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Volume 32
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10.21775/cimb.032.327
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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
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Review

Application of Omics and Bioinformatics Tools in Streptococcus Research

by
Min Liao
1,2,†,
Ting Tong
1,2,†,
Yawen Zong
1,2,†,
Xuedong Zhou
1,
Lei Cheng
1,2,
Ruijie Huang
1,3,*,
Biao Ren
1,* and
Gil Alterovitz
4
1
State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
2
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China
3
Department of Pediatric Dentistry, West China School of Stomatology, Sichuan University, Chengdu, China
4
Harvard Medical School, Boston Children’s Hospital, Boston, MA, USA
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Curr. Issues Mol. Biol. 2019, 32(1), 327-376; https://doi.org/10.21775/cimb.032.327
Submission received: 7 March 2019 / Revised: 11 April 2019 / Accepted: 12 May 2019 / Published: 5 June 2019
Versions Notes

Abstract

Researchers used to focus on analyzing single gene or protein expression of the microbes. But recently, genome, transcriptome, proteome and metabolome have gained more and more attention. Based on technologies of omics, including genomics, transcriptomics and metabolomics, a large quantity of information about cells, microbes and human, such as the information about phylogeny, virulence, antibiotic resistance and other aspects, has been revealed. Genus Streptococcus is one of the most invasive groups of bacteria that cause both human and animal diseases, threatening public health. In this review, we summarize the application of omics to analyze this genus-Streptococcus.
Keywords: application; omics; bioinformatics; tools; Streptococcus; research application; omics; bioinformatics; tools; Streptococcus; research

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MDPI and ACS Style

Liao, M.; Tong, T.; Zong, Y.; Zhou, X.; Cheng, L.; Huang, R.; Ren, B.; Alterovitz, G. Application of Omics and Bioinformatics Tools in Streptococcus Research. Curr. Issues Mol. Biol. 2019, 32, 327-376. https://doi.org/10.21775/cimb.032.327

AMA Style

Liao M, Tong T, Zong Y, Zhou X, Cheng L, Huang R, Ren B, Alterovitz G. Application of Omics and Bioinformatics Tools in Streptococcus Research. Current Issues in Molecular Biology. 2019; 32(1):327-376. https://doi.org/10.21775/cimb.032.327

Chicago/Turabian Style

Liao, Min, Ting Tong, Yawen Zong, Xuedong Zhou, Lei Cheng, Ruijie Huang, Biao Ren, and Gil Alterovitz. 2019. "Application of Omics and Bioinformatics Tools in Streptococcus Research" Current Issues in Molecular Biology 32, no. 1: 327-376. https://doi.org/10.21775/cimb.032.327

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