SUMOylation and Major Depressive Disorder
Abstract
:1. Introduction
2. SUMOylation
3. SUMOylation in the Synapse
3.1. AMPARs
3.2. nNOS/NO Signaling
3.3. Ras/Raf/MEK/ERK Pathway
3.4. BDNF
3.5. SNARE Complex
3.6. Ion Channels
3.7. Receptors
3.7.1. Serotonin Receptors
3.7.2. Dopamine Transporters
3.7.3. G-Protein Coupled Receptors (GPCRs)
3.7.4. Kainite Receptors (KARs)
3.8. Cytoplasmic Polyadenylation Element-Binding Protein 3 (CPEB3)
4. Mitochondrial Dysfunction
4.1. Dynamin-Related Protein 1 (Drp1)
4.2. DJ-1
4.3. Peroxisomal Proliferator-Activated Receptor-γ Coactivator 1 α (PGC-1α)
4.4. Parkin
4.5. Parkin-Interacting Substrate (PARIS)
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Jeoung, S.-W.; Park, H.-S.; Ryoo, Z.Y.; Cho, D.-H.; Lee, H.-S.; Ryu, H.-Y. SUMOylation and Major Depressive Disorder. Int. J. Mol. Sci. 2022, 23, 8023. https://doi.org/10.3390/ijms23148023
Jeoung S-W, Park H-S, Ryoo ZY, Cho D-H, Lee H-S, Ryu H-Y. SUMOylation and Major Depressive Disorder. International Journal of Molecular Sciences. 2022; 23(14):8023. https://doi.org/10.3390/ijms23148023
Chicago/Turabian StyleJeoung, Seok-Won, Hyun-Sun Park, Zae Young Ryoo, Dong-Hyung Cho, Hyun-Shik Lee, and Hong-Yeoul Ryu. 2022. "SUMOylation and Major Depressive Disorder" International Journal of Molecular Sciences 23, no. 14: 8023. https://doi.org/10.3390/ijms23148023