Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder
Abstract
:1. Introduction
2. Clinical Correlations
3. Polymorphism
3.1. SNP rs6265
3.1.1. SNP rs6265 and Depression
3.1.2. SNP rs6265 and Schizophrenia
3.1.3. SNP rs6265 and Bipolar Disorder
3.2. SNP rs11030101
3.3. SNP rs11030104
3.4. SNP rs10835210
3.5. SNP rs2049046
3.6. SNP rs61888800
3.7. SNP rs2030324
3.8. SNP rs10501087
3.9. SNP rs12273539
3.10. SNP rs7124442
3.11. SNP rs1519480
3.12. SNP rs11030094
3.13. SNP rs28383487
3.14. SNP rs16917237
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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SNP | Gene: Consequence | Genomic Position | Alleles |
---|---|---|---|
rs6265 | BDNF: Missense Variant | chr11:27658369 (GRCh38.p14) | C > T |
BDNF-AS: Non-Coding Transcript Variant | |||
rs11030101 | BDNF: Intron Variant | chr11:27659197 (GRCh38.p14) | A > G/A > T |
BDNF-AS: Non-Coding Transcript Variant | |||
rs11030104 | BDNF: Intron Variant | chr11:27662970 (GRCh38.p14) | A > G |
BDNF-AS: Intron Variant | |||
rs7124442 | BDNF: 3 Prime UTR Variant | chr11:27655494 (GRCh38.p14) | C > G/C > T |
BDNF-AS: Intron Variant | |||
rs10835210 | BDNF: Intron Variant | chr11:27674363 (GRCh38.p14) | C > A/C > G |
BDNF-AS: Intron Variant | |||
rs12273539 | BDNF: Intron Variant | chr11:27661764 (GRCh38.p14) | C > T |
BDNF-AS: Intron Variant | |||
rs16917237 | BDNF: Intron Variant | chr11:27680836 (GRCh38.p14) | G > T |
BDNF-AS: Intron Variant | |||
rs2049046 | BDNF: Intron Variant | chr11:27702228 (GRCh38.p14) | T > A |
rs61888800 | BDNF: Intron Variant | chr11:27700731 (GRCh38.p14) | G > C/G > T |
rs2030324 | BDNF: Intron Variant | chr11:27705368 (GRCh38.p14) | A > G |
rs28383487 | BDNF: 5 Prime UTR Variant | chr11:27722009 (GRCh38.p14) | G > T |
LOC124902652: 2KB Upstream Variant | |||
rs10501087 | BDNF-AS: Intron Variant | chr11:27648561 (GRCh38.p14) | T > C/T > G |
rs11030094 | BDNF-AS: Intron Variant | chr11:27638228 (GRCh38.p14) | G > A |
rs1519480 | BDNF-AS: Intron Variant | chr11:27654165 (GRCh38.p14) | C > A/C > G/C > T |
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Shkundin, A.; Halaris, A. Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder. J. Pers. Med. 2023, 13, 1395. https://doi.org/10.3390/jpm13091395
Shkundin A, Halaris A. Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder. Journal of Personalized Medicine. 2023; 13(9):1395. https://doi.org/10.3390/jpm13091395
Chicago/Turabian StyleShkundin, Anton, and Angelos Halaris. 2023. "Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder" Journal of Personalized Medicine 13, no. 9: 1395. https://doi.org/10.3390/jpm13091395