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Pediatric Reports
Volume 4
Issue 1
10.4081/pr.2012.e14
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Case Report

Urinary Sludge Caused by Ceftriaxone in a Young Boy

by
Takahisa Kimata
1,
Kauznari Kaneko
1,*,
Masaya Takahashi
1,
Sohsaku Yamanouchi
1,
Shoji Tsuji
1 and
Minoru Kino
2
1
Department of Pediatrics, Kansai Medical University
2
Nakano Children’s Hospital, Osaka, Japan
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2012, 4(1), e14; https://doi.org/10.4081/pr.2012.e14
Submission received: 27 September 2011 / Revised: 29 December 2011 / Accepted: 29 December 2011 / Published: 26 March 2012

Abstract

It is known that ceftriaxone administration is associated with biliary pseudolithiasis, although the development of urolithiasis has been rarely reported. We encountered a young male with bacterial meningitis complicated by urinary precipitates composed of ceftriaxonecalcium salt which is confirmed by high-performance liquid chromatography. This patient suggested that ceftriaxone significantly increased urinary excretion of calcium, which may be linked to ceftriaxone-related urolithiasis or sludge. It is therefore worthwhile to monitor the levels of urinary calcium to creatinine ratio in patients on ceftriaxone, as they may be at greater risk for developing large stones and renal damage.
Keywords: Ceftriaxone; urolithiasis; urinary calcium; urinary sludge; hypercalciuria Ceftriaxone; urolithiasis; urinary calcium; urinary sludge; hypercalciuria

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MDPI and ACS Style

Kimata, T.; Kaneko, K.; Takahashi, M.; Yamanouchi, S.; Tsuji, S.; Kino, M. Urinary Sludge Caused by Ceftriaxone in a Young Boy. Pediatr. Rep. 2012, 4, e14. https://doi.org/10.4081/pr.2012.e14

AMA Style

Kimata T, Kaneko K, Takahashi M, Yamanouchi S, Tsuji S, Kino M. Urinary Sludge Caused by Ceftriaxone in a Young Boy. Pediatric Reports. 2012; 4(1):e14. https://doi.org/10.4081/pr.2012.e14

Chicago/Turabian Style

Kimata, Takahisa, Kauznari Kaneko, Masaya Takahashi, Sohsaku Yamanouchi, Shoji Tsuji, and Minoru Kino. 2012. "Urinary Sludge Caused by Ceftriaxone in a Young Boy" Pediatric Reports 4, no. 1: e14. https://doi.org/10.4081/pr.2012.e14

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