Advances in HIV Vaccine Development
Deadline for manuscript submissions: 31 July 2024 | Viewed by 135
Upon infection, HIV integrates into the host human genome and cannot be cleared with current treatments. Hence, sterile prevention—a high bar for vaccine development—remains of the utmost importance to halt virus spread and disease. HIV infection is also chronic, leading to the accumulation of enormous viral genetic diversity and multifaceted immune evasion, such as trimer packaging, glycan shield, conformational dynamics, and the immunodorminance of non-neutralizing epitopes, to name a few on the HIV envelope glycoprotein. These properties render HIV one of the most difficult viruses for vaccine development. Although neutralizing epitopes have been mapped to almost the entire surface of the HIV envelope, broadly neutralizing antibodies present numerous challenging traits and have not been induced with current vaccines.
In this Special Issue, all studies and reviews that shed new light on both prophylactic and therapeutic HIV vaccines are welcome.
Dr. Xueling Wu
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- envelope glycoprotein
- cellular immune response