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Review

Micro-RNA Modulation of Insect Virus Replication

by
Verna Monsanto-Hearne
and
Karyn N. Johnson
*
School of Biological Sciences, University of Queensland, Brisbane, Australia
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2019, 34(1), 61-82; https://doi.org/10.21775/cimb.034.061
Submission received: 2 March 2019 / Revised: 2 April 2019 / Accepted: 8 May 2019 / Published: 6 June 2019

Abstract

The outcome of virus infection in insects is impacted by regulation of both host and virus gene expression. A class of small RNAs called micro-RNAs (miRNA) have emerged as important regulators of gene expression that can influence the outcome of virus infection. miRNA regulation occurs at a comparatively late stage of gene expression, allowing for rapid control and fine-tuning of gene expression levels. Here we discuss the biogenesis of miRNAs from both host and virus genomes, the interactions that lead to regulation of gene expression, and the miRNA-mRNA interactions that lead to either antivirus or provirus consequences in the course of virus infection in insects.

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MDPI and ACS Style

Monsanto-Hearne, V.; Johnson, K.N. Micro-RNA Modulation of Insect Virus Replication. Curr. Issues Mol. Biol. 2019, 34, 61-82. https://doi.org/10.21775/cimb.034.061

AMA Style

Monsanto-Hearne V, Johnson KN. Micro-RNA Modulation of Insect Virus Replication. Current Issues in Molecular Biology. 2019; 34(1):61-82. https://doi.org/10.21775/cimb.034.061

Chicago/Turabian Style

Monsanto-Hearne, Verna, and Karyn N. Johnson. 2019. "Micro-RNA Modulation of Insect Virus Replication" Current Issues in Molecular Biology 34, no. 1: 61-82. https://doi.org/10.21775/cimb.034.061

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