1. Introduction
Grain is an important foundation of national security. The scale of grain storage and the function of facilities determine the national grain circulation capacity. There are many occupational hazards that can affect the health of workers in the process of grain storage. Grain contains a large amount of mixed dust, including grain husks, bacteria, pests, microorganisms, and mixed fine sand [
1]. Grain dust is a companion in the whole life cycle of modern grain, from purchase to storage, transportation, and processing. It is produced due to friction, collision, extrusion, crushing, etc. [
2]. The particle size distribution of dust is approximately normal, ranging in size from 0 to 9.6 × 10
5 nm, with a true density within the range of 1.1–1.8 g/m
3 [
3]. During the storage process, grain is constantly tumbling, and the dust particles are continuously separated under the influence of air flow. The instantaneous contact mass concentration can reach up to 1000 mg/m
3, and the time-weighted average allowable concentration is about 40 mg/m
3. Workers are often exposed to inhalable dust of >10 mg/m
3, and higher exposures can be found at the grain in-warehousing and out-warehousing stages [
4].
Dust can cause serious environmental pollution, grain quality decline, mechanical equipment wear, and, more importantly, it also threatens the health of grain warehouse operators. Studies have shown that long-term exposure to high-concentration grain storage dust can easily irritate the respiratory system [
5]. When accumulated after inhalation, it can cause allergic reactions [
6] and cereal fever syndrome [
7]. In severe cases, it may cause respiratory diseases such as pneumoconiosis, hardening of the respiratory organs, and recurrent nocturnal asthma [
8]. Dust can also enter the blood with human cells, which can cause further cardiovascular and cerebrovascular diseases [
9]. Due to its potential hazards, monitoring grain dust, studying its distribution rules, and quantifying the health damage are important steps in effectively recognizing and measuring the health hazards of dust.
Researchers have recently begun to pay more attention to the physical and chemical properties [
10], sources [
11], explosive characteristics [
12,
13,
14], prevention measures [
15], and mycotoxin content [
16,
17] of grain dust. When conducting occupational hazard analysis, the toxicological characteristics [
18], the mechanism of action on the respiratory tract [
19], and the clinical manifestations of diseases [
20] related to grain dust have mostly been analyzed from a medical perspective, and there is a lack of quantitative evaluation of its health damage.
Dust health damage assessment has been carried out with reference to coal mines, construction, atmospheric environment, and other fields using deterministic analysis methods. For example, Behrooz et al. assessed the carcinogenic and non-carcinogenic health risks for three exposure pathways in airborne dust samples (TSP and PM
2.5) in Zabol, Iran during the summer dust period [
21]; Guney et al. characterized contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content and assessed elemental lung bioaccessibility in fine fraction [
22]; Donghua et al. proposed an occupational health hazard risk assessment matrix method to rank the hazards of various risk factors in mining and mineral processing [
23]; Lim et al. investigated the contamination levels and dispersion patterns of heavy metals and assessed the risk of health effects on the residence in the vicinity of the abandoned Songcheon Au-Ag mine, Korea [
24]; Kan et al. calculated the health damage of air particulate pollution based on the epidemiological exposure–response function [
25]; Zhang M. et al. assessed particulate pollution risk and quantified the public health damage caused by air emissions in Beijing in the period 2000–2004 [
26]; Liu E. et al. labeled the indicative metals relating to non-exhaust traffic emissions and assessed anthropogenic sources of metals in TR dusts, combining their spatial pollution patterns, principal component analysis, and Pb isotopic compositions [
27]; Zhang Y. et al. analyzed eight heavy metals (Cr, Ni, Cu, Cd, Pb, Zn, Mn, and Co) in the PM2.5, collected during four different seasons in Taiyuan, a typical coal-burning city in northern China [
28]; Chen X. et al. established a health risk assessment system based on on-site measurements and assessed the health risks for a tunnel machine employee [
29]; Zheng et al. investigated the heavy metal contamination in the street dust due to metal smelting in the industrial district of Huludao city and elucidated the spatial distribution of Hg, Pb, Cd, Zn, and Cu in the street dust [
30]; Tahir et al. described the estimation of particulate matter (cotton dust) with different sizes in small-scale weaving industry (power looms) situated in district Hafizabad, Punjab, Pakistan, and the assessment of health problems of workers associated with these pollutants [
31]; Zazouli et al. investigated the mineralogy, micro-morphology, chemical characteristics, and oxidation toxicity of respirable dusts generated in underground coal mines and assessed the health risk by EPA’s health risk model [
32]; and Li X et al. introduced the disability-adjusted life year (DALY) model for damage to human health caused by construction dust, to evaluate the environmental impact during the construction process [
33]. Scholars have studied the health risks of dust from the perspective of components of heavy metals and the construction of a risk assessment model, which have laid the foundation for the risk assessment of grain dust. However, there are few studies evaluating the health damage caused by grain dust, despite the importance of grain storage and transport in the process of ensuring grain security. This study is particularly timely, as the circulation of grain in the market is accelerating, so a large amount of grain dust will be generated in specific areas. Inhalation is considered to be the main route of human exposure to grain dust [
34]. The present research is of great significance for understanding the health status of grain warehouse personnel, as there is a need to evaluate the hazard to human health posed by the grain dust present in granaries.
