Next Article in Journal
Responses of Cariogenic Streptococci to Environmental Stresses
Previous Article in Journal
The Apicoplast: A Review of the Derived Plastid of Apicomplexan Parasites
 
 
Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

The Surface of the Plasmodium falciparum-infected Erythrocyte

by
Joseph D. Smith
1,2 and
Alister G. Craig
3,*
1
Department of Pathology, Colorado State University, Ft. Collins, CO 80523-1671, USA
2
Seattle Biomedical Institute, Four Nickerson Street, Suite 200, Seattle, WA 98109-1651, USA
3
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2005, 7(1), 81-94; https://doi.org/10.21775/cimb.007.081
Submission received: 8 July 2004 / Revised: 8 September 2004 / Accepted: 8 October 2004 / Published: 8 December 2004

Abstract

In order to navigate its complex lifecycle, the malaria parasites must interact with a range of host cells. Examples of this are the invasion of hepatocytes by sporozoites and erythrocyte invasion by merozoites. This requirement for cell recognition brings with it the need to display cognate ligands on the parasite surface, and therefore the capacity of the host to develop defences against the infection. Even at a stage where the intracellular nature of erythrocyte development would appear to offer an opportunity for the parasite to be immunologically "silent", parasite-derived proteins are found on the surface of the infected erythrocyte. This review will discuss the proteins found on or associated with the surface of the infected erythrocyte and the resulting phenotypes.
Keywords: N/A N/A

Share and Cite

MDPI and ACS Style

Smith, J.D.; Craig, A.G. The Surface of the Plasmodium falciparum-infected Erythrocyte. Curr. Issues Mol. Biol. 2005, 7, 81-94. https://doi.org/10.21775/cimb.007.081

AMA Style

Smith JD, Craig AG. The Surface of the Plasmodium falciparum-infected Erythrocyte. Current Issues in Molecular Biology. 2005; 7(1):81-94. https://doi.org/10.21775/cimb.007.081

Chicago/Turabian Style

Smith, Joseph D., and Alister G. Craig. 2005. "The Surface of the Plasmodium falciparum-infected Erythrocyte" Current Issues in Molecular Biology 7, no. 1: 81-94. https://doi.org/10.21775/cimb.007.081

Article Metrics

Back to TopTop