Associations of the quality of life and psychoemotional state with sociodemographic factors in patients with psoriasis

Objective: The aim of this study was to evaluate the interrelationships between the quality of life and psycho-emotional, demographic, and clinical factors in patients with psoriasis.
Materials and methods: The study included 18-year-old or older patients with psoriasis recruited from the university hospital (n = 385). Their sociodemographic data, Psoriasis Area and Severity Index score and disease duration were assessed. The quality of life was evaluated by using the Dermatology Life Quality Index. Depression and anxiety were assessed using the Hospital Anxiety and Depression scale.
Results: A severe change in the quality of life (DLQI ≥ 10 points) was found by 1.8 times more commonly in females, by 2.7 times more commonly in patients with moderate and severe psoriasis (PASI ≤ 10) than in those with a mild psoriasis (PASI ≤ 10), and by about 2 times more commonly in patients with nail psoriasis than in those without, as well as in patients with psoriasis-related anxiety or depression than in subjects without those symptoms. Anxiety and depression were observed in 37.4% and 23.4% of the patients, respectively. Depression was more frequent in patients older than 55 years than in those <35 years of age. Anxiety was more frequent in females and in the respondents with primary and unfinished secondary education.
Conclusions: One-half of patients with psoriasis, women more often than men, regardless of the severity of the disease, reported a significant change in their quality of life. Patients with psoriasis, especially women and older people (aged more than 55 years), experienced anxiety and symptoms of depression.