Current research on quantitative occupational health risk assessment in other industries has yielded instructive conclusions and methods [
35,
36,
37]. In fact, risk assessment methods include deterministic analysis methods and uncertainty analysis methods. The accuracy of the conclusions drawn from the deterministic method cannot be guaranteed, as the method calculates the health risk through the most probable and maximum value of human exposure parameters and pollutant content [
38], resulting in large or small results [
39]. However, the problem of uncertainty is inherent in health risk assessment and runs through the whole process [
40,
41]. The operation area, time, and season of the grain warehouse make the dust concentration uncertain. The uncertainty of human exposure parameters, temperature and humidity changes, and meteorological conditions in the relatively open working environment of the grain warehouse also causes uncertainty in the evaluation results. Hence, this study used the uncertainty analysis method (i.e., the Monte Carlo method) to evaluate the health damage caused by grain dust in warehouses.
To address the uncertainty in grain dust health hazard assessment, a total of 616 samples were collected in China in Hefei (Anhui), Shenzhen (Guangdong), Chengdu (Sichuan), Changchun (Jilin), and Shunyi (Beijing). Additionally, a risk assessment model for the health damage caused by grain dust through inhalation was proposed, considering the dust concentration and the uncertainty of the exposure parameters, and grouping them according to different operation processes and grain varieties (i.e., maize, rice, and wheat) based on the current health risk evaluation system of the United States Environmental Protection Agency (USEPA). The Monte Carlo simulation and Crystal Ball 11.1 software were used to quantify the health damage and to analyze the impact of various parameters on health risks. The results provide guidance for occupational health risk management in the grain storage industry. To our knowledge, this is one of the first studies to analyze and evaluate the hazards of grain dust to human health through inhalation by the uncertainty analysis method.
4. Conclusions
The dust concentration, levels, and sources, as well as the resulting health damage created during transportation and storage at Chinese grain storage companies were thoroughly investigated in this study. First, 616 dust samples from different stages (out-warehousing, in-warehousing, and transporting) and types of grain (maize, wheat, and rice) in five cities were collected and analyzed using the filter membrane method and a laser particle size analyzer. A risk assessment model for grain dust inhalation was established based on the current USEPA health risk assessment system. The health damage of grain dust was quantified by Monte Carlo simulation and Crystal Ball 11.1 software. The DALY was chosen as the final indicator to quantify the health damage. The results showed that the concentration of grain dust ranged from 25 to 70 mg/m3, and the distribution was normal. The proportion of dust with a particle size less than 10 μm exceeded 10%, which could seriously threaten workers’ respiratory system. Based on grain type, the dust risk in each stage followed a lognormal distribution, and the health risk of maize at each stage was the largest, at 1.42 × 10−6 ± 9.14 × 1 0−7 during out-warehousing, 1.24 × 10−6 ± 8.27 × 1 0−7 during in-warehousing, and 2.34 × 10−6 ± 1.32 × 10−6 during transport. By stage, the health risk of grain dust can be ranked as follows: the transporting stage > the out-warehousing stage > the in-warehousing stage. The sensitivity analysis indicated that average time (AT), exposure duration (ED), inhalation rate (IR), and dust concentration (C) made the greatest contribution to dust health risk, while AT and body weight exhibited a negative sensitivity. The DALY caused by dust during grain storage was between 0.1 and 3.3 years. The DALY of maize was the largest during the in-warehousing stage, with an average value of 1.01 years, while the DALY of rice and wheat were the largest during the transporting stage, with an average value of 0.89 and 0.83 years, respectively.
The results of this study provide a new perspective for grain storage dust damage assessment. The dust concentration, particle size, and distribution characteristics of three kinds of grain at three storage stages were described, and preventive measures were proposed. The maximum, minimum, standard deviation, and quantile of risk were obtained by the probability risk assessment method to guarantee the comprehensiveness of the results. Furthermore, the DALY can directly reflect the damage of dust to human beings. To resolve the uncertainty of the results caused by various factors and the limitations of the evaluation method, future studies could increase the data sampling and investigation of exposure parameters, and assess the risk for the dermal contact and ingestion pathways to ensure the results are more accurate.