Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB)
Round 1
Reviewer 1 Report
I read the manuscript, "Anemia is a strong predictor of wasting, disease severity and progression of clinical tuberculosis (TB)," with great interest. I believe this is a scientifically and well-written manuscript on the relation between anemia and TB disease manifestations and outcomes. I have a few minor comments:
1. Introduction, lines 79-81: there is no need to present the main result in the introduction
2. I am having my doubts about the methodology, I think it is better if the authors make it clear that there is no effect of vitamin D deficiency or interventions regarding vitamin D have a cofounding effect on the results of this study. I know it is unlikely, and I can see the clear results from the analysis, but I still find it useful to be clearly mentioned in the results/discussion.
3. I believe SD would be a better fit than SEM for the presentation of the results
Author Response
Please, see the attachment below.
Author Response File: Author Response.docx
Reviewer 2 Report
From my point of view, the article is exciting. It respects the scientific rigor of presenting the results of well-conducted research. It also has a clinical impact by identifying risk factors for a severe form of tuberculosis. The importance of low Hb and a low BMI as unfavorable prognostic factors for the disease is emphasized. Prevention of risk factors can lead to a decrease in TB morbidity and mortality.
Author Response
Please, see the attachment below.
Author Response File: Author Response.docx