Melatonin Action on the Activity of Phagocytes from the Colostrum of Obese Women
Abstract
:1. Introduction
2. Materials and Methods
2.1. Subject
2.2. Colostrum Sampling and the Separation of Colostral Cells
2.3. Determination of Hormone
2.4. Treatment of Colostral Phagocytes with Melatonin
2.5. Phagocytosis ASSAY
2.6. Analysis of Reactive Oxygen Species
2.7. Apoptosis Assays
2.8. Intracellular Ca2+Release Determined by Fluorescence
2.9. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Maternal and Child Characteristics | Normal BMI | High BMI |
---|---|---|
Age (years) | 26.7 ±5.5 | 26.6 ±5.7 |
Diabetes or gestational diabetes (%) | 0 0.0% | 0 0.0% |
Pregestational maternal BMI (kg/m2) | 21.7 ±1.9 | 31.3 ±3.9 * |
Delivery BMI (kg/m2) | 26.3 ±2.9 | 35.2 ±3.7 * |
Gestational weight gain(kg) | 11.3 ±3.9 | 9.3 ±3.6 |
Gestational age at delivery (weeks) | 38.9 ±1.1 | 38.8 ±1.0 |
Infant sex—male (%) | 26 52.0% | 28 56.0% |
Birth weight (g) | 3324 ±428 | 3346 ±495 |
Birth height (cm) | 46.7 ±3.5 | 47.4 ±3.3 |
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Morais, T.C.; Honorio-França, A.C.; Fujimori, M.; de Quental, O.B.; Pessoa, R.S.; França, E.L.; de Abreu, L.C. Melatonin Action on the Activity of Phagocytes from the Colostrum of Obese Women. Medicina 2019, 55, 625. https://doi.org/10.3390/medicina55100625
Morais TC, Honorio-França AC, Fujimori M, de Quental OB, Pessoa RS, França EL, de Abreu LC. Melatonin Action on the Activity of Phagocytes from the Colostrum of Obese Women. Medicina. 2019; 55(10):625. https://doi.org/10.3390/medicina55100625
Chicago/Turabian StyleMorais, Tassiane C., Adenilda C. Honorio-França, Mahmi Fujimori, Ocilma B. de Quental, Rafael S. Pessoa, Eduardo L. França, and Luiz C. de Abreu. 2019. "Melatonin Action on the Activity of Phagocytes from the Colostrum of Obese Women" Medicina 55, no. 10: 625. https://doi.org/10.3390/medicina55100625