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Article
Peer-Review Record

Identification of New Genes and Genetic Variant Loci Associated with Breast Muscle Development in the Mini-Cobb F2 Chicken Population Using a Genome-Wide Association Study

Genes 2022, 13(11), 2153; https://doi.org/10.3390/genes13112153
by Yang He 1,†, Hongmei Shi 1,†, Zijian Li 1, Jiajia Kang 1, Mengyuan Li 1, Mengqian Liu 1, Yong Liu 1, Jinbo Zhao 1, Tengfei Dou 1, Junjing Jia 1, Yong Duan 2, Kun Wang 1 and Changrong Ge 1,*
Reviewer 2: Anonymous
Genes 2022, 13(11), 2153; https://doi.org/10.3390/genes13112153
Submission received: 1 November 2022 / Revised: 14 November 2022 / Accepted: 17 November 2022 / Published: 18 November 2022
(This article belongs to the Special Issue Advances in Poultry Genetics and Breeding)

Round 1

Reviewer 1 Report

In general, the document is well-written and of good quality. It is advisable that the authors improve or justify some details of the methodology. The conclusion should be improved

Author Response

"Please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

The aim of this study was to explore the potential genetic mechanisms of breast muscle development in a F2 population constructed by reciprocal crosses between a fast-growing broiler hybrid (Cobb500) and a slow-growing native breed (Daweishan mini). The manuscript is well written but I would have a few small suggestions. Why was Spearman's correlation coefficient used, when it is used in the case of rank correlation. I think it would be more appropriate in this case to use the Pearson correlation coefficient. Line 199-200_explain in what sense the population is clearly differentiated. Additionally clarify why the variability of phenotypic values for breast muscle weight and sternum weight is highest.

Author Response

Please see the attachment

Author Response File: Author Response.docx

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