Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: 12 November 2024 | Viewed by 110

Special Issue Editor


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Guest Editor
Department of Neuroscience, Brain Sciences Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Interests: human leukocyte antigen; vaccines against pathogens; vaccines against SARS-CoV-2; vaccines against cancer; human herpes and other viruses; cancer neoantigens
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Vaccines are used to prevent illnesses caused by pathogens. Vaccines contain antigens of pathogens that induce the host to produce antibodies against them. The success of vaccines in prevention or therapy depends on the ability of the host to make antibodies against the vaccine antigen(s). In turn, this depends on host immunogenetics, i.e., the availability of human leukocyte antigen (HLA) alleles that can form a complex with the antigen (or its fragments) to engage CD4+ T lymphocytes and then B cells for antibody formation. Thus, this antigen–HLA interaction is critical for the production of antibodies and success of the vaccine. This Special Issue centers on this association between vaccine antigens and HLA molecules that initiate antibody production. This journal welcomes original research articles and reviews on research areas focusing on antigen–HLA interactions in vaccine development and vaccine effectiveness. Research or review articles on the role of HLA in antigen presentation, antibody production, and vaccine effectiveness are welcome.

Prof. Dr. Apostolos P. Georgopoulos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccine
  • antigen
  • antibody
  • adjuvant
  • HLA
  • binding affinity
  • lymphocytes
  • antigen presenting cells

Published Papers

This special issue is now open for submission.
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