Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Heme Protein | kon(NO2−) (M−1 s−1) | kon(CO) (M−1 s−1) | Heme–Fe(II) Coordination |
---|---|---|---|
Mt-Nb(II) | 7.6 a | 5.5 × 104 b | 5C c |
At-Nb(II) | 9.3 a | 2.3 × 105 b | n.a. |
Dr-Nb(II) | 1.4 × 101 a | n.a. | 5C c |
Hs-Nb(II) | 5.8 a | 1.0 × 105 b | 5C c |
S-Hb(II) | 6.8 × 101 d | 3.0 × 105 e | 6C f |
At-Hb(II) class 1 | 2.0 × 101 g | 4.6 × 105 h | 6C (60%) + 5C (40%) i |
At-Hb(II) class 2 | 4.9 g | 1.0 × 106 h | 6C i |
Rice nonsymbiotic Hb(II) class 1 | 8.3 × 101 d | 2.4 × 106 e | 6C (65%) + 5C (35%) j |
Ma-Pgb(II) | 9.6 k 1.2 k | 2.1 × 107 l 1.1 × 106 l | 5C m |
Cc-Mb(II) type 1 | 5.3 n | n.a. | n.a. |
Cc-Mb(II) type 2 | 1.8 n | n.a. | n.a. |
Efc-Mb(II) | 2.9 o | 5.5 × 105 p | 5C q |
Pc-Mb(II) | 6.0 r | 5.0 × 105 h | 5C s |
Mm-Ngb(II) | 5.1 t | 2.6 × 102 u | 6C v |
Hs-Ngb(II) CysCD4-CysD5 | 1.2 × 10−1 w | 4.6 × 104 e | 6C x |
Hs-Ngb(II) CysCD4/CysD5 | 6.2 × 10−2 y | 4.0 × 103 e | 6C x |
Hs-Cygb(II) CysB2-CysE9 (monomer) | 3.2 × 101 z | 6.5 × 103 e | 6C x |
Hs-Cygb(II) CysB2/CysE9 (monomer) | 6.3 × 10−1 aa | 1.2 × 103 e | 6C x |
Hs-Cygb(II) CysB2/CysE9 (dimer) | 2.6 × 10−1 bb | n.a. | 6C cc |
Hs-Hb(II) T-state | 1.2 × 10−1 r | 7.8 × 104 dd | 5C ee |
Hs-Hb(II) R-state | 6.0 r | 1.1 × 107 ff | n.a. |
Hs-Hp1-1:Hb(II) | 7.3 gg | 1.4 × 106 hh | n.a. |
Hs-Hp2-2:Hb(II) | 1.2 × 101 gg | 5.2 × 106 hh | n.a. |
Mt-trHbN(II) | 1.6 × 101 ii | 3.8 × 106 jj | 5C kk |
Mt-trHbO(II) | 3.8 × 10−1 ii | 1.8 × 105 ll 1.4 × 104 ll | 5C mm |
Cj-trHbP(II) q | 4.3 ii | 4.5 × 107 nn 1.9 × 106 nn | 5C oo |
Hs-heme(II)-albumin | 1.3 pp | 4.0 × 106 qq | 5C rr |
Efc-Cytc(II) | 7.3 × 10−2 ss | n.a. | 6C tt |
Efc-Cytc(II) with CL | 2.6 ss | 1.0 × 107 uu | 5C vv |
Carboxymethylated Efc-Cytc(II) | 1.6 ww | 1.6 × 106 xx | 5C yy |
Carboxymethylated Efc-Cytc(II) with CL | 1.6 ww | n.a. | n.a. |
Efc-MP-11(II) | 3.4 zz | 9.7 × 106 aaa | 5C bbb |
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De Simone, G.; di Masi, A.; Tundo, G.R.; Coletta, M.; Ascenzi, P. Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study. Int. J. Mol. Sci. 2023, 24, 6553. https://doi.org/10.3390/ijms24076553
De Simone G, di Masi A, Tundo GR, Coletta M, Ascenzi P. Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study. International Journal of Molecular Sciences. 2023; 24(7):6553. https://doi.org/10.3390/ijms24076553
Chicago/Turabian StyleDe Simone, Giovanna, Alessandra di Masi, Grazia R. Tundo, Massimo Coletta, and Paolo Ascenzi. 2023. "Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study" International Journal of Molecular Sciences 24, no. 7: 6553. https://doi.org/10.3390/ijms24076553