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Infectious Disease Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.

Infect. Dis. Rep., Volume 6, Issue 3 (August 2014) – 4 articles

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595 KiB  
Case Report
Intra-pleural colistin methanesulfonate therapy for pleural infection caused by carbapenem-resistant Acinetobacter baumannii: a successful case report
by Muhammad Asim Rana, Basheer Abd El Rahaman, Ahmed Fouad Mady, Mohammed Al Odat, Abdurehman Al Harthy, Omar El Sayed Ramadan, Shehzad Ahmad Mumtaz and Ali S. Omrani
Infect. Dis. Rep. 2014, 6(3), 5413; https://doi.org/10.4081/idr.2014.5413 - 23 Sep 2014
Cited by 7 | Viewed by 540
Abstract
Infections caused by carbapenem-resistant, Gram-negative bacteria are an increasing clinical challenge, since the antimicrobial treatment options are often limited to colistin methanesulfonate. No data are available regarding the pharmacokinetics of colistin in pleural fluid. We report the case of a 92-year old man [...] Read more.
Infections caused by carbapenem-resistant, Gram-negative bacteria are an increasing clinical challenge, since the antimicrobial treatment options are often limited to colistin methanesulfonate. No data are available regarding the pharmacokinetics of colistin in pleural fluid. We report the case of a 92-year old man with ventilator-associated pneumonia and pleurisy caused by Acinetobacter baumannii and Escherichia coli, which were both multidrug-resistant. After an unsuccessful treatment with intravenous colistin methanesulfonate and imipenem-cilastatin, the addition of intra-pleural colistin methanesulfonate to the intravenous treatment led to a prompt clinical, radiological and microbiological resolution. This is the first report of a successful use of intra-pleural colistin in the literature. The intra-pleural colistin therapy should be considered in selected cases of pleurisy caused by multi-resistant Gram-negative bacteria. Full article
1043 KiB  
Case Report
Massive alimentary tract bleeding due to cytomegalovirus infection in an elderly patient
by Bora Koc, Huseyin Yuce Bircan, Semsi Altaner, Ozlem Cinar, Umit Ozcelik, Alpaslan Yavuz and Ozgur Kemik
Infect. Dis. Rep. 2014, 6(3), 5512; https://doi.org/10.4081/idr.2014.5512 - 22 Sep 2014
Cited by 5 | Viewed by 399
Abstract
In recent years, cytomegalovirus (CMV) has been recognized as an important common pathogen in immunocompromized patients. This is due to the increasing number of immunosuppressive medications, intensive cancer chemotherapy use, recurrent transplantations, progressively aging population, and the higher number of human immunodeficiency virus [...] Read more.
In recent years, cytomegalovirus (CMV) has been recognized as an important common pathogen in immunocompromized patients. This is due to the increasing number of immunosuppressive medications, intensive cancer chemotherapy use, recurrent transplantations, progressively aging population, and the higher number of human immunodeficiency virus infections. Cytomegalovirus infection especially interests the gastrointestinal tract, anywhere, from the mouth to the anus. Namely, the most commonly affected area is the colon, followed by duodenum, stomach, esophagus and small intestine. The most frequent manifestations of CMV colitis are: diarrhea, fever, gastrointestinal bleeding and abdominal pain. We report here the case of an 82-year-old woman, who was treated for non-Hodgkin lymphoma; she was admitted to the emergency department for abdominal pain and diffuse arthralgia, following massive upper- and lower- gastrointestinal bleeding, due to duodenal and colonic ulcers related to CMV infection. Full article
627 KiB  
Case Report
Disseminated cutaneous herpes zoster in an immunocompetent elderly patient
by Eric Gomez and Ivan Chernev
Infect. Dis. Rep. 2014, 6(3), 5513; https://doi.org/10.4081/idr.2014.5513 - 26 Aug 2014
Cited by 21 | Viewed by 660
Abstract
Herpes zoster is a clinical syndrome which usually presents with a localized, vesicular rash in a dermatomal distribution. Cutaneous dissemination rarely occurs in immunocompetent patients, therefore little is known about the baseline demographic, clinical characteristics, management and outcome of these patients. Herein, we [...] Read more.
Herpes zoster is a clinical syndrome which usually presents with a localized, vesicular rash in a dermatomal distribution. Cutaneous dissemination rarely occurs in immunocompetent patients, therefore little is known about the baseline demographic, clinical characteristics, management and outcome of these patients. Herein, we report a case of disseminated cutaneous herpes zoster in an immunocompetent patient along with a review and analysis of 28 cases previously reported in the literature. Full article
554 KiB  
Case Report
Lactobacillus endocarditis with prosthetic material: a case report on non-surgical management with corresponding literature review
by Mena Botros and Deepa Mukundan
Infect. Dis. Rep. 2014, 6(3), 5497; https://doi.org/10.4081/idr.2014.5497 - 13 Aug 2014
Cited by 9 | Viewed by 387
Abstract
Lactobacilli are rod shaped gram positive bacteria that naturally colonize the human gastrointestinal and genitourinary tracts and occasionally cause disease in humans. Lactobacillus infections are found in patients who are immunocompromized or have severe comorbidities. We report Lactobacillus endocarditis in a 17-year-old adolescent [...] Read more.
Lactobacilli are rod shaped gram positive bacteria that naturally colonize the human gastrointestinal and genitourinary tracts and occasionally cause disease in humans. Lactobacillus infections are found in patients who are immunocompromized or have severe comorbidities. We report Lactobacillus endocarditis in a 17-year-old adolescent girl with cardiac prosthetic material following surgical correction for complex cyanotic congenital heart disease. Accurate identification of the organism can be delayed. Despite in vivo susceptibility to vancomycin, our patient clinically failed vancomycin therapy but ultimately responded to a six-week course of penicillin, in addition to a 4-week course of clindamycin and gentamicin. She recovered without the need for surgical intervention and has been symptom free for one year. Upon review of the literature, we found that Lactobacillus endocarditis has not been reported in a pediatric patient with complex cyanotic congenital heart disease. Full article
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