Role of Aldynoglia Cells in Neuroinflammatory and Neuroimmune Responses after Spinal Cord Injury
Abstract
:1. Introduction
2. Characteristics of Aldynoglia Cells in Brain
3. Morphological and Functional Characteristics of Tanycytes and Pituicytes
4. Olfactory Ensheathing Cells
5. Müller Cells
6. Bergmann Glial Cells
7. Pineal Gland Cells
8. Aldynoglia Cells in Spinal Cord
9. Secondary Cell Death in Spinal Cord after Injury
- Acute phase, spanning 0 to 2 days after the injury,
- Subacute phase, 3 days to weeks after the injury,
- Chronic phase, 7 weeks to years after the injury,
10. Innate Immune Response in Spinal Cord Injury
11. The Adaptive Immune Response after SCI
12. Phagocytic Immune Cells in Acute and Sub-Acute Phases of SCI
13. The Transition from M1 to M2 Phenotype for Microglia/Macrophage in Sub-Acute and Chronic Phases after SCI
14. M1 Macrophage/Microglia Promotes Proliferation of Aldynoglia Cells in Sub-Acute Phase after SCI
15. M2 Macrophage/Microglia Induce Aldynoglial Cell Differentiation in Chronic Phase of SCI
16. Chronic Phase of Traumatic Spinal Cord Injury: The Activity of Aldynoglia
17. Effect of Aldynoglia Cells on Regeneration after SCI
18. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Location In Brain | Cellular Type | Markers | Bibliography |
---|---|---|---|
Subventricular zone, third ventricle | Tanycytes | GFAP, p75 NGFR, vimentin, S100β | [9,10] |
Hypothalamus | Pituicytes | ||
Olfactory Bulb | Ensheathing olfactory cells | GFAP, p75 NGFR, vimentin, S100β, ERα | [11] |
Retina | Müller glia cells | GFAP, p75 NGFR, vimentin. | [12,13] |
Ventricular area of the cerebellum | Bergmann glia cells | GFAP, p75 NGFR, vimentin, S100β, S0X1, SOX2, SOX9. | [14] |
Pineal gland | Pinealocytes | GFAP, vimentin. | [15,16,17] |
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Buzoianu-Anguiano, V.; Torres-Llacsa, M.; Doncel-Pérez, E. Role of Aldynoglia Cells in Neuroinflammatory and Neuroimmune Responses after Spinal Cord Injury. Cells 2021, 10, 2783. https://doi.org/10.3390/cells10102783
Buzoianu-Anguiano V, Torres-Llacsa M, Doncel-Pérez E. Role of Aldynoglia Cells in Neuroinflammatory and Neuroimmune Responses after Spinal Cord Injury. Cells. 2021; 10(10):2783. https://doi.org/10.3390/cells10102783
Chicago/Turabian StyleBuzoianu-Anguiano, Vinnitsa, Mabel Torres-Llacsa, and Ernesto Doncel-Pérez. 2021. "Role of Aldynoglia Cells in Neuroinflammatory and Neuroimmune Responses after Spinal Cord Injury" Cells 10, no. 10: 2783. https://doi.org/10.3390/cells10102783