acute Respiratory Failure Patients
, Alessandra Quaranta 3, Valentina Cricca 3, Elisabetta Marangoni 3, Riccardo La Rosa 1, Sara Bertacchini 3, Alessandra Bellonzi 3, Riccardo Ragazzi 1,3, Carlo Alberto Volta 1,3, Savino Spadaro 1,3 and Gaetano Scaramuzzo 1,3,*Round 1
Reviewer 1 Report
Thank you for giving me the opportunity to review this paper. It is an interesting research paper. Overall, the research is well designed and clear. However, I have some comments for the authors to address.
general comments: Some sentences are long and difficult to follow. I recommend the authors to break them into smaller sentences. Also there are few typos in the manuscript (e.g., the first 3 wave of the pandemic).
Specific comments.
1- line 48-50 (same considerations......... (NHSN)). This seems out of place, please consider revising or taking out this line.
2- please use "wave" instead of "part" for this line "especially in the first part of the pandemic"
3- Please define what Simplified Acute Physiology Score II is for the readers.
4- categorical variables are reported as number...... please change number to frequency.
5- I think you are missing values in table 4 for "smoke"
6- in table 2 and 3, does "Nr" means number? if yes, please be consistent.
7- I believe that you need to mention that single-centered is one of your limitations.
Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
A professionally written article that sheds light on an interesting issue.
One issue that might be interested is to elaborate a bit more on the length of steroids administration (shorter in the PI group).
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
